Channel:  Aligning Science Across Parkinson's (ASAP)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

335 Articles

Natural phasic inhibition of dopamine neurons signals cognitive rigidity
Burwell, S. C. V., Yan, H., Lim, S. S. X., Shields, B. C., TADROSS, M. R.
10.1101/2024.05.09.593320 — Posted: 2024-07-13
Loss of the lysosomal lipid flippase ATP10B leads to progressive dopaminergic neurodegeneration and Parkinsonian motor deficits
Sanchiz-Calvo, M., Coccia, E., Cawthorne, C., Parfitt, G., Van Laere, K., Torre-Muruzabal, T., Cabezudo, D., Tsafaras, G., Cascalho, A., Van Den Haute, C., Vangheluwe, P., Blanchard, J., Bentea, E., Baekelandt, V.
10.1101/2024.07.09.602700 — Posted: 2024-07-13
SynBot: An open-source image analysis software for automated quantification of synapses
Savage, J. T., Ramirez, J., Risher, W. C., Wang, Y., Irala, D., Eroglu, C.
10.1101/2023.06.26.546578 — Posted: 2024-07-12
The Pgb1 locus controls glycogen aggregation in astrocytes of the aged hippocampus without impacting cognitive function
Gomez-Pascual, A., Glikman, D. M., Ng, H. X., Tomkins, J. E., Lu, L., Xu, Y., Ashbrook, D. G., Kaczorowski, C., Kempermann, G., Killmar, J., Mozhui, K., Ohlenschlaeger, O., Aebersold, R., Ingram, D. K., Williams, E. G., Williams, R. W., Overall, R. W., Jucker, M., de Bakker, D. E. M.
10.1101/2023.11.22.567373 — Posted: 2024-07-08
Global Perspectives on Returning Genetic Research Results in Parkinson's Disease
Tan, A. H., Saffie-Awad, P., Schuh, A. F. S., Lim, S.-Y., Madoev, H., Ahmad-Annuar, A., Solle, J., Wegel, C. E., Doquenia, M. L., Dey, S., Perinan, M. T., Makarious, M. B., Fiske, B., Morris, H. R., Noyce, A. J., Kumar, K. R., Klein, C.
10.1101/2024.07.06.24309029 — Posted: 2024-07-07
The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4
Feringa, F. M., Koppes-den Hertog, S. J., Wang, L., Derks, R. J. E., Kruijff, I., Erlebach, L., Heijneman, J., Miramontes, R., Pömpner, N., Blomberg, N., Olivier-Jimenez, D., Johanson, L. E., Cammack, A. J., Giblin, A., Toomey, C. E., Rose, I. V. L., Yuan, H., Ward, M. E., Isaacs, A., Kampmann, M., Kronenberg-Versteeg, D., Lashley, T., Thompson, L. M., Ori, A., Mohammed, Y., Giera, M., van der Kant, R. H. N.
10.1101/2024.07.01.601474 — Posted: 2024-07-03
Genetically Encoded and Modular SubCellular Organelle Probes (GEM-SCOPe) reveal lysosomal and mitochondrial dysfunction driven by PRKN knockout
Goldman, C., Kareva, T., Sarrafha, L., Sahasrabudhe, A., Schuldt, B. R., Ahfeldt, T., Blanchard, J. W.
10.1101/2024.05.21.594886 — Posted: 2024-06-29
Functional efficacy of the MAO-B inhibitor safinamide in murine substantia nigra pars compacta dopaminergic neurons in vitro: a comparative study with tranylcypromine
Zarrilli, B., Giacomet, C., Cossa, F., Federici, M., Berretta, N., Mercuri, N. B.
10.1101/2024.05.28.596142 — Posted: 2024-06-26
Pathogenic LRRK2 mutations cause loss of primary cilia and Neurturin in striatal Parvalbumin interneurons
Lin, Y.-E., Jaimon, E., Tonelli, F., Pfeffer, S. R.
10.1101/2024.06.17.599289 — Posted: 2024-06-25
Presynaptic GABAA receptors control integration of nicotinic input onto dopaminergic axons in the striatum
Brill-Weil, S. G., Kramer, P. F., Yanez, A., Clever, F. H., Zhang, R., Khaliq, Z. M.
10.1101/2024.06.25.600616 — Posted: 2024-06-25

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