Channel: University of Massachusetts Chan Medical School

This collection includes bioRxiv and medRxiv papers from authors at University of Massachusetts Chan Medical School .

1006 Articles

A cohesin traffic pattern genetically linked to gene regulation

Valton, A.-L., Venev, S. V., Mair, B., Khokhar, E., Tong, A. H., Usaj, M., Chan, K. S., Pai, A., Moffat, J., Dekker, J.

10.1101/2021.07.29.454218 — Posted: 2021-07-30

Evolution of protection after maternal immunization for respiratory syncytial virus in cotton rats

Blanco, J. C. G., McGinnes-Cullen, L., Kamali, A., Sylla, F., Boukhavalova, M., Morrison, T.

10.1101/2021.07.30.454440 — Posted: 2021-07-30

The epithelial-specific ER stress sensor IRE1β enables host-microbiota crosstalk to affect colon goblet cell development

Grey, M. J., De Luca, H., Ward, D. V., Kreulen, I. A. M., Foley, S. E., Thiagarajah, J. R., McCormick, B. A., Turner, J. R., Lencer, W. I.

10.1101/2021.07.28.453864 — Posted: 2021-07-28

Loss of Nuclear DNA Ligase III Reverts PARP Inhibitor Resistance in BRCA1/53BP1 Double-deficient Cells by Exposing ssDNA Gaps

Paes Dias, M., Tripathi, V., Heijden, I. v. d., Cong, K., Manolika, E.-M., Bhin, J., Gogola, E., Galanos, P., Annunziato, S., Lieftink, C., Andujar-Sanchez, M., Chakrabarty, S., Smith, G. C. M., Ven, M. v. d., Beijersbergen, R. L., Bartkova, J., Rottenberg, S., Cantor, S., Bartek, J., Chaudhuri, A. R., Jonkers, J.

10.1101/2021.03.24.436323 — Posted: 2021-07-20

The ASC Speck And NLRP3 Inflammasome Function Are Spatially And Temporally Distinct

Harton, J., Nagar, A., Rahman, T.

10.1101/2021.07.19.452947 — Posted: 2021-07-19

Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance

Skovso, S., Panzhinskiy, E., Kolic, J., Cen, H. H., Dionne, D. A., Dai, X.-Q., Sharma, R. B., Elghazi, L., Ellis, C. E., Faulkner, K., Marcil, S. A. M., Overby, P., Noursadeghi, N., Hutchinson, D., Hu, X., Modi, H., Wildi, J., Botezelli, J. D., Noh, H. L., Suk, S., Gablaski, B., Bautista, A., Kim, R., Cras-Meneur, C., Flibotte, S., Sinha, S., Luciani, D. S., Nislow, C., Rideout, E. J., Cytrynbaum, E. N., Kim, J., Bernal-Mizrachi, E., Alonso, L. C., MacDonald, P. E., Johnson, J. D.

10.1101/2020.10.15.338160 — Posted: 2021-07-19

Complete genomic and epigenetic maps of human centromeres

Altemose, N., Logsdon, G. A., Bzikadze, A. V., Sidhwani, P., Langley, S. A., Caldas, G. V., Hoyt, S. J., Uralsky, L., Ryabov, F. D., Shew, C. J., Sauria, M. E. G., Borchers, M., Gershman, A., Mikheenko, A., Shepelev, V. A., Dvorkina, T., Kunyavskaya, O., Vollger, M. R., Rhie, A., McCartney, A. M., Asri, M., Lorig-Roach, R., Shafin, K., Aganezov, S., Olson, D., Gomes de Lima, L., Potapova, T., Hartley, G. A., Haukness, M., Kerpedjiev, P., Gusev, F., Tigyi, K., Brooks, S., Young, A., Nurk, S., Koren, S., Salama, S. R., Paten, B., Rogaev, E. I., Streets, A., Karpen, G. H., Dernburg, A. F., Sulliv

10.1101/2021.07.12.452052 — Posted: 2021-07-19

TAF4b transcription networks regulating early oocyte differentiation

Gura, M. A., Relovska, S., Abt, K. M., Seymour, K. A., Wu, T., Kaya, H., Turner, J., Fazzio, T. G., Freiman, R. N.

10.1101/2021.07.18.452838 — Posted: 2021-07-18

c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease

Smith, A. O., Jonassen, J. A., Preval, K. M., Davis, R. J., Pazour, G. J.

10.1101/2021.07.15.452451 — Posted: 2021-07-15

mtDNA replication in dysfunctional mitochondria promotes deleterious heteroplasmy via the UPRmt

Yang, Q., Liu, P., Anderson, N., Shpilka, T., Du, Y., Uma Naresh, N., Luk, K., Lavelle, J., Zeinert, R., Chien, P., Wolfe, S., Haynes, C.

10.1101/2020.09.01.274472 — Posted: 2021-07-14

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