Channel: Yale University

This collection includes bioRxiv and medRxiv papers from authors at Yale University.

4310 Articles

Leveraging Functional Annotations in Genetic Risk Prediction for Human Complex Diseases

Yiming Hu, Qiongshi Lu, Ryan Powles, Xinwei Yao, Can Yang, Fang Fang, Xinran Xu, Hongyu Zhao

10.1101/058768 — Posted: 2016-06-13

KIF1A/UNC-104 transports ATG-9 to regulate neurodevelopment and autophagy at synapses

Andrea K.H. Stavoe, Sarah E. Hill, Daniel A. Colón-Ramos

10.1101/057166 — Posted: 2016-06-05

Large-scale trans-eQTLs affect hundreds of transcripts and mediate patterns of transcriptional co-regulation

Boel Brynedal, JinMyung Choi, Towfique Raj, Robert Bjornson, Barbara Stranger, Benjamin Neale, Benjamin Voight, Chris Cotsapas

10.1101/056283 — Posted: 2016-05-31

Goggatomy: a Method for Opening Small Cuticular Compartments in Arthropods for Physiological Experiments

Alan R Kay, Davide Raccuglia, Jon Scholte, Elena Loukianova, Christopher A Barwacz, Steven A Armstrong, C Allan Guymon, Michael N Nitabach, Daniel F Eberl

10.1101/053298 — Posted: 2016-05-18

Localized structural frustration for evaluating the impact of sequence variants

Sushant Kumar, Declan Clarke, Mark Gerstein

10.1101/052027 — Posted: 2016-05-08

AC-PCA: simultaneous dimension reduction and adjustment for confounding variation

Zhixiang Lin, Can Yang, Ying Zhu, John C. Duchi, Yao Fu, Yong Wang, Bai Jiang, Mahdi Zamanighomi, Xuming Xu, Mingfeng Li, Nenad Sestan, Hongyu Zhao, Wing Hung Wong

10.1101/040485 — Posted: 2016-04-19

Chm7 and Heh1 form a nuclear envelope subdomain for nuclear pore complex quality control

Brant M Webster, David J Thaller, Jens Jaeger, Sarah E Ochmann, C. Patrick Lusk

10.1101/049148 — Posted: 2016-04-18

Assessment of pharmacogenomic agreement

Zhaleh Safikhani, Nehme El-Hachem, Rene Quevedo, Petr Smirnov, Anna Goldenberg, Nicolai Juul Birkbak, Christopher E Mason, Christos Hatzis, Leming Shi, Hugo JWL Aerts, John Quackenbush, Benjamin Haibe-Kains

10.1101/048470 — Posted: 2016-04-13

The mutational landscape of EGFR-, MYC-, and Kras- driven genetically-engineered mouse models of lung adenocarcinoma

David McFadden, Katerina Politi, Arjun Bhutkar, Frances K Chen, Xiaoling Song, Mono Pirun, Philip M Santiago, Caroline Kim, James T Platt, Emily Lee, Emily Hodges, Adam P Rosebrock, Roderick Bronson, Nicholas D Socci, Gregory Hannon, Tyler Jacks, Harold Varmus

10.1101/048058 — Posted: 2016-04-11

The contribution of alternative splicing probability to the coding expansion of the genome

Fernando Carrillo Oesterreich, Hugo Bowne-Anderson, Jonathon Howard

10.1101/048124 — Posted: 2016-04-11

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