Channel: Washington University in St. Louis

This collection includes bioRxiv and medRxiv papers from authors at Washington University in St. Louis.

2225 Articles

A circular engineered sortase for interrogating histone H3 in chromatin

Whedon, S. D., Lee, K., Wang, Z. A., Zahn, E., Lu, C., Abeywardana, M. Y., Fairall, L., Nam, E., Dubois-Coyne, S., De Ioannes, P., Sheng, X., Andrei, A., Lundberg, E., Jiang, J., Armache, K.-J. D., Zhao, Y., Schwabe, J. W. R., Wu, M., Garcia, B., Cole, P. A.

10.1101/2024.09.10.612318 — Posted: 2024-09-10

SIRT6 loss causes intervertebral disc degeneration in mice by promoting senescence and SASP status

Ramteke, P., Watson, B., Toci, M., Tran, V., Johnston, S., Tsingas, M., Barve, R., Mitra, R., Loeser, R., Collins, J., Risbud, M.

10.1101/2024.09.09.612072 — Posted: 2024-09-09

The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: a safety study

Tan, G., Huguenard, A. L., Donovan, K. M., Demarest, P., Liu, X., Li, Z., Adamek, M., Lavine, K., Vellimana, A. K., Kummer, T. T., Osbun, J. W., Zipfel, G. J., Brunner, P., Leuthardt, E. C.

10.1101/2024.04.03.24304759 — Posted: 2024-09-08

Lipid-siRNA conjugate accesses a perivascular transport mechanism and achieves widespread and durable knockdown in the central nervous system

Sorets, A., Schwensen, K., Francini, N., Kjar, A., Abdulrahman, A., Shostak, A., Katdare, K., Schoch, K., Cowell, R., Park, J., Ligocki, A., Ford, W., Ventura-Antunes, L., Hoogenboezem, E., Prusky, A., Castleberry, M., Michell, D. L., Miller, T., Vickers, K., Schrag, M., Duvall, C., Lippmann, E.

10.1101/2024.06.09.598079 — Posted: 2024-09-07

A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models

Puray-Chavez, M., Eschbach, J. E., Xia, M., LaPak, K., Zhou, Q., Jasuja, R., Pan, J., Xu, J., Zhou, Z., Mohammed, S., Wang, Q., Lawson, D., Djokic, S., Hou, G., Ding, S., Brody, S. L., Major, M. B., Goldfarb, D., Kutluay, S. B.

10.1101/2024.01.07.574522 — Posted: 2024-09-06

The small MAF transcription factor MAFG co-opts MITF to promote melanoma progression

Vera, O., Martinez, M., Soto-Vargas, Z., Wang, K., Xu, X., Ruiz-Buceta, S., Mecozzi, N., Chadourne, M., Posorske, B., Angarita, A., Bok, I., Liu, Q., Murikipudi, H., Kim, Y., Messina, J. L., Tsai, K. Y., Major, M., Lau, E. K., Yu, X., Ibanez-de-Caceres, I., Karreth, F. A.

10.1101/2024.09.03.611024 — Posted: 2024-09-06

Structural Basis for Dimerization and Activation of UvrD-family Helicases

Chadda, A., Nguyen, B., Lohman, T. M., Galburt, E. A.

10.1101/2024.09.05.611425 — Posted: 2024-09-06

DIFFERENTIAL CONTRIBUTIONS OF THE SPECTRO-TEMPORAL AND VOCAL CHARACTERISTICS OF AUDITORY PSEUDOWORDS TO MULTIPLE SOUND-SYMBOLIC MAPPINGS

Lacey, S., Matthews, K. L., Hoffmann, A. M., Sathian, K., Nygaard, L. C.

10.1101/2024.09.03.610973 — Posted: 2024-09-05

A Large-Scale Genome-Wide Gene-Sleep Interaction Study in 732,564 Participants Identifies Lipid Loci Explaining Sleep-Associated Lipid Disturbances

Noordam, R., Wang, W., Nagarajan, P., Wang, H., Brown, M. R., Bentley, A. R., Hui, Q., Kraja, A. T., Morrison, J. L., O'Connel, J. R., Lee, S., Schwander, K., Bartz, T. M., de las Fuentes, L., Feitosa, M. F., Guo, X., Hanfei, X., Harris, S. E., Huang, Z., Kals, M., Lefevre, C., Mangino, M., Milaneschi, Y., van der Most, P., Pacheco, N. L., Palmer, N. D., Rao, V., Rauramaa, R., Sun, Q., Tabara, Y., Vojinovic, D., Wang, Y., Weiss, S., Yang, Q., Zhao, W., Zhu, W., Abu Yusuf Ansari, M., Aschard, H., Anugu, P., Assimes, T. L., Attia, J., Baker, L. D., Ballantyne, C., Bazzano, L., Boerwinkle, E., Ca

10.1101/2024.09.02.24312466 — Posted: 2024-09-04

A Machine Learning Approach to Predict Cognitive Decline in Alzheimer's Disease Clinical Trials

Nallapu, B. T., Petersen,, K. K., Qian,, T., Demirsoy,, I., Ghanbarian,, E., Davatzikos,, C., Lipton,, R. B., Ezzati,, A., For the Alzheimers Disease Neuroimaging Initiative

10.1101/2024.09.03.24312481 — Posted: 2024-09-04

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