Channel: Yale University

This collection includes bioRxiv and medRxiv papers from authors at Yale University.

4498 Articles

Genome-wide association study of Idiopathic Pulmonary Fibrosis susceptibility using clinically-curated European-ancestry datasets

Chin, D., Hernandez-Beeftink, T., Donoghue, L., Guillen-Guio, B., Leavy, O. C., Adegunsoye, A., Booth, H. L., Fahy, W. A., Fingerlin, T. E., Gooptu, B., Hall, I. P., Hart, S. P., Hill, M. R., Hirani, N., Hubbard, R. B., Johnson, S., Kaminski, N., Lorenzo-Salazar, J. M., Ma, S.-F., McAnulty, R. J., McCarthy, M., Stockwell, A. D., Maher, T. M., Millar, A. B., Molyneaux, P. L., Molina-Molina, M., Navaratnam, V., Neighbors, M., Oldham, J. M., Parfrey, H., Saini, G., Sayers, I., Sheng, X. R., Stewart, I. D., Strek, M. E., Tobin, M. D., Whyte, M. K., Zarcone, M. C., Zhang, Y., Martinez, F., Yaspan

10.1101/2025.01.30.25321017 — Posted: 2025-02-02

Simultaneous profiling of native-state proteomes and transcriptomes of neural cell types using proximity labeling

Ramelow, C. C., Dammer, E. B., Xiao, H., Cheng, L., Kumar, P., Espinosa-Garcia, C., Sampson, M. M., Nelson, R. S., Malepati, S., Kour, D., Kumari, R., Guo, Q., Bagchi, P., Duong, D. M., Seyfried, N. T., Sloan, S. A., Rangaraju, S.

10.1101/2025.01.29.635500 — Posted: 2025-02-01

Improving American chestnut resistance to two invasive pathogens through genome-enabled breeding

Westbrook, J. W., Malukiewicz, J., Sreedasyam, A., Jenkins, J. W., Zhang, Q., Lakoba, V., Fitzsimmons, S. F., Van Clief, J., Collins, K., Hoy, S., Stark, C., Grabowski, L., Jenkins, E., Saielli, T., Jarrett, B. T., Wigfield, L., Kerwien, L. M., Wilbur, C., Sandercock, A., Craddock, J. H., Zannini, P., Kerio, S., Zhebentyayeva, T., Fan, S., Thomas, A., Abbott, A., Nelson, C. D., Xia, X., Williams, M., Boston, L., Plott, C., Carle, F., Swatt, J., Ostroff, J., Jeffers, S., Mckeever, K., Smith, E., Ellis, T. J., James, J. B., Sisco, P., Newhouse, A. E., Carlson, E., Powell, W. A., Hebard, F. V., S

10.1101/2025.01.30.635736 — Posted: 2025-02-01

Geometric influences on the regional organization of the mammalian brain

Pang, J. C., Robinson, P. A., Aquino, K. M., Levi, P. T., Holmes, A., Markicevic, M., Shen, X., Funck, T., Palomero-Gallagher, N., Kong, R., Yeo, B. T. T., Tiego, J., Bellgrove, M. A., Constable, R. T., Lake, E. M., Breakspear, M., Fornito, A.

10.1101/2025.01.30.635820 — Posted: 2025-02-01

High resolution structures of Myosin-IC reveal a unique actin-binding orientation, ADP release pathway, and power stroke trajectory

Chavali, S. S., Carman, P. J., Shuman, H., Ostap, E. M., Sindelar, C. V.

10.1101/2025.01.10.632429 — Posted: 2025-01-30

The first complete 3D reconstruction and morphofunctional mapping of an insect eye

Makarova, A. A., Chua, N. J., Diakova, A. V., Desyatirkina, I. A., Gunn, P., Pang, S., Xu, C. S., Hess, H. F., Chklovskii, D. B., Polilov, A. A.

10.1101/2024.09.30.615804 — Posted: 2025-01-29

Post-Ictal Sleep Changes in Human Focal Epilepsy

Kremen, V., Cao, Y., Gerla, V., Mivalt, F., Sladky, V., St Louis, E. K., Bower, M. R., Brinkmann, B. H., Miller, K. J., Van Gompel, J., Denison, T., Leyde, K., Worrell, G. A.

10.1101/2025.01.28.25321285 — Posted: 2025-01-29

APOE-ϵ4-induced Fibronectin at the blood-brain barrier is a conserved pathological mediator of disrupted astrocyte-endothelia interaction in Alzheimer's disease

Bhattarai, P., Yilmaz, E., Cakir, E. O., Yuceer Korkmaz, H., Lee, A. J., Ma, Y., Celikkaya, H., Cosacak, M. I., Haage, V., Wang, X., Nelson, N., Lin, W., Zhang, Y., Nuriel, T., Juelich, D., Is, O., Scott, H., de Jager, P., Fisher, E., Tubessing, K., Teich, A. F., Bertucci, T., Temple, S., Ertekin-Taner, N., Vardarajan, B. N., Mayeux, R., Kizil, C.

10.1101/2025.01.24.634732 — Posted: 2025-01-27

Epigenetic priming promotes acquisition of tyrosine kinase inhibitor resistance and oncogene amplification in human lung cancer

Starble, R., Sun, E. G., Gbyli, R., Radda, J., Lu, J., Jensen, T. B., Sun, N., Khudaverdyan, N., Hu, B., Melnick, M. A., Zhao, S., Roper, N., Wang, G. G., Song, J., Politi, K., Wang, S., Xiao, A.

10.1101/2025.01.26.634826 — Posted: 2025-01-27

Integrating bulk and single cell RNA-seq refines transcriptomic profiles of individual C. elegans neurons

Barrett, A., Varol, E., Weinreb, A., Taylor, S. R., McWhirter, R. M., Cros, C. C., Vidal, B., Basaravaju, M., Poff, A., Tipps, J. A., Majeed, M., Wang, C., Bayer, E. A., Reilly, M. B., Yemini, E., Sun, H., Hobert, O., Miller, D. M., Hammarlund, M.

10.1101/2025.01.26.634951 — Posted: 2025-01-27

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