Channel:  Francis Crick Institute

1,190 Articles

Cancer-driven neutrophil priming couples systemic epithelial regenerative programs with pre-metastatic niche formation
Rabas, N., Bridgeman, V., Hennequart, M., Rodrigues, F. S., Farias, A., Ferreira, R. M. M., Axarlis, K., Nduka, O., Chakravarty, P., Legrave, N., Furlani, I., MacRae, J., Malanchi, I.
10.1101/2025.10.20.683483 — Posted: 2025-10-31
Near real-time data on the human neutralizing antibody landscape to influenza virus to inform vaccine-strain selection in September 2025
Kikawa, C., Huddleston, J., Loes, A. N., Turner, S. A., Lee, J., Barr, I. G., Cowling, B. J., Englund, J. A., Greninger, A. L., Harvey, R., Hasegawa, H., Ho, F., Lacombe, K., Leung, N. H., Lewis, N. S., Peck, H., Watanabe, S., Smith, D. J., Bedford, T., Bloom, J. D.
10.1101/2025.09.06.674661 — Posted: 2025-10-28
Inhibition of neutrophil degranulation by Nexinhib20 delays the development of radiation-induced pulmonary fibrosis
Ruhland, S., Nikolatou, K., Bridgeman, V. L., Rizou, T., Sahai, E., Bordoloi, J., Nolan, E., Elosegui-Artola, A., Malanchi, I.
10.1101/2025.10.22.684057 — Posted: 2025-10-23
Autoantibody origins in lupus and in relapse post CAR-T therapy
Grenov, A., Yoon, J., Snell, D. M., Mikolajczak, A., Wang, H., Gurel, E., Rodriguez-Ronchel, A., Yegen, G., Lee, L., Artim Esen, B., Rahman, A., Maciocia, P., Vinuesa, C.
10.1101/2025.10.20.683393 — Posted: 2025-10-20
Genome-wide Chromosome-specific Aneuploidy Engineering and Phenotypic Characterization with CRISPR-Taiji
Feng, H., Deng, D., Dahiya, R., Wang, L., Zeng, J., Tan, B. J. Y., Byrne, F., Shepherd, S. T. C., Wang, J., Johnson, S. C., Harrod, A., Lane, K. A., Fendler, A., Cattin, A.-L., Tippu, Z., Nie, M., Zhao, Y., Wang, R., Ai, W., Bouricha, O., Barber, T., Dovga, Y., Xu, Y., Shen, W., Sun, Z., Wang, H., Zhu, J., Xu, Y., Devito, L. G., Healy, L., Lim, E. S., OToole, S. M., Akker, S., Drake, W. M., Jin, H., Downs, J. A., McClelland, S. E., Diffley, J. F. C., Ly, P., Turajlic, S.
10.1101/2025.04.25.650684 — Posted: 2025-10-18
VGLL1 contributes to both the transcriptome and epigenome of the developing trophoblast compartment
Calderon, R. I., Sah, N., Huang, M., Kallol, S., Kittle, R. H., Shaik, W., Abdelaal, A., Chousal, J. N., Morey, R., Bui, T., Mitre, A., Fogarty, N. M. E., Gerri, C., Manalo, Z., Zheng, C., DeHoff, P. M., Home, P., Niakan, K., Cook-Andersen, H., Fisch, K. M., Paul, S., Soncin, F.
10.1101/2025.04.25.650693 — Posted: 2025-10-15
The origin and molecular evolution of the mammalian liver cell architecture
Yuan, X., Rodriguez-Montes, L., Zaremba, B., Trost, N., Schneider, C., Schmidt, J., Berki, B., Ibberson, D., Leushkin, E., Nickel, B., Palkovits, M., Truman, R. W., Barsh, G., Lees, J., Fallahshahroudi, A., Grützner, F., Tzika, A. C., Milinkovitch, M. C., Pääbo, S., Cardoso-Moreira, M., Kaessmann, H.
10.1101/2025.10.14.682049 — Posted: 2025-10-14
Extensive and differential platinum chemotherapy mutagenesis in children
Wenger, A., Lee-Six, H., Dave, M., Layeghifard, M., Lawson, A. R. J., Abascal, F., Nicola, P. A., Treger, T. D., Ogbonnah, T., Parks, C., Oliver, T. R. W., Kennedy, J., Hodder, A., Anderson, N. D., Silva, F. L. T., Trinh, M. K., Dowe, T., Habarwaa, M., Sun, J. J., Assia-Zamora, S., Cortes-Cerisuelo, M., Jassem, W., Town, C., Dhawan, A., Jain, V., Straathof, K., Deheragoda, M., Martincorena, I., Palm, L., Hutchinson, J. C., Coorens, T. H. H., Trayers, C., Heaton, N., Shlien, A., Zen, Y., Rouhani, F. J., Behjati, S.
10.1101/2025.10.12.681852 — Posted: 2025-10-14
The SNCA A53T mutation sensitizes human neurons and microglia to ferroptosis
Mahoney-Sanchez, L., Clarke-Lucas, H., Penverne, A., Evans, J. R., D'Sa, K., Strohbuecker, S., Lopex Garcia, P., Cosker, K., Soltic, D., O'Callaghan, B. J., Griffiths, A., Pintchovski, S. A., Plun-Favreau, H., Hallqvist, J., Mills, K., Gandhi, S.
10.1101/2025.10.13.682089 — Posted: 2025-10-14
Ecological cues orchestrate concerted courtship in a Drosophila host specialist
Brand, P., Keller, K., Coleman, R. T., Eghbali, N. B., Zylka, S., Prieto-Godino, L. L., Ruta, V.
10.1101/2025.10.13.681913 — Posted: 2025-10-14

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