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1,146 Reviews — EMBO Press — All Subjects

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Small molecule inhibitors and a kinase-dead expressing mouse model demonstrate that the kinase activity of Chk1 is essential for mouse embryos and cancer cells
Muralidharan, S. V., Nilsson, L. M., Lindberg, M. F., Nilsson, J. A.
10.1101/2020.01.21.913467 — Posted: 2020-01-21 — Discussion: 2020-07-15  EMBO Press
PTPN2 deletion in T cells promotes anti-tumour immunity and CAR T cell efficacy in solid tumours
Wiede, F., Lu, K.-H., Du, X., Liang, S., Hochheiser, K., Dodd, G., Goh, P., Kearny, C., Meyran, D., Beavis, P., Henderson, M., Park, S. L., Waithman, J., Zhang, S., Zhang, Z.-Y., Oliaro, J., Gebhardt, T., Darcy, P. K., Tiganis, T.
10.1101/757419 — Posted: 2019-09-05 — Discussion: 2020-07-15  EMBO Press
Cyclin B1 scaffolds MAD1 at the corona to activate the spindle assembly checkpoint
Allan, L. A., Reis, M., Liu, Y., Huis in 't Veld, P., Kops, G. J., Musacchio, A., Saurin, A. T.
10.1101/726224 — Posted: 2019-08-05 — Discussion: 2020-07-15  EMBO Press
CRISPR-TAPE: protein-centric CRISPR guide design for targeted proteome engineering
Anderson, D. P., Benns, H. J., Tate, E. W., Child, M. A.
10.1101/2020.02.26.965889 — Posted: 2020-02-26 — Discussion: 2020-07-15  EMBO Press
Dynamic interactions of lymphatic vessels at the hair follicle stem cell niche during hair regeneration
Pena-Jimenez, D., Fontenete, S., Megias, D., Fustero-Torre, C., Grana-Castro, O., Castellana, D., Loewe, R., Perez-Moreno, M.
10.1101/548768 — Posted: 2019-02-13 — Discussion: 2020-07-15  EMBO Press
ESCRT machinery mediates selective microautophagy of endoplasmic reticulum
Schaefer, J., Schessner, J., Bircham, P., Tsuji, T., Funaya, C., Schaeff, K., Ruffini, G., Papagiannidis, D., Knop, M., Fujimoto, T., Schuck, S.
10.1101/661306 — Posted: 2019-06-05 — Discussion: 2020-07-15  EMBO Press
Control of the Endo-Lysosome Homeostasis by the Paracaspase MALT1 regulates Glioma Cell Survival
Jacobs, K. A., Andre-Gregoire, G., Maghe, C., Li, Y., Thys, A., Harford-Wright, E., Trillet, K., Douanne, T., Frenel, J.-S., Bidere, N., Gavard, J.
10.1101/582221 — Posted: 2019-03-23 — Discussion: 2020-07-15  EMBO Press
Machine characterization of rat toxin responses identifies disease states, tolerance mechanisms and organ to whole-body communication
Shimada, K., Mitchison, T.
10.1101/322446 — Posted: 2018-05-28 — Discussion: 2020-07-15  EMBO Press
EZH2 co-opts gain-of-function p53 mutants to promote cancer growth and metastasis
Zhao, Y., Ding, L., Wang, D., Ye, Z., Pan, Y., Ma, L., Coleman, R., Coleman, I., Karnes, R. J., Zhang, J., Nelson, P. S., Wang, L., Zhu, R., Huang, H.
10.1101/298737 — Posted: 2018-04-10 — Discussion: 2020-07-15  EMBO Press
Actin accumulates nesprin-2 at the front of the nucleus during confined cell migration
Davidson, P. M., Battistella, A., Dejardin, T., Betz, T., Plastino, J., Cadot, B., Borghi, N., Sykes, C.
10.1101/713982 — Posted: 2019-07-24 — Discussion: 2020-07-15  EMBO Press

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