Channel: Columbia University

This collection includes bioRxiv and medRxiv papers from authors at Columbia University.

4963 Articles

The Host Cell ViroCheckpoint: Identification and Pharmacologic Targeting of Novel Mechanistic Determinants of Coronavirus-Mediated Hijacked Cell States

Laise, P., Bosker, G., Sun, X., Shen, Y., Douglass, E. F., Karan, C., Realubit, R. B., Pampou, S., Califano, A., Alvarez, M. J.

10.1101/2020.05.12.091256 — Posted: 2020-05-17

Community-scale Synchronization and Temporal Partitioning of Gene Expression, Metabolism, and Lipid Biosynthesis in Oligotrophic Ocean Surface Waters

Muratore, D., Boysen, A. K., Harke, M. J., Becker, K. W., Casey, J. R., Coesel, S. N., Mende, D. R., Wilson, S. T., Aylward, F. O., Eppley, J. M., Vislova, A., Peng, S., Rodriguez-Gonzalez, R. A., Beckett, S. J., Armbrust, E. V., DeLong, E. F., Karl, D. M., White, A. E., Zehr, J. P., Van Mooy, B. A. S., Dyhrman, S. T., Ingalls, A. E., Weitz, J. S.

10.1101/2020.05.15.098020 — Posted: 2020-05-17

The low complexity motif of cytoplasmic polyadenylation element binding protein 3 (CPEB3) is critical for the trafficking of its targets in neurons

Ford, L., Asok, A., Tripp, A. D., Parro, C., Fitzpatrick, M., de Solis, C. A., Shafiian, N., Fioriti, L., Soni, R. K., Kandel, E.

10.1101/2020.05.16.100032 — Posted: 2020-05-17

Lipoic acid biosynthesis is essential for Plasmodium falciparum transmission and influences redox response and carbon metabolism of parasite asexual blood stages

Biddau, M., Kumar, S. T. R., Henrich, P., Laine, L. M., Blackburn, G. J., Chokkathukalam, A., Li, T. B., Sim, K. L., Hoffman, S. L., Barrett, M. P., Coombs, G. H., McFadden, G. I., Fidock, D. A., Muller, S., Sheiner, L.

10.1101/2020.05.17.099630 — Posted: 2020-05-17

Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis

O'Neill, J., Hoyle, N. P., Robertson, J. B., Edgar, R. S., Beale, A. D., Peak-Chew, S. Y., Day, J., Costa, A. S. H., Frezza, C., Causton, H. C.

10.1101/2020.05.14.095521 — Posted: 2020-05-16

The effect of boundaries on grid cell patterns

Monsalve-Mercado, M. M., Leibold, C.

10.1101/2020.05.16.099168 — Posted: 2020-05-16

COVID-19 infection results in alterations of the kynurenine pathway and fatty acid metabolism that correlate with IL-6 levels and renal status

Thomas, T., Stefanoni, D., Reisz, J. A., Nemkov, T., Bertolone, L., Francis, R. O., Hudson, K. E., Zimring, J. C., Hansen, K. C., Hod, E. A., Spitalnik, S. L., D'Alessandro, A.

10.1101/2020.05.14.20102491 — Posted: 2020-05-16

Establishing a transcriptome-based drug discovery paradigm for neurodevelopmental disorders

Dhindsa, R. S., Zoghbi, A. W., Krizay, D. K., Vasavda, C., Goldstein, D. B.

10.1101/2020.05.13.093468 — Posted: 2020-05-15

Distinct pathways of homologous recombination controlled by the SWS1-SWSAP1-SPIDR complex

prakash, r., sandoval, t., Morati, F., Zagelbaum, J. A., Taylor, B., Desclos, E. C., Wang, R., Sullivan, M. R., Rein, H. L., Bernstein, K. A., Krawczyk, P. M., Gautier, J., Modesti, M., Vanoli, F., Jasin, M.

10.1101/2020.05.15.098848 — Posted: 2020-05-15

De novo variants in SNAP25 cause an early-onset developmental and epileptic encephalopathy

Klöckner, C., Sticht, H., Zacher, P., Popp, B., Bakker, D. P., Barwick, K., Bonfert, M. V., Brilstra, E. H., Care4Rare Canada Consortium, , Chung, W. K., Clarke, A. J., Devine, P., Friedman, J., Gates, A., Horvath, G., Keller-Ramey, J., Keren, B., Kurian, M. A., Lee, V., Leppig, K. A., Lundgren, J., McDonald, M. T., McTague, A., Mefford, H. C., Mignot, C., Mikati, M. A., Nava, C., Raymond, F. L., Sampson, J. R., Sanchis-Juan, A., Shashi, V., Shieh, J. T. C., Shinawi, M., Slavotinek, A., Stödberg, T., Stong, N., Sullivan, J. A., Taylor, A. C., Toler, T. L., van den Bogaard, M.-J., van der Cr

10.1101/2020.05.11.20095141 — Posted: 2020-05-15

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