Channel: University of California, San Francisco

This collection includes bioRxiv and medRxiv papers from authors at University of California, San Francisco.

3177 Articles

Neuronal APOE4 reduction with an APOE-I3-targeting ASO protects against neurodegeneration and neuroinflammation in an Alzheimer's disease mouse model

Yip, O., Yao, L., Blumenfeld, J., Kim, M. J., Shostak, D., Platow, Z., Suan, K., Li, Y., Ellis, C., An, A., Hao, Y., Xu, Q., De Leon, S., Nguyen, J., Huang, Y.

10.64898/2025.12.10.693468 — Posted: 2025-12-13

MechanoMR microparticle (M3) sensors reveal dynamic stress loading as a driver of epithelial-mesenchymal transition

An, M., Yu, R., Lin, A., Jang, J., Ohk, J., Kim, Y.-J., Jung, H., Kwak, M., Jun, Y.-w., Cheon, J.

10.64898/2025.12.10.693598 — Posted: 2025-12-13

Genome-wide analysis of anterior-posterior mRNA regionalization in Stentor coeruleus reveals a role for the microtubule cytoskeleton

Albright, A. R., Yan, C., Angeles-Albores, D., Hudnall, Y., Makushok, T., Allen-Henderson, J., Marshall, W. F.

10.1101/2023.01.09.523364 — Posted: 2025-12-13

Poorer physical function is associated with elevated spatial entropy in the aging brain network landscape

McIntyre, C. C., ODonnell, S. M., Lyday, R. G., Burdette, J. H., Cummings, S. R., Kritchevsky, S. B., Laurienti, P. J.

10.64898/2025.12.09.693258 — Posted: 2025-12-12

Mapping the circulating proteome across neurodegeneration: A harmonized, consortium-scale framework for uncovering molecular pathophysiology

Finney, C. A., An, L., Winchester, L. M., Vogel, J., Wilkins, H. M., Burns, J. M., Swerdlow, R. H., Slawson, C., Rothstein, J. D., Global Neurodegeneration Proteomics Consortium, , Lutz, M. W., Saloner, R., Shvetcov, A.

10.64898/2025.12.09.693329 — Posted: 2025-12-12

DE NOVO VARIANTS IN THE POLY(RC)-BINDING PROTEIN GENE PCBP1 CAUSE A NEURODEVELOPMENTAL DISORDER

Deb, W., Besnard, T., Desprez, F., Cogne, B., Do Souto Ferreira, L., Vignard, V., Marouillat, S., Januel, L., Gorokhova, S., Busa, T., Morel, V., Dauriat, B., Desportes, V., Slavotinek, A. M., An, Y., Lee, H., Hary, J., Kannu, P., Athey, T. B., van de Laar, I. M. B. H., van Slegtenhorst, M. A., Dickson, P., Muir, A. M., Buchert, R., Haack, T. B., Imort, D., Sousa, S. B., Xavier, B., Almeida, P. M., Rogac, M., Peterlin, B., Kaspar, S., Netzer, C., Zempel, H., Towne, M. C., Ladda, R. L., Sell, S. S., Gawlinski, P., Song, X., Wiszniewski, W., Calame, D. G., Posey, J. E., Ebstein, F., Lupski, J. R

10.64898/2025.12.11.25341975 — Posted: 2025-12-12

Bifunctional transcriptional effector domains control gene expression pulses in an occupancy-dependent manner

Andrews, C. J., Costa, E. J., Janer Carattini, G. L., DelRosso, N. V., Fujimori, T., Shimasawa, M., Bintu, L.

10.64898/2025.12.10.693551 — Posted: 2025-12-12

BCGNet: An AI Model Trained on 600K Hours of Sleep Data for a Novel Under-Pillow Contactless Monitoring Device

Chen, S., Chen, X., Huang, W., Lei, F., Shan, C., Jin, Z., Shi, Y., Wang, Y., Zhao, R., Xu, X., Lv, D., Li, Y., Pan, S., Chiang, A., Westover, B., Hong, S., Zhang, C., Yin, S., Liu, C.-f., Yi, H., Tang, X., Leng, Y.

10.1101/2025.08.23.25334218 — Posted: 2025-12-12

Alveolar Type II Cell-derived MMP1high basal cells promote destructive microcysts in idiopathic pulmonary fibrosis.

Garakani, K., Brumwell, A. N., Toigo, M., Jacob, A., Wei, Y., Ho, T. C., Wolters, P., Matthay, M. A., Volk, R. F., Zaro, B. W., Iantorno, S. A., Berhan, A., Sheppard, D. W., Auyeung, V. C., Jourdan Le Saux, C. C., Chapman, H. A.

10.64898/2025.12.08.693033 — Posted: 2025-12-11

Activation of cannabinoid receptor CB1 leads to aberrant myelination in development

Miramontes, T. G., Hamling, K. R., Doan, R. A., Singh, S., Collins, H. Y., Emery, B., Call, C. L., Monk, K.

10.64898/2025.12.10.693544 — Posted: 2025-12-11

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