Channel:  Aligning Science Across Parkinson's (ASAP)

392 Articles

Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
Parmasad, J.-L. A., Ricke, K. M., Stykel, M. G., Buchner-Duby, B., Nguyen, B., Bruce, A., Geertsma, H. M., Lian, E., Lengacher, N. A., Callaghan, S. M., Joselin, A., Tomlinson, J. J., Schlossmacher, M. G., Stanford, W. L., Ma, J., Brundin, P., Ryan, S. D., Rousseaux, M. W. C.
10.1101/2022.05.02.490309 — Posted: 2023-07-18
Detecting Full-Length EccDNA with FLED and long-reads sequencing
Li, F., Ming, W., Lu, W., Wang, Y., Li, X., Dong, X., Bai, Y.
10.1101/2023.06.21.545840 — Posted: 2023-06-24
LRRK2 Suppresses Lysosome Degradative Activity in Macrophages and Microglia Through MiT-TFE Transcription Factor Inhibition
Yadavalli, N., Ferguson, S. M.
10.1101/2022.12.17.520834 — Posted: 2023-06-16
LRRK2 regulates the activation of the unfolded protein response and antigen presentation in macrophages during inflammation
Fahmy, A. M., Cannon, T., Paredes, C. H., Ahmadi, A., Xu, Y. Z., Barette, B., Ibrahim, M., Lanoix, J., Arango-Duque, G., Schurr, E., Chevet, E., Thibault, P., Gruenheid, S., McBride, H., Desjardins, M.
10.1101/2023.06.14.545012 — Posted: 2023-06-16
Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice.
Delignat-Lavaud, B., Kano, J., Ducrot, C., Masse, I., Mukherjee, S., Giguere, N., Moquin, L., Levesque, C., Burke, S., Bourque, M.-J., Tchung, A., Rosa-Neto, P., Levesque, D., De Beaumont, L., Trudeau, L.-E.
10.1101/2021.09.15.460511 — Posted: 2023-06-15
Localization of PPM1H phosphatase tunes Parkinsons disease-linked LRRK2 kinase-mediated Rab GTPase phosphorylation and ciliogenesis
Yeshaw, W. M., Adhikari, A., Chiang, C. Y., Dhekne, H. S., Wawro, P. S., Pfeffer, S. R.
10.1101/2023.06.15.545139 — Posted: 2023-06-15
Interaction of an alpha-synuclein epitope with HLA-DRB1*15:01 triggers enteric features in mice reminiscent of prodromal Parkinson's disease
Garretti, F., Monahan, C., Sloan, N., Bergen, J., Shariar, S., Kim, S. W., Sette, A., Cutforth, T., Kanter, E., Sulzer, D., Agalliu, D.
10.1101/2022.02.03.479014 — Posted: 2023-06-12
Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine co-varies with risk factors for Parkinson's
Brimblecombe, K. R., Conor-Robson, N., Bataille, C. J. R., Roberts, B. M., Gracie, C., te Water Naude, R., Karthik, G., Russell, A. J., Wade-Martins, R., Cragg, S. J.
10.1101/2020.07.03.186411 — Posted: 2023-06-09
Genome-wide determinants of mortality and motor progression in Parkinson's disease
Tan, M. M., Lawton, M. A., Pollard, M. I., Brown, E. E., Real, R., Martinez, A., Bekadar, S., Jabbari, E., Reynolds, R. H., Iwaki, H., Blauwendraat, C., Kanavou, S., Hubbard, L., Malek, N., Grosset, K. A., Bajaj, N., Barker, R. A., Burn, D. J., Bresner, C., Foltynie, T., Wood, N. W., Williams-Gray, C. H., Andreassen, O. A., Toft, M., Elbaz, A., Artaud, F., Brice, A., Corvol, J.-C., Aasly, J., Farrer, M. J., Nalls, M. A., Singleton, A. B., Williams, N. M., Ben-Shlomo, Y., Hardy, J., Hu, M. T., Grosset, D. G., Shoai, M., Pihlstrom, L., Morris, H. R.
10.1101/2022.07.07.22277297 — Posted: 2023-06-09
escheR: Unified multi-dimensional visualizations with Gestalt principles
Guo, B., Huuki-Myers, L. A., Grant-Peters, M., Collado-Torres, L., Hicks, S. C.
10.1101/2023.03.18.533302 — Posted: 2023-06-08

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