Channel: Washington University in St. Louis

This collection includes bioRxiv and medRxiv papers from authors at Washington University in St. Louis.

2911 Articles

Astrocytic Cholesterol Fine-Tunes the Balance of Different Modes of Synaptic Exo- and Endocytosis

Myeong, J., Klyachko, V.

10.64898/2025.12.28.696787 — Posted: 2026-02-07

SWI/SNF nuclear foci scaffold peripheral gene hubs for circadian chromatin control

Chen, Q., Yuan, Y., Clark, D., Yadlapalli, S.

10.64898/2026.02.03.703661 — Posted: 2026-02-06

Automated Ventricle Assessment via Three-dimensional Anatomical Reconstruction (AVA-TAR): a computational toolkit for autonomous lateral ventricle assessment in preclinical hydrocephalus models

Chakladar, S., Pan, S., Limbrick, O., Pandey, M., Halupnik, G. L., Zhao, A., Mahjoub, M. R., Quirk, J. D., Nazeri, A., Strahle, J. M.

10.64898/2026.02.02.703412 — Posted: 2026-02-05

Non-invasive genomic sampling uncovers novel connectivities and origins of confiscated gorillas

Ruiz-Gartzia, I., Pawar, H., Alvarez-Estape, M., Orkin, J. D., Alentorn-Moron, P., Ruibal-Puertas, S., Ostridge, H. J., Fontsere, C., Cuadros-Espinoza, S., Gilardi, K., Nziza, J., Muvunyi, R., Maloueki, U., Caillaud, D., Iyer, N., Ngobobo-As-Ibungu, U., Binyinyi, E., Akomo-Okoue, E. F., Basabose, A. K., Sebulimbwa, K., Ngomanda, A., Yamagiwa, J., Inoue-Murayama, M., Takenoshita, Y., Fujita, S., Pafco, B., Fuh, T., Tagg, N., Mbohli, D., Ayimisin, E. A., Bailey, E., Bessone, M., Deschner, T., Dieguez, P., Dilambaka, E., Dunn, A., Granjon, A.-C., Head, J., Hermans, V., Imong, I., Jeffery, K. J.

10.64898/2026.02.03.701083 — Posted: 2026-02-05

Disentangling Environmental and Genetic Influences on the Association Between Childhood Bullying Victimization and Psychotic-Like Experiences

Karcher, N. R., Barch, D. M., Oh, H., Paul, S., Osborne, K. J., Baranger, D. A., Bogdan, R., Agrawal, A., Johnson, E. C.

10.64898/2026.02.04.26345591 — Posted: 2026-02-05

Shared Pathogenic Pathways Between REM Sleep Behavior Disorder and Neurodegenerative and Psychiatric Disorders

Zhang, Z., Somerville, E. N., Fang, Z.-H., Liu, L., Asayesh, F., Ahmad, J., Amiri, S., Teferra, M., Dodet, P., Arnulf, I., Hu, M. T. M., Desautels, A., Dauvilliers, Y., Aktan-Süzgün, M., Ibrahim, A., Stefani, A., Högl, B., Gaig, C., Montini, A., Maya, G., Iranzo, A., Serradell, M., Gigli, G. L., Valente, M., Janes, F., Bernardini, A., Sonka, K., Kemlink, D., Dusek, P., Sommerauer, M., Röttgen, S., Figorilli, M., Puligheddu, M., Mollenhauer, B., Trenkwalder, C., Sixel-Doring, F., Plazzi, G., Biscarini, F., Antelmi, E., Cochen De Cock, V., Terzaghi, M., Fiamingo, G., Heidbreder, A., Ferini-S

10.64898/2026.02.05.26345599 — Posted: 2026-02-05

Multimodal profiling of human sensory neurons links electrical properties to transcriptional identity

Yi, J., Yang, L., Widman, A. J., Toliver, A., Bertels, Z., del Rosario, J. S., Dourson, A. J., Gupta, P., Kumar, R., Li, J.-N., Payne, M., Slivicki, R. A., Mwirigi, J. M., Chamessian, A., Kothapalli, K., Moore, G., Lemen, J., Copits, B. A., Gereau, R. W., PRECISION Human Pain Network

10.1101/2025.03.25.645367 — Posted: 2026-02-05

Trans-eQTLs reveal the architecture of human gene regulatory networks

Warmerdam, C. A. R., Westra, H.-J., van der Graaf, A., Bonder, M. J., Deelen, P., van Lieshout, T., Landman, A. J., Jesse, M., Strober, B. J., Boltz, T., Lapinska, S., Nagpal, S., Xie, M., Tay, D., Kirsten, H., Naeem, H., Raghavan, V., Farzeen, A., Teumer, A., Fave, M.-J., Persyn, E., Tokolyi, A., Pool, R., Hottenga, J. J., Rodriguez, R. D., Rivas-Torrubia, M., Hamal Mishra, B., Pierce, B., Tong, L., Wang, Q. S., Hasegawa, T., Chhetri, S. B., Dutta, D., Weiss, S., Dupuis, T., Lyytikäinen, L.-P., Mishra, P. P., Wood, A. R., Burnham, K. L., Wen, J., Cheruiyot, E., Boahen, C. K., Jansen, R., Kro

10.64898/2026.02.04.26343575 — Posted: 2026-02-05

Metabolic Flexibility and Energy Substrate Utilization Regulate Contractility in the Human Myometrium

Prifti, K. K., Dave, R. M., Mitchum, K. T., Rich, J. L., Gill, R. M., Mbadhi, M. N., Frolova, A. I.

10.64898/2026.02.02.702681 — Posted: 2026-02-04

The orientation of cholesterol's hydroxyl group affects its membrane dynamics and intracellular transport

Lauritsen, L., Pauli, A. T., Larsen, M. P. W., Reinholdt, P., Scheidt, H. A., Xu, Y., Covey, D. F., Depta, L., Bryce-Rogers, H. P., Laraia, L., Kongsted, J., Wüstner, D.

10.64898/2026.02.02.703222 — Posted: 2026-02-04

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