Channel: Columbia University

This collection includes bioRxiv and medRxiv papers from authors at Columbia University.

4760 Articles

Evolutionary dynamics of FoxQ2 transcription factors across metazoans: A tale of three ancient paralogs

Gattoni, G., Lin, C.-Y., York, J. R., Keitley, D., LaBonne, C., Yu, J.-K., Gillis, A., Benito-Gutierrez, E.

10.1101/2025.04.23.650082 — Posted: 2025-04-24

Mechanistic Insights into Proteomic Mutation-Phenotype Linkages from Tiling Mutagenesis Screens

He, W., Huang, J.-W., Wang, Y., Hayward, S. B., Leuzzi, G., Fu, R., Wang, S., Vaitsiankova, A., Bedford, M. T., Guerois, R., Ciccia, A., Xu, H.

10.1101/2025.04.17.649336 — Posted: 2025-04-23

The Effects of Antidepressants on the Hippocampus: A Meta-Analysis of Public Transcriptional Profiling Data

Geoghegan, E. M., Hagenauer, M. H., Hernandez, E., Espinoza, S., Flandreau, E. I., Nguyen, P. T., Bhuiyan, M. R., Mensch, S., Watson, S. J., Akil, H.

10.1101/2025.04.21.648805 — Posted: 2025-04-23

The gSOS Polygenic Score is Associated with Bone Density and Fracture Risk in Childhood

Mitchell, J. A., Bradfield, J., McCormack, S., Chesi, A., Kalkwarf, H., Lappe, J., Oberfield, S., Duren, D., Shepherd, J., Hankenson, K., Kelly, A., Hakonarson, H., Grant, S. F., Zemel, B.

10.1101/2025.04.22.25325387 — Posted: 2025-04-23

Single Cell Landscape of Sex-specific Drivers of Alzheimers Disease

Wu, Y., Travaglini, K. J., Gabitto, M., Keene, D., Dunn, A., Kaczorowski, C., Harari, O., De Jager, P., Menon, V., Schneider, J. A., Bennett, D. A., Dumitrescu, L., Hohman, T. J.

10.1101/2025.04.18.647076 — Posted: 2025-04-22

Multiple human enhancer RNAs contain long translated open reading frames

Vlasov, P. A., Ogami, K., Valenzuela, E., Kawaguchi, R. K., Jovanovic, M., Manley, J. L.

10.1101/2025.04.18.649583 — Posted: 2025-04-21

A polymeric, PDMS-based large-scale skull replacement suitable for optical and mechanical access for long-term neuronal imaging, electrophysiology, and optogenetics

Takahashi, K., Huis in 't Veld, G. J., Benedetti, D., Wang, J.-Y., Pontes Quero, S., Yuste, R., Pennartz, C. M. A., Olcese, U.

10.1101/2025.04.15.648966 — Posted: 2025-04-20

Genome-wide mapping of mesoscale neuronal RNA organization and condensation

Becker, L. A., Quinodoz, S. A., Comi, T. J., Kimchi, O., Knowles, D. A., Brangwynne, C. P.

10.1101/2025.04.19.649570 — Posted: 2025-04-20

A Translational Neuroscience & Computational Evaluation of a D1R Partial Agonist for Schizophrenia (TRANSCENDS): Rationale and Study Design of a Brain-Based Clinical Trial

Fonteneau, C., Tamayo, Z., Price, A., Pan, L., Afriyie-Agyemang, Y., Agrawal, S., Butler, A., Cail, C., Calkins, M., Chakilam, S., Forselius-Bielen, K., Fram, G., Frazier, A., Gil, R., Govil, P., Gray, D. L., Grinband, J., Gur, R. C., Haubold, N. K., Heffernan, Z., Kegeles, L., Kohler, C., Lin, C., Lu, J., Mayer, M., Pham, P., Perlman, G., Rahmati, M., Ranganathan, M., Santamauro, N. P., Schutte, C. T., Selloni, A., Van Snellenberg, J., Surti, T., Wolf, D. H., Zharyy, C., TRANSCENDS Group, , Abi-Dargham, A., Gur, R. E., Lieberman, J. A., Kantrowitz, J. T., Anticevic, A., Cho, Y. T., Krystal

10.1101/2025.04.18.25326082 — Posted: 2025-04-20

Integrative multi-omics QTL colocalization maps regulatory architecture in aging human brain

Cao, X., Sun, H., Feng, R., Mazumder, R., Najar, C. F. B. A., Li, Y. I., De Jager, P. L., Bennett, D. A., The Alzheimer's Disease Functional Genomics Consortium, , Dey, K. K., Wang, G.

10.1101/2025.04.17.25326042 — Posted: 2025-04-20

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