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475 Reviews — All Partners — Genomics

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Identification of protein-protected mRNA fragments and structured excised intron RNAs in human plasma by TGIRT-seq peak calling
Yao, J., Wu, D. C., Nottingham, R. M., Lambowitz, A. M.
10.1101/2020.06.25.171439 — Posted: 2020-06-27 — Discussion: 2020-09-15  eLife
Large-scale analysis of DNA methylation identifies cellular alterations in blood from psychosis patients and molecular biomarkers of treatment-resistant schizophrenia.
Hannon, E., Dempster, E., Mansell, G., Burrage, J., Bass, N., Bohlken, M., Corvin, A., Curtis, C., Dempster, D., Di Forta, M., Dinan, T., Donohoe, G., Gaughran, F., Gill, M., Gillespie, A., Gunasinghe, C., Hulshoff, H., Hultman, C., Johansson, V., Kahn, R., Kaprio, J., Kenis, G., Kowalec, K., MacCabe, J., McDonald, C., McQuillin, A., Morris, D., Murphy, K., Mustard, C., Nenadic, I., O'Donovan, M., Quattrone, D., Richards, A., Rutten, B., St. Clair, D., Therman, S., Toulopoulou, T., Van Os, J., Waddington, J., Wellcome Trust Case Control Consortium 2, , CRESTAR Consortium, , Sullivan, P., Bre
10.1101/2020.04.05.026211 — Posted: 2020-04-05 — Discussion: 2020-09-04  eLife
Massively multiplex single-molecule oligonucleosome footprinting
Abdulhay, N. J., McNally, C. P., Hsieh, L. J., Kasinathan, S., Keith, A., Estes, L. S., Karimzadeh, M., Underwood, J. G., Goodarzi, H., Narlikar, G. J., Ramani, V.
10.1101/2020.05.20.105379 — Posted: 2020-05-22 — Discussion: 2020-08-03  eLife
Increased processing of SINE B2 non coding RNAs unveils a novel type of transcriptome de-regulation underlying amyloid beta neuro-pathology
Cheng, Y., Saville, L., Gollen, B., Isaac, C., Mehla, J., Mohajerani, M., Zovoilis, A.
10.1101/2020.07.20.212886 — Posted: 2020-07-21 — Discussion: 2020-07-23  Review Commons
An unexpected contribution of lincRNA splicing to enhancer function.
Tan, J. Y., Biasini, A., Young, R. S., Marques, A.
10.1101/287706 — Posted: 2018-03-23 — Discussion: 2020-07-15  EMBO Press
Status-dependent aging rates in long-lived, social mole-rats are shaped by HPA stress axis
Sahm, A., Hoffmann, S., Koch, P., Henning, Y., Bens, M., Groth, M., Burda, H., Begall, S., Ting, S., Goetz, M., Van Daele, P., Staniszewska, M., Klose, J., Costa, P. F., Platzer, M., Szafranski, K., Dammann, P.
10.1101/2020.02.22.961011 — Posted: 2020-02-23 — Discussion: 2020-07-06  eLife
The activity of human enhancers is modulated by the splicing of their associated lncRNAs.
Tan, J. Y., Marques, A. C.
10.1101/2020.04.17.045971 — Posted: 2020-04-17 — Discussion: 2020-06-17  Review Commons
Start codon disruption with CRISPR/Cas9 prevents murine Fuchs' endothelial corneal dystrophy
Uehara, H., Zhang, X., Pereira, F., Narendran, S., Choi, S., Bhuvanagiri, S., Liu, J., Ravi Kumar, S., Bohner, A., Carroll, L., Archer, B., Zhang, Y., Liu, W., Gao, G., Ambati, J., Jun, A. S., Ambati, B. K.
10.1101/2020.03.18.996728 — Posted: 2020-03-20 — Discussion: 2020-06-16  eLife
SARS-CoV-2 receptor ACE2 and TMPRSS2 are predominantly expressed in a transient secretory cell type in subsegmental bronchial branches
Lukassen, S., Chua, R. L., Trefzer, T., Kahn, N. C., Schneider, M. A., Muley, T., Winter, H., Meister, M., Veith, C., Boots, A. W., Hennig, B. P., Kreuter, M., Conrad, C., Eils, R.
10.1101/2020.03.13.991455 — Posted: 2020-03-14 — Discussion: 2020-06-04  EMBO Press
Local rewiring of genome - nuclear lamina interactions by transcription.
Brueckner, L., Zhao, P. A., van Schaik, T., Leemans, C., Sima, J., Peric-Hupkes, D., Gilbert, D. M., van Steensel, B.
10.1101/685255 — Posted: 2019-06-27 — Discussion: 2020-06-04  EMBO Press

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