Channel: Columbia University

This collection includes bioRxiv and medRxiv papers from authors at Columbia University.

4787 Articles

Complement C3 vs C5 inhibition in severe COVID-19: early clinical findings reveal differential biological efficacy

Mastellos, D. C., Pires da Silva, B. G. P., Fonseca, B. A. L., Fonseca, N. P., Martins, M. A., Mastaglio, S., Ruggeri, A., Sironi, M., Radermacher, P., Skendros, P., Ritis, K., Manfra, I., Iacobelli, S., Huber-Lang, M., Nilsson, B., Yancopoulou, D., Connolly, E. S., Garlanda, C., Ciceri, F., Risitano, A. M., Calado, R. T., Lambris, J. D.

10.1101/2020.08.17.20174474 — Posted: 2020-08-21

Generalizability of Polygenic Risk Scores for Breast Cancer in the Multiethnic eMERGE Study

Liu, C., Zeinomar, N., Chung, W. K., Kiryluk, K., Ghravi, A. G., Hripcsak, G., Crew, K. D., Shang, N., Khan, A., Fasel, D., Manolio, T. A., Jarvik, G. P., Rowley, R., Justice, A. E., Rahm, A. K., Fullerton, S. M., Smoller, J. W., Larson, E. B., Crane, P. K., Dikilitas, O., Terry, M. B., Weng, C.

10.1101/2020.08.17.20176685 — Posted: 2020-08-21

Is more better? An analysis of toxicity and response outcomes from dose-finding clinical trials in cancer

Brock, K., Homer, V., Soul, G., Potter, C., Chiuzan, C., Lee, S.

10.1101/2020.08.18.20177212 — Posted: 2020-08-21

Brain Amyloid and the Transition to Dementia in Down Syndrome

Keator, D. B., Doran, E., Taylor, L. A., Phelan, M. J., Hom, C., Tseung, K., van Erp, T. G. M., Potkin, S. G., Brickman, A. M., Rosas, D. H., Yassa, M. A., Silverman, W., Lott, I. T.

10.1101/2020.08.19.257790 — Posted: 2020-08-20

Analysis of heterozygous PRKN variants and copy number variations in Parkinson's disease

Yu, E., Rudakou, U., Krohn, L., Mufti, K., Ruskey, J. A., Asayesh, F., Estiar, M. A., Spiegelman, D., Surface, M., Fahn, S., Waters, C. H., Greenbaum, L., Espay, A. J., Dauvilliers, Y., Dupre, N., Rouleau, G. A., Hassin-Baer, S., Fon, E. A., Alcalay, R. N., Gan-Or, Z.

10.1101/2020.05.07.20072728 — Posted: 2020-08-20

Bayesian inference associates rare KDR variants with specific phenotypes in pulmonary arterial hypertension

Swietlik, E. M., Greene, D., Zhu, N., Megy, K., Cogliano, M., Rajaram, S., Pandya, D., Tilly, T., Lutz, K. A., Welch, C. C. L., Pauciulo, M. W., Southgate, L., Martin, J. M., Treacy, C. M., Penkett, C. J., Stephens, J. C., UK National Cohort Study of Idiopathic and Heritable PAH, , NIHR Bioresource for Translational Research - Rare Diseases, , US PAH Biobank Enrolling Centers' Investigators, , Lawrie, A., Wilkins, M. R., Trembath, R. C., Shen, Y., Wendy, C. K., Swift, A. J., Nichols, W. C., Morrell, N. W., Gräf, S.

10.1101/2019.12.11.871210 — Posted: 2020-08-18

Extracting novel antimicrobial emergence events from scientific literature and medical reports

Mendelsohn, E., Ross, N., White, A. M., Whiting, K., Basaraba, C., Watson Madubuonwu, B., Johnson, E., Dualeh, M., Matson, Z., Dattaray, S., Ezeokoli, N., Kirshenbaum Lieberman, M., Kotcher, J., Maher, S., Zambrana-Torrelio, C., Daszak, P.

10.1101/2020.08.13.20165852 — Posted: 2020-08-15

Evaluation of gait initiation parameters using inertial sensors in Huntington's Disease: Insights into anticipatory postural adjustments and cognitive interference

Desai, R., Fritz, N. E., Muratori, L., Hausdorff, J. M., Quinn, L.

10.1101/2020.08.13.20174235 — Posted: 2020-08-15

Scarless engineering of the Drosophila genome near any site-specific integration site

Feng, S., Lu, S., Grueber, W. B., Mann, R. S.

10.1101/2020.08.13.249656 — Posted: 2020-08-14

Immunoreactive peptide maps of SARS-CoV-2 and other human coronaviruses

Mishra, N., Huang, X., Joshi, S., Guo, C., Ng, J., Thakkar, R., Wu, Y., Dong, X., Li, Q., Pinapati, R., Sullivan, E., Caciula, A., Tokarz, R., Briese, T., Lu, J., Lipkin, W. I.

10.1101/2020.08.13.249953 — Posted: 2020-08-14

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