Channel:  Aligning Science Across Parkinson's (ASAP)

419 Articles

Elevated brain α-synuclein, phosphorylated-tau, and oxidative stress in mice that survived influenza A pneumonitis
Lunn, M. O., Lengacher, N. A., Hake-Volling, Q., Tomlinson, J. J., aSCENT-PD Investigators, , Brown, E. G., Schlossmacher, M. G.
10.1101/2025.07.31.667659 — Posted: 2025-08-01
LRRK2-mutant microglia and neuromelanin synergize to drive dopaminergic neurodegeneration in an iPSC-based Parkinson's disease model
Blasco-Agell, L., Espinal, M. P., Testa, V., Roch, G., Montero-Mu, J., Fern, I., Baruffi, V., Gonzalez-Sepulveda, M., Richaud-Patin, Y., Jim, S., Cuadros, T., Cladera-Sastre, J. M., Compte, J., Manglano-Artu"n"edo, Z., Ventura, S., Otero, M. J., Tolosa, E., Raya, A., Vila, M., Consiglio, A.
10.1101/2024.10.07.616997 — Posted: 2025-07-30
CNV-Finder: Streamlining Copy Number Variation Discovery
Kuznetsov, N., Daida, K., Makarious, M. B., Al-Mubarak, B., Atterling Brolin, K., Malik, L., Kouam, C., Baker, B., Real, R., Step, K., Lange, L. M., Wu, L., Ostrozovicova, M., Andersh, K. M., Kung, P.-J., Mecheri, Y., Tay, Y.-W., Soundous Malek, B., Al Tassan, N., Teresa Perinan, M., Hong, S., Koretsky, M. J., Sargeant, L., Levine, K., Blauwendraat, C., Billingsley, K. J., Bandres-Ciga, S., Leonard, H. L., Bardien, S., Morris, H. R., Singleton, A. B., Nalls, M. A., Vitale, D., The Global Parkinson's Genetics Program
10.1101/2024.11.22.624040 — Posted: 2025-07-26
AutoMorphoTrack: An Automated Python Package for Organelle Morphology, Motility, and Colocalization Analysis in Live-Cell Imaging
Bayati, A., Schumacher, J. G., Chen, X.
10.1101/2025.07.19.665650 — Posted: 2025-07-25
Sex-stratified analysis of the potential association between PGLYRP2 rs892145 variant and Parkinson's disease across diverse ancestral populations
Avila, C. L., Chaparro Solano, H. M., Quintana-Pena, V., Aberg, K., the Global Parkinson's Genetics Program (GP2), , Atterling Brolin, K.
10.1101/2025.07.23.25331993 — Posted: 2025-07-24
DIO-SPOTlight Transgenic Mouse to Functionally Monitor Protein Synthesis Regulated by the Integrated Stress Response
Oliver, M. L., Caffall, Z. F., Eatman, C. B., Faw, T. D., Calakos, N.
10.1101/2024.10.14.618312 — Posted: 2025-07-23
Enhanced beta power emerges from simulated parkinsonian primary motorcortex
Doherty, D. W., Chen, L., Smith, Y., Wichmann, T., Chu, H.-Y., Lytton, W. W.
10.1101/2024.05.23.595566 — Posted: 2025-07-20
Genotype-phenotype association study conducted on LARGE-PD reveals novel loci associated with Parkinson's Disease.
Leal, T. P., Waldo, E., Duarte-Zambrano, F., Inca-Martinez, M., Ramchandra, J., Chaparro-Solano, H. M., Anello, A. E., Borda, V., Gouveia, M. H., Teixeira-dos-Santos, D., Reyes-Perez, P., Gatto, E. M., Santos-Lobato, B. L., Eufraseo, G., Letro, G. H., Arboleda, G., Bernal-Pacheco, O., Orozco, J., Munoz, B., Chana-Cuevas, P., Aguillon, D., Moreno, S., Torrealba-Acosta, G., Lobo-Prada, T., Muller, V., Lopez Razquin, C. M., Braga-Neto, P., Duron, R., Rodriguez-Violante, M., Hernandez-Medrano, A. J., Cervantes-Arriaga, A., Martinez-Ramirez, D., Schuh, A. F. S., de Mello Rieder, C. R., Cornejo-Oliv
10.1101/2025.07.18.25331793 — Posted: 2025-07-18
Mapping the causal chain from genetic risk variants to lipid dysmetabolism in Parkinsons disease
DePaula, R., Kim, J., Rhinn, H., Saade, H., Chavez, F., Segura, T., Lozano, M. V., Etoundi, M., Silos, K., Korchina, V., doddapaneni, h. v., Venner, E., Masdeu, J. C., Pavlik, V., Yu, M. M., Lin, C.-Y. R., Jankovic, J., Buchman, A. S., Muzny, D. M., Gibbs, R. A., Elsea, S. H., Abeliovich, A., Lansbury, P., Vanegas-Arroyave, N., Shaw, C. A., Shulman, J. M.
10.1101/2025.07.14.25331535 — Posted: 2025-07-15
Cryo-electron tomography reveals the microtubule-bound form of inactive LRRK2
Chen, S., Basiashvili, T., Hutchings, J., Murillo, M. S., Suarez, A. V., Xiong, E., Louro, J. A., Leschziner, A. E., Villa, E.
10.1101/2024.06.18.599606 — Posted: 2025-07-10

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