Channel: Yale University

This collection includes bioRxiv and medRxiv papers from authors at Yale University.

4057 Articles

Integrating HiTOP and RDoC Frameworks Part I: Genetic Architecture of Externalizing and Internalizing Psychopathology

Davis, C. N., Khan, Y., Toikumo, S., Jinwala, Z., Boomsma, D. I., Levey, D. F., Gelernter, J., Kember, R. L., Kranzler, H. R.

10.1101/2024.04.06.24305166 — Posted: 2025-02-05

ASTRO: Automated Spatial Whole-Transcriptome RNA-Expression Workflow

Zhang, D., Chu, Z., Huo, Y., Bai, Z., Fan, R., Lu, J., Gerstein, M.

10.1101/2025.01.24.634814 — Posted: 2025-02-05

Genome-wide association studies of binge-eating behaviour and anorexia nervosa yield insights into the unique and shared biology of eating disorder phenotypes

Termorshuizen, J. D., Davies, H. L., Lee, S. H., Huckins, L. M., Bulik, C. M., Breen, G., Coleman, J. R., Eating Disorder Working Group of the Psychiatric Genomics Consortium

10.1101/2025.01.31.25321397 — Posted: 2025-02-04

Targeted ubiquitination of NaV1.8 reduces sensory neuronal excitability

Tyagi, S., Ghovanloo, M.-R., Alsaloum, M., Effraim, P., Higerd-Rusli, G. P., Dib-Hajj, F., Zhao, P., Liu, S., Waxman, S. G., Dib-Hajj, S. D.

10.1101/2025.02.04.636451 — Posted: 2025-02-04

Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits.

Johnson, E. C., Lai, D., Miller, A. P., Hatoum, A. S., Deak, J. D., Balbona, J. V., Baranger, D. A., Galimberti, M., Sanichwankul, K., Thorgeirsson, T., Colbert, S. M., Sanchez-Roige, S., Adhikari, K., Docherty, A., Degenhardt, L., Edwards, T., Fox, L., Giannelis, A., Jeffries, P., Korhonen, T., Morrison, C., Nunez, Y. Z., Palviainen, T., Su, M.-H., Romero Villela, P. N., Wetherill, L., Willoughby, E. A., Zellers, S., Bierut, L., Buchwald, J., Copeland, W., Corley, R., Friedman, N. P., Foroud, T. M., Gillespie, N. A., Gizer, I. R., Heath, A. C., Hickie, I. B., Kaprio, J. A., Keller, M. C., Lee

10.1101/2025.01.29.25320962 — Posted: 2025-02-03

Comparative transcriptional analysis reveals gene expression changes in spore germination of opportunistic pathogenic fungi

Kim, D.-W., Ebert, M. K., Moonjely, S., Wang, Z., Yarden, O., Townsend, J. P., Trail, F.

10.1101/2025.02.03.636182 — Posted: 2025-02-03

Proliferative arrest induces neuron differentiation and innate immune responses in control and Creutzfeldt-Jakob Disease agent (CJ) infected rat septal neurons

pagano, n., aguilar, g., Garcia-Milian, R., manuelidis, l.

10.1101/2024.07.26.605349 — Posted: 2025-02-03

Genome-wide association study of Idiopathic Pulmonary Fibrosis susceptibility using clinically-curated European-ancestry datasets

Chin, D., Hernandez-Beeftink, T., Donoghue, L., Guillen-Guio, B., Leavy, O. C., Adegunsoye, A., Booth, H. L., Fahy, W. A., Fingerlin, T. E., Gooptu, B., Hall, I. P., Hart, S. P., Hill, M. R., Hirani, N., Hubbard, R. B., Johnson, S., Kaminski, N., Lorenzo-Salazar, J. M., Ma, S.-F., McAnulty, R. J., McCarthy, M., Stockwell, A. D., Maher, T. M., Millar, A. B., Molyneaux, P. L., Molina-Molina, M., Navaratnam, V., Neighbors, M., Oldham, J. M., Parfrey, H., Saini, G., Sayers, I., Sheng, X. R., Stewart, I. D., Strek, M. E., Tobin, M. D., Whyte, M. K., Zarcone, M. C., Zhang, Y., Martinez, F., Yaspan

10.1101/2025.01.30.25321017 — Posted: 2025-02-02

Simultaneous profiling of native-state proteomes and transcriptomes of neural cell types using proximity labeling

Ramelow, C. C., Dammer, E. B., Xiao, H., Cheng, L., Kumar, P., Espinosa-Garcia, C., Sampson, M. M., Nelson, R. S., Malepati, S., Kour, D., Kumari, R., Guo, Q., Bagchi, P., Duong, D. M., Seyfried, N. T., Sloan, S. A., Rangaraju, S.

10.1101/2025.01.29.635500 — Posted: 2025-02-01

Improving American chestnut resistance to two invasive pathogens through genome-enabled breeding

Westbrook, J. W., Malukiewicz, J., Sreedasyam, A., Jenkins, J. W., Zhang, Q., Lakoba, V., Fitzsimmons, S. F., Van Clief, J., Collins, K., Hoy, S., Stark, C., Grabowski, L., Jenkins, E., Saielli, T., Jarrett, B. T., Wigfield, L., Kerwien, L. M., Wilbur, C., Sandercock, A., Craddock, J. H., Zannini, P., Kerio, S., Zhebentyayeva, T., Fan, S., Thomas, A., Abbott, A., Nelson, C. D., Xia, X., Williams, M., Boston, L., Plott, C., Carle, F., Swatt, J., Ostroff, J., Jeffers, S., Mckeever, K., Smith, E., Ellis, T. J., James, J. B., Sisco, P., Newhouse, A. E., Carlson, E., Powell, W. A., Hebard, F. V., S

10.1101/2025.01.30.635736 — Posted: 2025-02-01

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