Channel:  Aligning Science Across Parkinson's (ASAP)

512 Articles

Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability
Vatsa, N., Brynildsen, J. K., Goralski, T. M., Kurgat, K., Meyerdirk, L., Breton, L., DeWeerd, D., Brasseur, L., Turner, L., Becker, K., Gallik, K. L., Isaguirre, C., Sheldon, R. D., Bassett, D. S., Henderson, M. X.
10.1101/2024.10.22.619411 — Posted: 2026-06-12
Striatal ensembles specify and control ongoing actions at fine motorresolution
Rodrigues-Vaz, I., Athalye, V. R., Rodrigues, H. F. M., Peterka, D. S., Costa, R. M.
10.64898/2025.12.03.692128 — Posted: 2026-06-12
Structural Mechanism and Cellular Restriction of Tau Seeding from Endolysosomes
Herrmann, E., Tan, S., Rose, K. M., Hooy, R. M., Hurley, J. H.
10.64898/2026.06.08.731026 — Posted: 2026-06-10
A genome-wide association study of young onset Parkinson's disease in European ancestry
Lie, I. H., van Wetering, J., Valori, M., Brolin, K. A., Step, K., Schulte, C., Iwaki, H., Bandres-Ciga, S., Leonard, H. L., Sharma, M., International Parkinson's Disease Genomics Consortium, , Global Parkinson's Genetics Program, , Singleton, A., Pihlstrom, L.
10.64898/2026.06.03.26354799 — Posted: 2026-06-04
Structural basis for regulation of the proteasome 20S core particle by the Parkinsonism-associated proteins FBXO7 and PI31
Adolf, F., Goodall, E. A., Singh, E., von Gronau, S., Fermin Perez, E., Fung, D., Mueller, B. S., Paulo, J. A., Hanna, J., Harper, J. W., Schulman, B. A.
10.64898/2026.05.28.728263 — Posted: 2026-06-04
Spermidine suppresses glial inflammation and parkinsonian abnormalities in ATP13A2 deficiency
Cascalho, A., Sati, A., Dhondt, H., Schoonvliet, N., Kaempf, N., Coccia, E., Mamalaki, A., Behrens, M. I., Brüggemann, N., Glatzel, M., Baekelandt, V., Klein, C., Eggermont, J., Verstreken, P., Blanchard, J., Vangheluwe, P.
10.64898/2026.05.23.26353575 — Posted: 2026-06-04
Emergence of Task-Related Motor Cortical Dysfunction in Mice with Progressive Parkinsonism
Chehade, H. D., Berezhnoi, D., Somavarapu, S., Wang, Z., Jiang, J., Chen, L., Risk, B. B., Wichmann, T., Chu, H.-Y.
10.64898/2026.05.29.728524 — Posted: 2026-06-02
Genetic screening and metabolomics identify glial adenosine metabolism as a therapeutic target in Parkinson's disease
Sodders, M. J., Avila-Pacheco, J., Okorie, E. C., Tahmasebidehkordi, H., Marathi, A., Kumari, N., Lakhani, M., Schiro, A., Shen, M., Sriram, N., Bullock, K., Pierce, K., Dennis, C., Jeanfavre, S., Sarkar, S., Weykopf, B., Muratore, C., Young-Pearse, T. L., Mazzulli, J., Scherzer, C. R., Clish, C., Olsen, A. L.
10.1101/2024.05.15.594309 — Posted: 2026-06-01
AAV tools enable functional modulation and readout of central and peripheral nervous systems in spiny mice
Chung, J. H., Donahue, R. R., Griffiths, J. A., Fan, Y., Lin, C., Chen, X., Dutta, S., Mazmanian, S., Seifert, A. W., Gradinaru, V.
10.64898/2026.05.08.723863 — Posted: 2026-05-29
In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association
Basiashvili, T., Hutchings, J., Chen, S., Karasmanis, E. P., Flaherty, W. A., Leschziner, A. E., Villa, E.
10.64898/2025.12.18.694444 — Posted: 2026-05-28

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