Channel:  Francis Crick Institute

1,171 Articles

Chaperone AIP Couples mTORC1 Activation and Catabolic Metabolism During Neonatal Development
Korbonits, M., Wang, X., Barry, S., Lim, C. T., Suleyman, O., De Tito, S., Uddin, N. B., Vignola, M. L., Hall, C., Perna, L., Chapple, P., Henson, S., Morales, V., Bianchi, K., Edvardsson, V. O., Ragnarsson, K. A., Kristinsdottir, V. E., Debeer, A., Sleyp, Y., Zinchenko, R. A., Anderson, G., Duchen, M., Singh, K., Chung, C.-Y., Yuan, Y., Patel, S., Aksoy, E., Borovikov, A., Bjornsson, H. T., Van Esch, H., Czibik, G., Tooze, S., Brennan, C. H., Haworth, O.
10.1101/2025.09.18.677011 — Posted: 2025-09-18
Conserved Aberrant Developmental Trajectories of Human and Mouse SBMA Motor Neurons
Devine, H., Roberts, M. J., Ziff, O. J., Hanna, M. G., Greensmith, L., Patani, R., Malik, B.
10.1101/2025.09.17.674754 — Posted: 2025-09-17
Mechanisms for cross-neutralisation of diverse bat sarbecoviruses
Upadhyay, A., Seow, J., Alguel, Y., Newman, J., Thakur, N., Hay, A., Tam, J. C. H., Nans, A., Orton, R., Bailey, D., Cherepanov, P., Doores, K. J.
10.1101/2025.09.17.674891 — Posted: 2025-09-17
Characterisation of LAMP1- and LAMP2A-positive organelles in neurons
Abouward, R., Abdelhafid, A. M., Wilkins, O. G., Lee, S.-Y., Ibrahim, F., Skehel, M., Ting, A., Birsa, N., Ule, J., Schiavo, G.
10.1101/2025.09.17.676809 — Posted: 2025-09-17
Morphogen and juxtacrine signalling dynamically integrate to specify cell fates with single-cell resolution
Donoghue, A., Mosby, L., Lago-Baldaia, I., Hodgetts, T., Ursu, E., Erten, Z., Hadjivasiliou, Z., Fernandes, V. M.
10.1101/2025.09.15.676088 — Posted: 2025-09-17
Cell migration sculpts evolutionary dynamics favouring therapy resistance in lung cancer
Bhargava, A., Fu, X., Bailey, S., Naito, Y., Mohammadi, H., Hynds, R. E., Hooper, S., Biswas, D., Le Marois, A., Kumar, S., Alexandrov, Y., French, P. M., McGinty, J., Bates, P. A., Swanton, C., Sahai, E.
10.1101/2025.09.15.675999 — Posted: 2025-09-16
Streptococcus pneumoniae accessory capsular genes modulate fitness, pathogenicity and immune evasion
Chan, J. M., Flynn, H. R., Kim, S., Demetriou, H., Ramos-Sevillano, E., Alsari, A., Roalfe, L., Ercoli, G., Kalizang'oma, A., Brown, C., Chaguza, C., French, N., Brown, J. S., Goldblatt, D., de Carvalho, L. P. S., Heyderman, R.
10.1101/2025.09.11.675585 — Posted: 2025-09-15
Investigations into fission yeast chromosome size determinants
Wu, P.-S., Fallesen, T., Uhlmann, F.
10.1101/2025.09.15.676266 — Posted: 2025-09-15
Immunogenicity and Efficacy of Digitally Immune Optimised H1N1 Vaccine Candidates in Swine and Murine Animal Models
Del Rosario, J. M. M., van Diemen, P. M., Frost, S., vishwanath, s., Sujit, S. B., Ashokan, S. K., Mollett, B. C., Ramsay, A. M., Simpson, B., Asbach, B., Carnell, G. W., Chan, A., Tonks, P., Temperton, N. J., Davies, M., McCauley, J. W., Kinsley, R., Wagner, R., Everett, H. E., Heeney, J. L.
10.1101/2025.09.12.675937 — Posted: 2025-09-14
SLFN11 restricts escape from telomere crisis to prevent alternative lengthening of telomeres
Segura-Bayona, S., Borel, V., Stanage, T. H., Maric, M., Walter, M., Oliveira, R. A., Li, S., Idilli, A. I., Peritore, M., Hewitt, G., Hekkelman, M., Snell, D. M., Jones, S. T., Cheshire, C., Elezi, A., Chakravarty, P., Mitter, R., Mikolajczak, A., Gee, H. E., Nye, E., O'Sullivan, R. J., Singhi, A. D., Brummelkamp, T. R., Cesare, A. J., Boulton, S. J.
10.1101/2025.09.10.675313 — Posted: 2025-09-10

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