Channel:  Aligning Science Across Parkinson's (ASAP)

449 Articles

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CREsted: modeling genomic and synthetic cell type-specific enhancers across tissues and species
Kempynck, N., De Winter, S., Blaauw, C. H., Konstantakos, V., Dieltiens, S., Eksi, E. C., Bercier, V., Taskiran, I. I., Hulselmans, G., Spanier, K., Christiaens, V., Van Den Bosch, L., Mahieu, L., Aerts, S.
10.1101/2025.04.02.646812 — Posted: 2025-04-03
iNeurons are sweet, maybe too sweet? Exploring the impact of media composition on PINK1-dependent mitophagy
O'Callaghan, B., Melandri, D., Soltic, D., Cosker, K., Soutar, M. P. M., Plun-Favreau, H.
10.1101/2025.04.01.646648 — Posted: 2025-04-03
Baseline α-synuclein seeding activity and disease progression in sporadic and genetic Parkinson's disease in the PPMI cohort
Schumacher, J. G., Zhang, X., Macklin, E. A., Wang, J., Bayati, A., Dijkstra, J. M., Watanabe, H., Schwarzschild, M. A., Cortese, M., Zhang, X., Chen, X.
10.1101/2024.09.27.24311107 — Posted: 2025-04-02
In situ cryo-ET visualization of mitochondrial depolarization and mitophagic engulfment
Rose, K., Herrmann, E., Kakudji, E. V., Lizarrondo, J., Celebi, A. Y., Wilfling, F., Lewis, S. C., Hurley, J. H.
10.1101/2025.03.24.645001 — Posted: 2025-03-25
Soluble Immune Factor Profiles in Blood and CSF Associated with LRRK2 Mutations and Parkinson's Disease
Jaffery, R., Zhao, Y., Ahmed, S., Schumacher, J. G., Ahn, J., Shi, L., Wang, Y., Tan, Y., Chen, K., Tawbi, H., Wang, J., Schwarzschild, M. A., Peng, W., Chen, X.
10.1101/2025.03.20.644460 — Posted: 2025-03-24
Validation of a Mitochondrial Polygenic Score for Parkinson's Disease
Ooi, J. C. E., Tay, Y. W., Tan, A. H., Lin, C.-H., Brolin, K. A., Laabs, B.-H., Sendel, S., König, I. R., Caliebe, A., Gabbert, C., Andersh, K. M., Jones, L., Lange, L. M., Fiske, B., Sue, C., Klein, C., Trinh, J., Lüth, T., Global Parkinson's Genetics Program (GP2)
10.1101/2025.03.18.25323898 — Posted: 2025-03-19
PPM1M, a LRRK2-counteracting, phosphoRab12-preferring phosphatase with potential link to Parkinsons disease
Chiang, C. Y., Pratuseviciute, N., Lin, Y.-E., Adhikari, A., Yeshaw, W. M., Flitton, C., Sherpa, P. L., Tonelli, F., Rektorova, I., Lynch, T., Siuda, J., Rudzinska-Bar, M., Pulyk, O., Bauer, P., Beetz, C., Dickson, D. W., Ross, O. A., Wszolek, Z., Klein, C., Zimprich, A., Alessi, D. R., Sammler, E. M., Pfeffer, S. R.
10.1101/2025.03.19.644182 — Posted: 2025-03-19
Novel Parkinson's Disease Genetic Risk Factors Within and Across European Populations
The Global Parkinson's Genetics Program (GP2), , Leonard, H. L.
10.1101/2025.03.14.24319455 — Posted: 2025-03-17
17q21.31 locus regulates Parkinson's disease relevant pathways through KANSL1 activity
Hicks, A. R., O'Callaghan, B., Brenton, J. W., Grant-Peters, M., Fairbrother-Browne, A., Rocamora Perez, G., Loh, C. A., Reynolds, R. H., Gustavsson, E. K., Montgomery, K., Tsalenchuk, M., Real, R., Morris, H., Lunnon, K., Marzi, S. J., Jaunmuktane, Z., Hardy, J., Plun-Favreau, H., Ryten, M.
10.1101/2025.03.17.641409 — Posted: 2025-03-17
Molecular and cellular signatures differentiate Parkinson's disease from Parkinson's disease with dementia
Fairbrother-Browne, A., Grant-Peters, M., Brenton, J. W., Nelvagal, H., Reynolds, R. H., Lim, Y. M., Gustavsson, E. K., Macpherson, H., Montgomery, K., Evans, J. R., Hicks, A. R., Chiraki, N., Curless, T., Real, R., Xenakis, T., Houlden, H., Morris, H. R., Gandhi, S., Wood, N. W., Hardy, J., Jaunmuktane, Z., Ryten, M.
10.1101/2025.03.04.641379 — Posted: 2025-03-11

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