Channel:  Aligning Science Across Parkinson's (ASAP)

526 Articles

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Genetically Encoded and Modular SubCellular Organelle Probes (GEM-SCOPe) reveal lysosomal and mitochondrial dysfunction driven by PRKN knockout
Goldman, C., Kareva, T., Sarrafha, L., Sahasrabudhe, A., Schuldt, B. R., Ahfeldt, T., Blanchard, J. W.
10.1101/2024.05.21.594886 — Posted: 2025-06-02
Movement-related activity in the internal globus pallidus of the parkinsonian macaque
Kase, D., Zimnik, A. J., Han, Y., Harsch, D. R., Bacha, S., Cox, K. M., Bostan, A. C., Richardson, R. M., Turner, R. S.
10.1101/2024.08.29.610310 — Posted: 2025-05-30
Sex-dimorphic effects of neuromelanin buildup in rodent nigral dopamine neurons: implications for sex-biased vulnerability in Parkinson's disease
D'Addario, S. L., Massaro Cenere, M., Cossa, F., Scaricamazza, S., Nesci, V., D'Ottavio, G., Caprioli, D., Ferri, A., Vila, M., Ledonne, A., Mercuri, N. B.
10.1101/2025.04.18.649338 — Posted: 2025-05-27
Genome-wide assessment identifies novel runs of homozygosity linked to Parkinson's disease etiology across diverse ancestral populations
Step, K., Hernandez, C. F., Eltaraifee, E., Hernandez-Medrano, A. J., Kung, P.-J., Ostrozovicova, M., Zirra, A., Perez-Palma, E., Mencacci, N. E., Keller Sarmiento, I. J., Morris, H., Mata, I., Global Parkinson's Genetics Program, , Acosta-Uribe, J., Fang, Z.-H., Bandres Ciga, S.
10.1101/2025.05.21.25328076 — Posted: 2025-05-22
Drug Repurposing for Parkinson's Disease: A Large-Scale Multi-Cohort Study
Hu, Y., Liu, W., Waits, M., Zhao, Y., Olivero-Acosta, M. I., Zhang, L., Scherzer, C. R., Dong, X.
10.1101/2025.05.20.25327943 — Posted: 2025-05-21
Repetitive Levodopa Treatment Drives Cell Type-Specific Striatal Adaptations Associated With Progressive Dyskinesia in Parkinsonian Mice
Paz, R. M., Ryan, M. B., Marcott, P. F., Girasole, A. E., Faryean, J., Duong, V., Sridhar, S., Nelson, A. B.
10.1101/2025.05.16.654598 — Posted: 2025-05-21
Matters arising: Forced Symmetry Artifacts in a Prohibitin Complex Structure
Herrmann, E., Rose, K. M., Hurley, J. H.
10.1101/2025.05.16.653159 — Posted: 2025-05-20
Microbiome signature of Parkinson disease in healthy and genetically at-risk individuals
Menozzi, E., Meslier, V., Ren, Y., Geiger, M., Macnaughtan, J., Avenali, M., Gilles, M., Galandra, C., Mitrotti, P., Gallo, L., Famechon, A., Lucas Del Pozo, S., Mezabrovschi, R., Koletsi, S., Loefflad, N., Yalkic, S., Limbachiya, N., Blottiere, H., Morabito, C., David, A., Quinquis, B., Pons, N., Valzania, F., Cavallieri, F., Fioravanti, V., Toschi, G., Blandini, F., Ehrlich, S. D., Almeida, M., Schapira, A. H.
10.1101/2025.05.19.25327907 — Posted: 2025-05-19
End-product inhibition of the LRRK2-counteracting PPM1H phosphatase
Adhikari, A., Tripathi, A., Chiang, C. Y., Sherpa, P. L., Pfeffer, S. R.
10.1101/2025.05.16.654599 — Posted: 2025-05-17
Defect in hematopoiesis and embryonic lethality at midgestation of Vps13a/Vps13c double knockout mice
Xu, P., Mancuso, R. I., Leonzino, M., Zeiss, C. J., Krause, D. S., De Camilli, P.
10.1101/2025.05.09.653147 — Posted: 2025-05-13

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