Channel:  Aligning Science Across Parkinson's (ASAP)

541 Articles

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Spermidine suppresses glial inflammation and parkinsonian abnormalities in ATP13A2 deficiency
Cascalho, A., Sati, A., Dhondt, H., Schoonvliet, N., Kaempf, N., Coccia, E., Mamalaki, A., Behrens, M. I., Brüggemann, N., Glatzel, M., Baekelandt, V., Klein, C., Eggermont, J., Verstreken, P., Blanchard, J., Vangheluwe, P.
10.64898/2026.05.23.26353575 — Posted: 2026-06-04
A genome-wide association study of young onset Parkinson's disease in European ancestry
Lie, I. H., van Wetering, J., Valori, M., Brolin, K. A., Step, K., Schulte, C., Iwaki, H., Bandres-Ciga, S., Leonard, H. L., Sharma, M., International Parkinson's Disease Genomics Consortium, , Global Parkinson's Genetics Program, , Singleton, A., Pihlstrom, L.
10.64898/2026.06.03.26354799 — Posted: 2026-06-04
Emergence of Task-Related Motor Cortical Dysfunction in Mice with Progressive Parkinsonism
Chehade, H. D., Berezhnoi, D., Somavarapu, S., Wang, Z., Jiang, J., Chen, L., Risk, B. B., Wichmann, T., Chu, H.-Y.
10.64898/2026.05.29.728524 — Posted: 2026-06-02
AAV tools enable functional modulation and readout of central and peripheral nervous systems in spiny mice
Chung, J. H., Donahue, R. R., Griffiths, J. A., Fan, Y., Lin, C., Chen, X., Dutta, S., Mazmanian, S., Seifert, A. W., Gradinaru, V.
10.64898/2026.05.08.723863 — Posted: 2026-05-29
In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association
Basiashvili, T., Hutchings, J., Chen, S., Karasmanis, E. P., Flaherty, W. A., Leschziner, A. E., Villa, E.
10.64898/2025.12.18.694444 — Posted: 2026-05-28
STING dampens the unfolded protein response to enable the presentation of self-antigens on MHC-I during inflammation.
Fahmy, A. M., Ahmadi, A., Lanoix, J., Cannon, T., Badr Elemeery, m. N., Hernandez Paredes, C., Barrette, B., Bonneil, E., Zhong Xu, Y., Ibrahim, M., Arango-Duque, G., Audemard, E. O., Lemieux, S., Chevet, E., Schurr, E., Pierre, P., Gruenheid, S., Thibault, P., McBride, H. M., Desjardins, M.
10.64898/2026.05.25.727656 — Posted: 2026-05-28
The mitochondrial unfolded protein response in human microglia disrupts neuronal-glial communication and promotes senescence
Perez Jimenez, M. J., Lam, A., Weissleder, C., Bertoli, F., Raji, H., Bosch, M., Nemazanyy, I., Kalb, S., Kehili, M., Hirschberg, I., Brunetti, D., Heckenbach, I., Scheibye-Knudsen, M., Deleidi, M.
10.1101/2024.09.03.610925 — Posted: 2026-05-27
Thalamus orchestrates local acetylcholine-dependent dopamine release in the learning striatum
Miller-Hansen, A. J., Zhu, M., Kovaleski, R. F., Demir, B., Lerner, T. N.
10.64898/2026.05.08.723861 — Posted: 2026-05-23
GPNMB and glycosphingolipid measurements in cerebrospinal fluid and plasma from Parkinson's disease patients
Fernandez-Suarez, M. E., Bush, R. J., Di Biase, E., Te Vruchte, D., Priestman, D., Cortina-Borja, M., Cooper, O., Hardy, J., Hallett, P., Isacson, O., Platt, F. M.
10.64898/2026.04.09.712000 — Posted: 2026-05-18
Elucidating the dysbiotic features of gut microbiome, interaction with the human genome, and utility as a biomarker for treatment of Parkinson disease.
Payami, H., Murchison, C. F., Antonello, G., Wallen, Z. D., Dean, M. N., Verster, A., Long, K. R., Waldron, L. D., Sampson, T. R., Standaert, D. G.
10.64898/2026.05.12.724602 — Posted: 2026-05-15

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