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Centrosome Migration and Apical Membrane Formation in Polarized Epithelial Cells: Insights from the MDCK Cyst Model
Wang, P.-K., Lin, K.-h., Tang, T. K.
10.1101/2024.06.17.598507 — Posted: 2024-06-20 — Discussion: 2025-12-31  eLife
Shifting the PPARγ conformational ensemble towards a transcriptionally repressive state improves covalent inhibitor efficacy
Arifova, L., MacTavish, B. S., Laughlin, Z., Karadi Girdhar, M. N., Shang, J., Li, M.-H., Yu, X., Zhu, D., Kamenecka, T. M., Kojetin, D.
10.1101/2025.03.04.640448 — Posted: 2025-03-05 — Discussion: 2025-12-31  eLife
Efficiency and localisation of AURKA degradation by PROTACs is modulated by deubiquitinases UCHL5 and target-selective OTUD6A
Cardno, A., Roberts, K., Lindon, C.
10.1101/2025.04.23.650020 — Posted: 2025-04-23 — Discussion: 2025-12-31  eLife
PH sensitivity of cerebrospinal fluid-contacting neurons involves the modulation of phasic and tonic currents mediated by PKD2L1 channels located in the apical process.
Vitar, M., Prieto, D., Malas, S., Russo, R. E., Trigo, F. F.
10.1101/2025.08.24.671961 — Posted: 2025-08-27 — Discussion: 2025-12-31  eLife
The livebearers platyfish and swordtails partially regenerate their hearts with persistent scarring
Hisler, V., Rees, L., Blanchoud, S., Lischer, H. E. L., Bruggmann, R., Jazwinska, A.
10.1101/2025.09.23.678041 — Posted: 2025-09-25 — Discussion: 2025-12-31  eLife
Fragile nucleosomes are essential for RNA Polymerase II to transcribe in eukaryotes
Li, L., Hunter, S., Leach, S., Zhuang, Y., Liu, H., Gao, J., Zhang, Q., Stasevich, T. J., Kimura, H., Dowell, R. D., Zhang, G.
10.1101/2025.10.08.681188 — Posted: 2025-10-11 — Discussion: 2025-12-31  eLife
SMC complex unidirectionally translocates DNA by coupling segment capture with an asymmetric kleisin path
Yamauchi, M., Brandani, G. B., Terakawa, T., Takada, S.
10.1101/2024.04.29.591782 — Posted: 2024-05-02 — Discussion: 2025-12-30  eLife
The Drosophila EGF domain protein Uninflatable sets the switch between wrapping glia growth and axon wrapping instructed by Notch
Baldenius, M., Kautzmann, S., Kottmeier, R., Klämbt, C.
10.1101/2025.01.02.631076 — Posted: 2025-01-02 — Discussion: 2025-12-30  eLife
Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels.
Weir, K., Lyu, P., Kandoi, S., An, R., Pannullo, N., Palaxxo, I., Tangeman, J., Shi, J., DeVries, S., Merriman, D., Qian, J., Blackshaw, S.
10.1101/2025.04.25.650540 — Posted: 2025-04-29 — Discussion: 2025-12-30  eLife
Targeted Computational Design of an Interleukin-7 Superkine with Enhanced Folding Efficiency and Immunotherapeutic Efficacy
Lim, S.-K., Lin, W.-C., Pan, Y.-C., Huang, S.-W., Yu, Y.-A., Chang, C.-H., Hu, C.-M. J., Mou, C.-Y., Mou, K. Y.
10.1101/2025.06.03.657627 — Posted: 2025-06-06 — Discussion: 2025-12-30  eLife

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