Channel: University of California, San Francisco

This collection includes bioRxiv and medRxiv papers from authors at University of California, San Francisco.

2875 Articles

Multi-omic phenotyping of iPSC-derived neurons harboring the MAPT V337M mutation reveals tau hypophosphorylation and perturbed axon morphology pathways

Mohl, G. A., Dixon, G., Marzette, E., McKetney, J., Samelson, A. J., Pereda Serras, C., Jin, J., Ariqat, N., Li, A., Boggess, S. C., Swaney, D. L., Kampmann, M.

10.1101/2024.06.04.597496 — Posted: 2025-09-09

A Low-Burden Sleep Foundation Model Built on Respiratory and Heartbeat Signals from 780,000+ Hours of Multi-Ethnic Sleep Recordings

Nie, G., Chen, X., Wang, Y., Chen, J., Shi, Y., Zhong, J., Huang, W., Jin, Z., Lei, F., Wang, L., Zhao, R., Zhang, C., Chen, K., Lv, D., Chen, W., Yi, H., Tang, X., Yin, S., Li, Y., Hong, S., Leng, Y.

10.1101/2025.09.06.25335216 — Posted: 2025-09-09

De novo design of semisynthetic protein nanopores

Schnaider, L., Hatstat, A. K., Scott, A. J., Tan, S. K., Hambley, R. G., Dawson, W. M., Griffiths, R. C., Kormos, R. C., Melo, A. A., Tse, E., Polizzi, N. C., Wallace, E. J., Merz, G. E., DeGrado, W. F.

10.1101/2025.09.08.674823 — Posted: 2025-09-08

Decoding subphenotypes in electronic medical records within late-onset Alzheimer's disease reveals heterogeneity and sex-specific differences

Katsuhara, Y., Khan, U., Miller, Z. A., Allen, I. E., Oskotsky, T. T., Sirota, M., Tang, A. S.

10.1101/2025.04.24.25326306 — Posted: 2025-09-08

Placental Abnormalities of Malperfusion, Inflammation, and Meconium Precede Persistent Pulmonary Hypertension of the Newborn

Tsoi, S. M., Gasper, C., Maltepe, E., Chidboy, M. A., Ozarslan, N., Blauvelt, C. A., Buarpung, S., Cheung, S., Steurer, M., Keller, R. L., Fineman, J. R., Gaw, S. L.

10.1101/2025.09.05.25335190 — Posted: 2025-09-08

Targeting p16INK4a reverses alveolar epithelial cell dysfunction and induces lung regeneration in emphysema

Ribeiro Baptista, B., Toigo, M., Justeau, G., Abou-atmeh, P., De Freitas Castro, T., Zysman, M., Thiebaut De Menonville, C., Audureau, E., Schnyder, K., Wang, H., Hu, Y., Koenigshoff, M., Lanone, S., Chabot, F., Zana-Taieb, E., Jourdan Le Saux, C., Lehmann, M., Derumeaux, G., Boczkowski, J., Gote-Schniering, J., Boyer, L.

10.1101/2025.09.05.674489 — Posted: 2025-09-07

Design considerations for incorporating serological monitoring into trachoma prevalence surveys

Kamau, E., Gass, K., Harding-Esch, E. M., Saboya Diaz, M. I., Ante-Testard, P. A., Kello, A. B., Bailey, R. L., Fornace, K., Solomon, A. W., Nash, S. D., Arnold, B. F., Global Trachoma Serosurveillance Study Group

10.1101/2025.09.05.25334960 — Posted: 2025-09-07

BOGO: A Proteome-Wide Gene Overexpression Platform for Discovering Rational Cancer Combination Therapies

Jo, K. B., Alruwaili, M. M., Kim, D.-E., Koh, Y., Kim, H., You, K., Kim, J.-S., Sane, S., Guo, Y., Wright, J. P., Lim, H. J., Naranjo, M. N., Cote, A. G., Roth, F. P., Hill, D. E., Choi, J.-H., Lee, H., Matreyek, K. A., Farh, K. K.- H., Park, J.-E., Kim, H., Bakin, A. V., Kim, D.-K.

10.1101/2025.09.02.673780 — Posted: 2025-09-07

RT2C: Predicting Time to New Dental Caries Using a Recurrent Neural Network Model Trained on Multi-Site Longitudinal Structured Dental Data

Liu, X., Kookal, K. K., Brandon, R., Rindal, D. B., Mullins, J., White, J. M., Walji, M. F., Rasmy, L.

10.1101/2025.09.03.25334405 — Posted: 2025-09-05

Spatial Single-Cell Atlas Reveals KSHV-Driven Broad Cellular Reprogramming, Progenitor Expansion, Immune and Vascular Remodeling in Kaposi's Sarcoma

Meng, W., Das, A., Sinha, H., Naous, R., Bracci, P., McGrath, M., Huang, Y., Gao, S.-J.

10.1101/2025.09.01.673567 — Posted: 2025-09-05

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