Channel: Yale University

This collection includes bioRxiv and medRxiv papers from authors at Yale University.

4061 Articles

Ultra-rare genetic variation in the epilepsies: a whole-exome sequencing study of 17,606 individuals

Epi25 Collaborative, , Feng, Y.-C. A., Howrigan, D. P., Abbott, L. E., Tashman, K., Cerrato, F., Singh, T., Heyne, H., Byrnes, A., Churchhouse, C., Lal, D., Heinzen, E. L., Cavalleri, G. L., Hakonarson, H., Helbig, I., Krause, R., May, P., Weckhuysen, S., Petrovski, S., Kamalakaran, S., Sisodiya, S. M., Cossette, P., Cotsapas, C., De Jonghe, P., Dixon-Salazar, T., Guerrini, R., Kwan, P., Marson, A. G., Stewart, R., Depondt, C., Dlugos, D. J., Scheffer, I. E., Striano, P., Freyer, C., McKenna, K., Regan, B. M., Bellows, S. T., Leu, C., Bennett, C. A., Johns, E. M. C., Macdonald, A., Shilling

10.1101/525683 — Posted: 2019-01-21

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

Lam, M., Hill, W. D., Trampush, J. W., Yu, J., Knowles, E., Davies, G., Stahl, E., Huckins, L., Liewald, D. C., Djurovic, S., Melle, I., Sundet, K., Christoforou, A., Reinvang, I., DeRosse, P., Lundervold, A., Steen, V. M., Espeseth, T., Raikkonen, K., Widen, E., Palotie, A., Eriksson, J. G., Giegling, I., Konte, B., Hartmann, A. M., Roussos, P., Giakoumaki, S., Burdick, K. E., Payton, A., Ollier, W., Chiba-Falek, O., Attix, D. K., Need, A. C., Cirulli, E. T., Voineskos, A. N., Stefanis, N., Avramopoulos, D., Hatzimanolis, A., Arking, D. E., Smyrnis, N., Bilder, R. M., Freimer, N. A., Cannon

10.1101/519967 — Posted: 2019-01-20

Genomewide Analyses of Psychological Resilience in US Army Soldiers

Stein, M., Choi, K. W., Jain, S., Campbell-Sills, L., Chen, C.-Y., Gelernter, J., He, F., Heeringa, S. G., Maihofer, A. X., Nievergelt, C. M., Nock, M. K., Ripke, S., Sun, X., Kessler, R. C., Smoller, J. W., Ursano, R. J.

10.1101/516716 — Posted: 2019-01-20

O-GlcNAc transferase suppresses necroptosis and liver fibrosis

Zhang, B., Li, M.-D., Yin, R., Liu, Y., Yang, Y., Mitchell-Richards, K. A., Nam, J. H., Li, R., Wang, L., Iwakiri, Y., Chung, D., Robert, M. E., Ehrlich, B. E., Bennett, A. M., Yu, J., Nathanson, M., Yang, X.

10.1101/519975 — Posted: 2019-01-14

Simulation of the mechanics of actin assembly during endocytosis in yeast

Nickaeen, M., Berro, J., Pollard, T. D., Slepchenko, B. M.

10.1101/518423 — Posted: 2019-01-11

A statistical framework for cross-tissue transcriptome-wide association analysis

Hu, Y., Li, M., Lu, Q., Weng, H., Wang, J., Zekavat, S. M., Yu, Z., Li, B., Gu, J., Muchnik, S., Shi, Y., Kunkle, B. W., Mukherjee, S., Natarajan, P., Naj, A., Kuzma, A., Zhao, Y., Crane, P. K., Alzheimer's Disease Genetics Consortium, , Lu, H., Zhao, H.

10.1101/286013 — Posted: 2019-01-10

Human Phageprints: A high-resolution exploration of oral phages reveals globally-distributed phage families with individual-specific and temporally-stable community compositions

Mahmoudabadi, G., Homyk, K., Catching, A., Foley, H., Tadmor, A., Mahmoudabadi, A., Cheung, A., Phillips, R.

10.1101/516864 — Posted: 2019-01-10

WNT/β-CATENIN modulates the axial identity of ES derived human neural crest

Gomez, G. A., Prasad, M. S., Wong, M., Charney, R. M., Shelar, P., Sandhu, N., Hackland, J., Hernandez, J. C., Leung, A. W., Garcia-Castro, M. I.

10.1101/514570 — Posted: 2019-01-08

Comprehensive substrate specificity profiling of the human nek kinome reveals unexpected signaling outputs

van de Kooij, B., Creixell, P., van Vlimmeren, A., Joughin, B., Miller, C. J., Haider, N., Linding, R., Stambolic, V., Turk, B. E., Yaffe, M. B.

10.1101/515221 — Posted: 2019-01-08

Exploring Single-Cell Data with Deep Multitasking Neural Networks

Amodio, M., van Dijk, D., Srinivasan, K., Chen, W. S., Mohsen, H., Moon, K. R., Campbell, A., Zhao, Y., Wang, X., Venkataswamy, M., Desai, A., V., R., Kumar, P., Montgomery, R., Wolf, G., Krishnaswamy, S.

10.1101/237065 — Posted: 2019-01-03

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