Channel: University of California, San Francisco

This collection includes bioRxiv and medRxiv papers from authors at University of California, San Francisco.

3093 Articles

Methylation Clocks Do Not Predict Age or Alzheimer's Disease Risk Across Genetically Admixed Individuals

Cruz-Gonzalez, S., Okpala, O., Gu, E., Gomez, L., Mews, M., Vance, J. M., Cuccaro, M. L., Cornejo-Olivas, M. R., Feliciano-Astacio, B. E., Byrd, G. S., Haines, J. L., Pericak-Vance, M. A., Griswold, A. J., Bush, W. S., Capra, J. A.

10.1101/2024.10.16.618588 — Posted: 2025-12-01

Interrogating the Regulatory Function of HAQERs during Human Cortical Development

Abeykoon, Y., Dzikowski, N., Luo, Y., Sinniah, E., Weaver, S., Pavlovic, B. J., Wallace, J. L., Mangan, R. J., Lowe, C. B., Pollen, A. A.

10.1101/2025.11.30.691411 — Posted: 2025-12-01

Bacterial strains in the human gut associate with host physiology

Shoer, S., Godneva, A., Weinberger, A., Pollard, K. S., Pilpel, Y., Segal, E.

10.1101/2025.11.30.691432 — Posted: 2025-12-01

HDL-associated phosphatidylserine blunts myeloid activation and protects from atherosclerosis

Bernal, A., Hamid, A., Grao-Roldan, C., Scarpa, A., Sanchez, I., Nicolas-Avila, J. A., Pena-Couso, L., Yaghmour, M. H., Benguria, A., Rosado, A., Sanchez, L., Torroja, C., Dopazo, A., Sanchez-Cabo, F., Hidalgo, A., Senders, M. L., van Leent, M. M. T., Seep, L., Hasenauer, J., Placek, K., Thiele, C., Netea, M. G., Mulder, W. J. M., Riksen, N. P., Perez-Medina, C.

10.1101/2025.11.26.689708 — Posted: 2025-11-30

Uncovering senescent fibroblast heterogeneity connects DNA damage response to idiopathic pulmonary fibrosis

Hughes, J.-W. B., Pujari, A., Sandholm, A., Croll, D., Monk, L. B., Joshua, I., Butterfield, R., Horton, C., Schneider, K., Senchyna, F., Brown, I., Coelho, A. L., Ho, T.-C., Deguchi, H., Le Saux, C. J., Deinhardt-Emmer, S., Ellerby, L. M., Vitari, A., Furman, D., Hogoboam, C. M., Laslavic, A., Desprez, P.-Y., Quarta, M., Campisi, J.

10.1101/2025.11.26.690792 — Posted: 2025-11-30

Spatial Transcriptomics Reveals CXCL12+ Fibroblasts as Central Immune Organizers through CXCR4 Signaling in Abdominal Aortic Aneurysm

Levy-Lambert, D., Ramirez, J. L., Shaikh, S., De Jeronimo Diaz, C., Huang, A. G., Combes, A., Fragiadakis, G., Fidler, T., Oskowitz, A.

10.1101/2025.11.24.690328 — Posted: 2025-11-29

Hippo signaling differentially regulates distal progenitor subpopulations and their transitional states to construct the mammalian lungs

Zhang, K., Basak, M., Zaher, Y., Yao, E., Wang, S.-A., Aung, T., Chuang, P.-T.

10.1101/2025.10.28.684989 — Posted: 2025-11-29

Neuronal APOE4 alone is sufficient to drive tau pathology, neurodegeneration, and neuroinflammation in an Alzheimer's disease mouse model

Blumenfeld, J., Li, Y., Kim, M. J., Yip, O., Yao, L., De Leon, S., Fulthorpe, R., Shostak, D., Platow, Z., Suan, K., Hao, Y., Koutsodendris, N., Ellis, C., Nguyen, J., Huang, Y.

10.1101/2025.11.25.690488 — Posted: 2025-11-29

Genome x Environment analysis of Sudden Unexpected Infant Death unveils etiologic heterogeneity and strong cannabis and genetic disease risks

Kingsmore, S. F., Bandoli, G., Helbling, D. C., Baer, R., Blincow, E., Cao, B., Frise, E., Heinen, A., Jelliffe-Pawlowski, L., Sanford Kobayashi, E., Van Der Kraan, L., Kwon, H., Lavy, R., Moore, B., Oh, D., Oltman, S., Ontiveros, E., Protopsaltis, L., Yandell, M., Chambers, C. D.

10.1101/2025.11.26.25341098 — Posted: 2025-11-28

Dynamic PET imaging predicts broadly neutralizing antibody distribution and HIV prevention efficacy.

Chu, D., Kuo-Esser, L., Beckford-Vera, D., Flavell, R., Seo, Y., VanBrocklin, H., Henrich, T., Deitchman, A. N.

10.1101/2025.11.26.25341044 — Posted: 2025-11-28

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