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1,205 Reviews — EMBO Press — All Subjects

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The innate immune DNA sensor cGAS is a negative regulator of DNA repair hence promotes genome instability and cell death
Jiang, H., Panda, S., Xue, X., Liang, F., Sung, P., Gekara, N. O.
10.1101/465401 — Posted: 2018-11-08 — Discussion: 2020-10-06  EMBO Press
Enzymatic degradation of RNA causes widespread protein aggregation in cell and tissue lysates
Aarum, J., Cabrera, C., Jones, T., Rajendran, S., Adiutori, R., Giovannoni, G., Barnes, M., Malaspina, A., Sheer, D.
10.1101/841577 — Posted: 2019-11-17 — Discussion: 2020-10-06  EMBO Press
Cell cycle dynamics of lamina associated DNA
van Schaik, T., Vos, M., Peric-Hupkes, D., van Steensel, B.
10.1101/2019.12.19.881979 — Posted: 2019-12-19 — Discussion: 2020-10-06  EMBO Press
Levels of histidine-rich glycoprotein in human blood predict accelerated aging
Hong, M.-G., Dodig-Crnkovic, T., Chen, X., Drobin, K., Lee, W., Sjöberg, R., Odeberg, J., Hamsten, A., Silveira, A., Hall, P., Nilsson, P., Pawitan, Y., Hägg, S., Uhlen, M., Pedersen, N. L., Magnusson, P. K. E., Schwenk, J. M.
10.1101/464909 — Posted: 2018-11-09 — Discussion: 2020-10-06  EMBO Press
Diflunisal targets the HMGB1/CXCL12 heterocomplex and blocks immune cell recruitment
De Leo, F., Quilici, G., Tirone, M., Mannella, V., De Marchis, F., Preti, A., Gori, A., Casalgrandi, M., Mezzapelle, R., Bianchi, M., Musco, G.
10.1101/563890 — Posted: 2019-03-01 — Discussion: 2020-10-06  EMBO Press
Disrupting HIV-1 capsid formation causes cGAS sensing of viral DNA
Sumner, R. P., Harrison, L., Touizer, E., Peacock, T. P., Spencer, M., Zuliani-Alvarez, L., Towers, G. J.
10.1101/838011 — Posted: 2019-11-11 — Discussion: 2020-10-06  EMBO Press
Programmable and portable CRISPR-Cas transcriptional activation in bacteria
Ho, H.-I., Fang, J. R., Cheung, J., Wang, H. H.
10.1101/2020.01.03.882431 — Posted: 2020-01-03 — Discussion: 2020-10-06  EMBO Press
Protective anti-prion antibodies in human immunoglobulin repertoires
Senatore, A., Frontzek, K., Emmenegger, M., Chincisan, A., Losa, M., Reimann, R., Horny, G., Guo, J., Fels, S., Sorce, S., Zhu, C., George, N., Ewert, S., Pietzonka, T., Hornemann, S., Aguzzi, A.
10.1101/2020.02.05.933721 — Posted: 2020-02-05 — Discussion: 2020-10-06  EMBO Press
PI 3-kinase delta enhances axonal PIP3 to support axon regeneration in the adult CNS
Barber, A. C., Evans, R. S., Nieuwenhuis, B., Pearson, C. S., Fuchs, J., MacQueen, A. R., Erp, S. v., Haenzi, B., Hulshof, L. A., Osborne, A., Conceicao, R., Deshpande, S. S., Cave, J., ffrench-Constant, C., Smith, P. D., Okkenhaug, K., Eickholt, B. J., Martin, K. R., Fawcett, J. W., Eva, R.
10.1101/787994 — Posted: 2019-09-30 — Discussion: 2020-10-06  EMBO Press
Molecular mechanism of attenuation of heat shock transcription factor 1 activity
Kmiecik, S. W., Le Breton, L., Mayer, M. P.
10.1101/803361 — Posted: 2019-10-15 — Discussion: 2020-10-06  EMBO Press

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