Channel: University of California, San Francisco

This collection includes bioRxiv and medRxiv papers from authors at University of California, San Francisco.

3152 Articles

Human genetics implicates a BACH2-NRF2 axis in fetal hemoglobin activation

Guo, C.-J., Arora, U. P., Xu, W., Cheng, X., Cato, L. D., Li, R., Lu, H. Y., Lee, A. J., Yu, F., Agarwal, G., Lyu, P., Ye, T., Antoszewski, M., Wissman, M., Mkumbe, B. S., Ekwattanakit, S., Deelen, P., Mwita, L., Sangeda, R. Z., Suksangpleng, T., Riolueang, S., Bronson, P. G., Paul, D. S., Kawabata, E., Astle, W. J., Aguet, F., Ardlie, K., Lopez de Lapuente Portilla, A., Kang, G., Zhang, Y., Nouraie, S. M., Gordeuk, V. R., Gladwin, M. T., Garrett, M. E., Ashley-Koch, A., Telen, M. J., Custer, B., Kelly, S., DINARDO, C., Sabino, E. C., Loureiro, P., Carneiro-Proietti, A. B., Maximo, C., NHLBI T

10.1101/2023.03.24.23287659 — Posted: 2025-12-27

Seasonally varying effects of improved water, sanitation and handwashing interventions on Giardia infection in Bangladesh

Ante-Testard, P. A., Rerolle, F., Rahman, M., Haque, R., Das, S., Parvez, S. M., Ercumen, A., Lin, A., Luby, S. P., Benmarhnia, T., Arnold, B. F.

10.64898/2025.12.17.25342505 — Posted: 2025-12-27

When AI Meets the FDA: An Evaluation of Large Language Models Performance in Regulatory and Clinical Trial Data Extraction, Synthesis, and Analysis

Bukhari, K., Rodriguez-Monguio, R., Lopez-Bermudez, B., Yamaki, J., Beuttler, R., Ong, J. C. L., Brown, L. M., Seoane-Vazquez, E.

10.64898/2025.12.22.25342875 — Posted: 2025-12-27

Costs associated with increasing numbers of Medicare beneficiaries with HIV aged 65 years and older from 2026 to 2035

Hyle, E. P., Ang, L., Luu, G., Kasaie, P., Dai, D., Koiso, S., Phelan, J., Ebem, F., Duggan, C., Humes, E., Sax, P. E., Gerace, L., Giardina, J., Orav, E. J., Neilan, A. M., Pandya, A., Figueroa, J. F., Althoff, K. N., Freedberg, K. A.

10.64898/2025.12.19.25342703 — Posted: 2025-12-27

Aging increases ovarian cancer growth, metastasis and immunosuppression that can be alleviated by inhibiting hedgehog signaling

Kumari, A., Elbahoty, M. H., Rajkarnikar, R., Sureja, K., Monavarian, M., Quintero, L. M., Fuh, K., Tyrrell, D. J., Shevde, L. A., Margaroli, C., Mythreye, K.

10.64898/2025.12.23.695206 — Posted: 2025-12-27

Cerebral Cortical Reorganization After Intracerebral Hemorrhage in Children

Choi, H. L., Mahuvakar, S., Schollenberger, J., Shuere, R., Sadikov, A., Cai, L. T., Mrakotsky, C., Nesbit, K., Hess, L. G., Kim, H., Saloner, D. A., Fox, C. K., Roland, J. L., Fullerton, H. J., Mukherjee, P., UCSF AHA Bugher Hemorrhagic Stroke Research Group

10.64898/2025.12.19.25341480 — Posted: 2025-12-27

Dose-dependent NFI regulation of progenitor lifespan and output underlying human neocortical malformation

Zhang, Q., Yuan, G., Albizzati, E., Yang, J., Zhao, Z., Yu, X., Chang, X., Lee, C. H., Du, H., Lao, Z., Krishnamurthy, A., Zhang, X., Lv, X., Tang, X., Hu, S., Chi, Y., Ma, J., Gronostajski, R. M., Richards, L. J., Zhang, J., Joyner, A. L., Tchieu, J., Li, Y., Shi, S.-H.

10.64898/2025.12.27.696675 — Posted: 2025-12-27

Shared genetic architecture of brain age gap across 30 cohorts worldwide

Baltramonaityte, V., Jawinski, P., Staginnus, M., Shahisavandi, M., Kovacs, B. Z., Schuurmans, I. K., Constantinides, C., Hariri, A. R., Teumer, A., Rodrigue, A. L., Tsuchida, A., Manzouri, A., Karuk, A., Fuertjes, A. E., Lella, A., Knodt, A. R., Juellig, A., Caspi, A., Crespo-Facorro, B., Penninx, B. W., Lavebratt, C., Lochner, C., Yasuda, C. L., Alnaes, D., Stein, D. J., Mathalon, D. H., Glahn, D. C., Klose, D., Kiltschewskij, D. J., Pomarol-Clotet, E., Bruxel, E. M., Crivello, F., Cendes, F., Davies, G., Salum, G. A., Grabe, H. J., Zar, H. J., Tiemeier, H., Voelzke, H., Lemaitre, H., Lopes-

10.64898/2025.12.23.25342890 — Posted: 2025-12-27

Mammalian metaphase kinetochores are elastic and require condensin for robust structure and function

Tran, V. M., Tao, J., Rux, C. J., Gomez Siu, D., Rosas Salvans, M., Dumont, S.

10.64898/2025.12.23.696255 — Posted: 2025-12-25

Daple-FLT3 (CCDC88C-FLT3) gene fusion requires the coiled-coil domain for maximal activation and pericentrosomal localization

Kao, D., Acquazzino, M., Ibarra, A., Valenzuela, E., Mai, H., Aguilar, K., Stieglitz, E., Ear, J.

10.1101/2025.09.25.678166 — Posted: 2025-12-25

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