Channel:  Aligning Science Across Parkinson's (ASAP)

514 Articles

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PD-linked LRRK2 G2019S mutation impairs astrocyte morphology and synapse maintenance via ERM hyperphosphorylation
Wang, S., Baumert, R., Sejourne, G., Sivadasan Bindu, D., Dimond, K., Sakers, K., Vazquez, L., Moore, J. L., Tan, C. X., Takano, T., Rodriguez, M. P., Brose, N., Bradley, L., Lessing, R., Soderling, S. H., La Spada, A. R., Eroglu, C.
10.1101/2023.04.09.536178 — Posted: 2025-04-29
Differential memory enrichment of cytotoxic CD4 T cells in Parkinson's disease patients reactive to α-synuclein
Freuchet, A., Johansson, E., Frazier, A., Litvan, I., Goldman, J. G., Alcalay, R. N., Sulzer, D., Lindestam Arlehamn, C. S., Sette, A.
10.1101/2025.04.21.649867 — Posted: 2025-04-24
T cell responses towards PINK1 and α-synuclein are elevated in prodromal Parkinson's disease
Johansson, E., Freuchet, A., Williams, G. P., Michealis, T., Frazier, A., Litvan, I., Goldman, J. G., Alcalay, R. N., Standaert, D. G., Amara, A. W., Stover, N., Fon, E. A., Postuma, R. B., Sidney, J., Sulzer, D., Lindestam Arlehamn, C. S., Sette, A.
10.1101/2025.04.21.649871 — Posted: 2025-04-24
AI-directed voxel extraction and volume EM identify intrusions as sites of mitochondrial contact
Padman, B. S., Lindblom, R. S. J., Lazarou, M.
10.1101/2024.11.20.624606 — Posted: 2025-04-16
Does COMT Play a Role in Parkinson's Disease Susceptibility Across Diverse Ancestral Populations?
Martin-Bornez, M., Shar, N., Nour, M. A., Murphy, D., Elsayed, I., N, M. S., Nwaokorie, F., Olusanya, A., Kuznetsov, N., Bandres-Ciga, S., Noyce, A. J., Iwaki, H., Jones, L., Gomez-Garre, P., Mir, P., The Global Parkinson's Genetics Program (GP2), , Perinan, M. T.
10.1101/2025.04.11.25325572 — Posted: 2025-04-11
Activity-Dependent Remodeling of Corticostriatal Axonal Boutons During Motor Learning
Sheng, M., Lu, D., Sheng, K., Ding, J.
10.1101/2024.06.10.598366 — Posted: 2025-04-09
HyDrop v2: Scalable atlas construction for training sequence-to-function models
Dickmänken, H., Wojno, M., Theunis, K., Eksi, E. C., Mahieu, L., Christiaens, V., Kempynck, N., De Rop, F. V., Roels, N., Spanier, K. I., Vandepoel, R., Hulselmans, G. J., Poovathingal, S., Aerts, S.
10.1101/2025.04.02.646792 — Posted: 2025-04-05
CREsted: modeling genomic and synthetic cell type-specific enhancers across tissues and species
Kempynck, N., De Winter, S., Blaauw, C. H., Konstantakos, V., Dieltiens, S., Eksi, E. C., Bercier, V., Taskiran, I. I., Hulselmans, G., Spanier, K., Christiaens, V., Van Den Bosch, L., Mahieu, L., Aerts, S.
10.1101/2025.04.02.646812 — Posted: 2025-04-03
BLTP3A is associated with membranes of the late endocytic pathway and is an effector of CASM
Hanna, M. G., Rodriguez Cruz, H. O., Fujise, K., Wu, Y., Xu, C. S., Pang, S., Zhuoning, L., Monetti, M., De Camilli, P.
10.1101/2024.09.28.615015 — Posted: 2025-04-03
Baseline α-synuclein seeding activity and disease progression in sporadic and genetic Parkinson's disease in the PPMI cohort
Schumacher, J. G., Zhang, X., Macklin, E. A., Wang, J., Bayati, A., Dijkstra, J. M., Watanabe, H., Schwarzschild, M. A., Cortese, M., Zhang, X., Chen, X.
10.1101/2024.09.27.24311107 — Posted: 2025-04-02

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