Channel: Washington University in St. Louis

This collection includes bioRxiv and medRxiv papers from authors at Washington University in St. Louis.

3000 Articles

Replicable generation of rhesus macaque iPSCs for in vitro modeling of genetic frontotemporal dementia

Colwell, J., Maufort, J. P., Williams, K. M., Makulec, A. T., Fiorentino, M. V., Metzger, J. M., Simmons, H. A., Basu, P., Malicki, K. B., Karch, C., Marsh, J. A., Emborg, M. E., Schmidt, J. K.

10.64898/2026.03.17.712482 — Posted: 2026-03-18

High-channel-count neural recording and stimulation platform with 5,376 simultaneous recording channels

Fan, Y., Ma, Y., Zolotavin, P., Topalli, G., Wang, W., Karlsson, M., Karlsson, M., Luan, L., Xie, C., Chi, T.

10.64898/2026.03.13.709972 — Posted: 2026-03-17

C9ORF72-derived polyGR polypeptides disrupt passive nucleocytoplasmic transport by tuning protein affinity for the nuclear pore barrier

Solomon, D. A., Emenecker, R. J., Salcher-Konrad, M.-T., Konstantinidou, S. M., Houghton, O. H., Wycherley, E., Lee, S., O'Brien, N. L., Alcalde, J., Lourenco Cabaco, I., Ruepp, M.-D., Schmidt, H. B., Holehouse, A. S., Mizielinska, S.

10.64898/2026.03.16.711670 — Posted: 2026-03-17

Distinguishing near- versus off-critical phase behaviors of intrinsically disordered proteins

Mitra, G., Ghosh, S., Ruff, K. M., Zhang, R., Chauhan, G., Pappu, R. V.

10.64898/2025.12.01.691696 — Posted: 2026-03-16

Predicting future cognitive impairment in preclinical Alzheimer's disease using amyloid PET and MRI: a multisite machine learning study

Yang, B., Earnest, T., Bilgel, M., Albert, M. S., Johnson, S. C., Davatzikos, C., Erus, G., Masters, C. L., Resnick, S. M., Miller, M. I., Bakker, A., Morris, J. C., Benzinger, T. L., Gordon, B. A., Sotiras, A., for the Alzheimer's Disease Neuroimaging Initiative, , for the Preclinical Alzheimer's Disease Consortium

10.1101/2025.10.15.25337507 — Posted: 2026-03-16

SLC33A1 exports oxidized glutathione to maintain endoplasmic reticulum redox homeostasis

Liu, S., Gad, M., Li, C., Cho, K., Liu, Y., Wangdu, K., Belay, V., Millet, A., Kojima, H., Sanford, H., Wolk, M., Urnavicius, L., Fedorova, M., Patti, G. J., Vinogradova, E. V., Hite, R. K., Birsoy, K.

10.64898/2026.02.01.703113 — Posted: 2026-03-16

Neural mechanisms of handedness for precision drawing: hand-dependent engagement of cortical networks for bimanual control and tool use

Kapil, N., Kim, T., Gassass, S., Zhou, R., Carter, A. R., Dobbins, I. G., Liu, L., McAvoy, M. P., Wheelock, M. D., Wang, Y., Brogan, D. M., Dy, C. J., Susan, M. E., Philip, B. A.

10.1101/2025.11.18.689091 — Posted: 2026-03-16

Tatton-Brown-Rahman-Syndrome-associated DNMT3A mutations de-repress cortical interneuron differentiation to disrupt neuronal network function

Chapman, G., Determan, J., Edwards, J. R., Batool, F., Huettner, J. E., Prakasam, R., Crump, S., Law, T. E., Jetter, H., Gabel, H. W., Kroll, K. L.

10.1101/2025.06.24.661324 — Posted: 2026-03-16

Bias and Variance of Adjusting for Instruments

Hripcsak, G., Anand, T., Chen, H. Y., Zhang, L., Chen, Y., Suchard, M. A., Ryan, P. B., Schuemie, M. J.

10.64898/2026.03.13.26348328 — Posted: 2026-03-15

TMEM106B mediates ACE2-independent replication of the SARS-CoV-2 S-E484D variant in airway-derived cell models

Xia, M., Wang, Q., Puray-Chavez, M., LaPak, K., Palakurty, S., Liu, Z., Cornejo Pontelli, M., Hui, S., Fremont, D. H., Diamond, M. S., Whelan, S. P. J., Major, M. B., Goldfarb, D., Kutluay, S. B.

10.64898/2026.03.14.711762 — Posted: 2026-03-15

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