Channel: Yale University

This collection includes bioRxiv and medRxiv papers from authors at Yale University.

5334 Articles

miR-34/449 miRNAs regulate choroid plexus ciliogenesis to control cerebrospinal fluid production

Mao, S., Song, R., Jovanovic, A., Jin, S., Pang, S., Jorgens, D. M., Wendland, M. F., Zimmerman, A., Lin, D., Xuan, Z., Xu, C. S., Hess, H. F., Upadhyayula, S., He, L.

10.64898/2026.08.30.747939 — Posted: 2026-09-01

Structural characterization the LlaI anti-phage defense system reveals insights into the evolution of nucleotide specificity and the organization of DNA binding in McrBC restriction complexes

Bui, A. Q., Hosford, C. J., Niu, Y., Santiago, E., Moraga, D., Wagner, M. M., Chappie, J. S.

10.64898/2026.08.31.748284 — Posted: 2026-09-01

Obesity Endotypes Unmask Heterogeneous Responses to Healthy Lifestyle Behaviors

Malik, D., Kim, M. S., Shim, I., Sui, Y., Abou-Karam, R., Song, M., Won, H.-H., Natarajan, P., Ellinor, P. T., Fahed, A. C.

10.64898/2026.08.25.26361367 — Posted: 2026-08-31

A germline KDM3C polymorphism impairs DNA repair and sensitizes to chemoradiotherapy

Hasan, A., Demidova, E. V., Priyadarshini, P., Czyzewicz, P., Gathuka, L., Murayama, T., Zhou, Y., Kiss, Z. A., Shastry, R. K., Andrake, M., Hearne, G., Devarajan, K., Wu, C., Shah, A., Schultz, B. M., Connolly, D. C., Rosen, G. L., Canadas, I., Liu, J. C., Burtness, B. A., Smith, J. J., Dunbrack, R. L., Golemis, E. A., Whetstine, J. R., Meyer, J. E., Arora, S.

10.64898/2026.08.26.26360896 — Posted: 2026-08-31

Genomic Architecture of Migraine: A Multi ancestry GWAS Meta analysis of 2.5 Million Participants

Overstreet, C., Galimberti, M., Harsan, K. T., Beck, S. E., Hirsch, J., Sariya, S., Ferolito, B. R., Zhou, Y., Zhang, Y., Weinheimer, E. I., Lacobelle, A., Nunez, Y., The VA Million Veteran Program, , Kranzler, H. R., Gaziano, J. M., Stein, M., Gottschalk, C., Choi, K. W., Pereira, A. W., Deak, J. D., Pathak, G. A., Levey, D. F., Gelernter, J.

10.64898/2026.08.28.26361638 — Posted: 2026-08-31

Identification of genetic variants in Pfs25 and functional evaluation in mosquito infection

Orfano, A., Cisse, A., Guo, Y., Han, L., Fikadu, N., Thiam, L. G., Ba, A., Li, R., Pouye, M. N., Mangou, K., Moore, A. J., Sene, S. D., Diallo, F., Ngom, E. M., Sadio, B., Mbengue, A., Membi, C., Ngasala, B., Bazie, T., Some, F. A., Olson, N., Patel, S. D., Shapiro, L., Parikh, S., Foy, B. D., Cappello, M., Vigan-Womas, I., Premji, Z., Dabire, R. K., Ouedraogo, J.-B., Sheng, Z., Bei, A. K.

10.64898/2026.08.25.26361130 — Posted: 2026-08-31

The Psychological Footprint of Unruptured Intracranial Aneurysm Discovery

Renedo, D., Chen, H., Sheth, K. N., Gandhi, D., Malhotra, A., Matouk, C. C.

10.64898/2026.08.25.26361377 — Posted: 2026-08-31

Clinical Reference Percentiles for AI-derived Epicardial Adipose Tissue: A Multicenter Study

Kamagate, A., Shanbhag, A., Buchwald, M., Miller, R. J. H., Khanna, S., Zuhair Kassem, T., Kwiecinski, J., Bullock-Palmer, R., Zhang, W., Marcinkiewicz, A. M., Yi, J., Ramirez, G., Lemley, M., Killekar, A., Kavanagh, P. B., Liang, J. X., Slipczuk, L., Travin, M. I., Alexanderson, E., Carvajal-Juarez, I., Packard, R. R., Al-Mallah, M., Ruddy, T. D., deKemp, R. A., Buechel, R. R., Einstein, A. J., Acampa, W., Knight, S., Le, V. T., Mason, S., Rosamond, T. L., Miller, E. J., Chareonthaitawee, P., Berman, D. S., Dey, D., Di Carli, M. F., Slomka, P.

10.64898/2026.08.28.26360111 — Posted: 2026-08-31

Engineering Spatial Control of Bacterial Organelles

Hoang, Y., Jadhav, P. V., Trettel, D., Baumann, R. M., Dow, R. E., Kwon, S., Matej, K., Byrne, J. A., Azaldegui, C. A., Liu, Y., Giessen, T. W., Pi, H., Mosalaganti, S., Vecchiarelli, A. G.

10.1101/2025.09.22.677801 — Posted: 2026-08-29

ClC-7 links PIKfyve inhibition to Rab-dependent LRRK2 activity at lysosomes

Clegg, D., Bentley-DeSousa, A., Roczniak-Ferguson, A., Ferguson, S. M.

10.1101/2025.11.19.689251 — Posted: 2026-08-29

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