Channel:  Aligning Science Across Parkinson's (ASAP)

546 Articles

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LRRK2-mutant microglia and neuromelanin synergize to drive dopaminergic neurodegeneration in an iPSC-based Parkinson's disease model
Blasco-Agell, L., Espinal, M. P., Testa, V., Roch, G., Montero-Mu, J., Fern, I., Baruffi, V., Gonzalez-Sepulveda, M., Richaud-Patin, Y., Jim, S., Cuadros, T., Cladera-Sastre, J. M., Compte, J., Manglano-Artu"n"edo, Z., Ventura, S., Otero, M. J., Tolosa, E., Raya, A., Vila, M., Consiglio, A.
10.1101/2024.10.07.616997 — Posted: 2025-07-30
CNV-Finder: Streamlining Copy Number Variation Discovery
Kuznetsov, N., Daida, K., Makarious, M. B., Al-Mubarak, B., Atterling Brolin, K., Malik, L., Kouam, C., Baker, B., Real, R., Step, K., Lange, L. M., Wu, L., Ostrozovicova, M., Andersh, K. M., Kung, P.-J., Mecheri, Y., Tay, Y.-W., Soundous Malek, B., Al Tassan, N., Teresa Perinan, M., Hong, S., Koretsky, M. J., Sargeant, L., Levine, K., Blauwendraat, C., Billingsley, K. J., Bandres-Ciga, S., Leonard, H. L., Bardien, S., Morris, H. R., Singleton, A. B., Nalls, M. A., Vitale, D., The Global Parkinson's Genetics Program
10.1101/2024.11.22.624040 — Posted: 2025-07-26
DIO-SPOTlight Transgenic Mouse to Functionally Monitor Protein Synthesis Regulated by the Integrated Stress Response
Oliver, M. L., Caffall, Z. F., Eatman, C. B., Faw, T. D., Calakos, N.
10.1101/2024.10.14.618312 — Posted: 2025-07-23
Enhanced beta power emerges from simulated parkinsonian primary motorcortex
Doherty, D. W., Chen, L., Smith, Y., Wichmann, T., Chu, H.-Y., Lytton, W. W.
10.1101/2024.05.23.595566 — Posted: 2025-07-20
Genotype-phenotype association study conducted on LARGE-PD reveals novel loci associated with Parkinson's Disease.
Leal, T. P., Waldo, E., Duarte-Zambrano, F., Inca-Martinez, M., Ramchandra, J., Chaparro-Solano, H. M., Anello, A. E., Borda, V., Gouveia, M. H., Teixeira-dos-Santos, D., Reyes-Perez, P., Gatto, E. M., Santos-Lobato, B. L., Eufraseo, G., Letro, G. H., Arboleda, G., Bernal-Pacheco, O., Orozco, J., Munoz, B., Chana-Cuevas, P., Aguillon, D., Moreno, S., Torrealba-Acosta, G., Lobo-Prada, T., Muller, V., Lopez Razquin, C. M., Braga-Neto, P., Duron, R., Rodriguez-Violante, M., Hernandez-Medrano, A. J., Cervantes-Arriaga, A., Martinez-Ramirez, D., Schuh, A. F. S., de Mello Rieder, C. R., Cornejo-Oliv
10.1101/2025.07.18.25331793 — Posted: 2025-07-18
Mapping the causal chain from genetic risk variants to lipid dysmetabolism in Parkinsons disease
DePaula, R., Kim, J., Rhinn, H., Saade, H., Chavez, F., Segura, T., Lozano, M. V., Etoundi, M., Silos, K., Korchina, V., doddapaneni, h. v., Venner, E., Masdeu, J. C., Pavlik, V., Yu, M. M., Lin, C.-Y. R., Jankovic, J., Buchman, A. S., Muzny, D. M., Gibbs, R. A., Elsea, S. H., Abeliovich, A., Lansbury, P., Vanegas-Arroyave, N., Shaw, C. A., Shulman, J. M.
10.1101/2025.07.14.25331535 — Posted: 2025-07-15
Rare but Relevant: Assessing Variants in Dystonia-linked Genes in Parkinson's Disease
Lange, L. M., Fang, Z.-H., Screven, L., Tan, A. H., Alcalay, R. N., Amouri, R., Bovenzi, R., Fenn, M., Frost, J. L. I., Jankovic, J., Jasaityte, S., Jaunmuktane, Z., Jeon, B., Keller Sarmiento, I. J., Krueger, R., Kuhlenbaeumer, G., Lin, C.-H., Pavelka, L., Perinan, M. T. M., Ben Sassi, S., Schirinzi, T., Shin, J. H., Shulman, J. M., Tay, Y. W., Uitti, R., Warner, T., Wszolek, Z. K., Wu, L., Wu, R.-M., Zeuner, K. E., Blauwendraat, C., Singleton, A., Mencacci, N. E., Morris, H., Lim, S.-Y., Lohmann, K., Klein, C., the Global Parkinson's Genetics Program (GP2)
10.1101/2025.07.10.25330831 — Posted: 2025-07-11
Cryo-electron tomography reveals the microtubule-bound form of inactive LRRK2
Chen, S., Basiashvili, T., Hutchings, J., Murillo, M. S., Suarez, A. V., Xiong, E., Louro, J. A., Leschziner, A. E., Villa, E.
10.1101/2024.06.18.599606 — Posted: 2025-07-10
Mitochondrial fission controls astrocyte morphogenesis and organization in the cortex
Salazar, M. P. R., Kolanukuduru, S., Ramirez, V., Lyu, B., Manigault, G., Sejourne, G., Sesaki, H., Yu, G., Eroglu, C.
10.1101/2024.10.22.619706 — Posted: 2025-07-03
EVscope: A Comprehensive Bioinformatics Pipeline for Accurate and Robust Analysis of Total RNA Sequencing from Extracellular Vesicles
Zhao, Y., Chintalapudi, H., Xu, Z., Liu, W., Hu, Y., Grassin, E., Song, M., Hong, S., Lee, L. P., Dong, X.
10.1101/2025.06.24.660984 — Posted: 2025-06-27

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