Channel:  Aligning Science Across Parkinson's (ASAP)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

239 Articles

Sst+ GPi output neurons provide direct feedback to key nodes of the basal ganglia and drive behavioral flexibility.
Weglage, M., Aehrlund Richter, S., Skara, V., Lazaridis, I., Meletis, K.
10.1101/2022.03.16.484460 — Posted: 2022-03-18
Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation
Ren, X., Nguyen, T. N., Lam, W. K., Buffalo, C. Z., Lazarou, M., Yokom, A. L., Hurley, J. H.
10.1101/2022.07.12.499634 — Posted: 2022-07-13
Integrated multi-cohort analysis of the Parkinson's disease gut metagenome
Boktor, J. C., Sharon, G., Verhagen Metman, L. A., Hall, D. A., Engen, P. A., Zreloff, Z., Hakim, D. J., Bostick, J. W., Ousey, J., Lange, D., Humphrey, G., Ackermann, G., Carlin, M., Knight, R., Keshavarzian, A., Mazmanian, S. K.
10.1101/2022.07.20.500694 — Posted: 2022-07-21
A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice
Abdel-Haq, R., Schlachetzki, J. C. M., Boktor, J. C., Cantu-Jungles, T. M., Thron, T., Zhang, M., Bostick, J. W., Khazaei, T., Chilakala, S., Morais, L. H., Humphrey, G., Keshavarzian, A., Katz, J. E., Thomson, M., Knight, R., Gradinaru, V., Hamaker, B. R., Glass, C. K., Mazmanian, S. K.
10.1101/2022.06.27.497828 — Posted: 2022-06-30
Genome-wide determinants of mortality and motor progression in Parkinson's disease
Tan, M. M., Lawton, M. A., Pollard, M. I., Brown, E. E., Real, R., Martinez, A., Bekadar, S., Jabbari, E., Reynolds, R. H., Iwaki, H., Blauwendraat, C., Kanavou, S., Hubbard, L., Malek, N., Grosset, K. A., Bajaj, N., Barker, R. A., Burn, D. J., Bresner, C., Foltynie, T., Wood, N. W., Williams-Gray, C. H., Andreassen, O. A., Toft, M., Elbaz, A., Artaud, F., Brice, A., Corvol, J.-C., Aasly, J., Farrer, M. J., Nalls, M. A., Singleton, A. B., Williams, N. M., Ben-Shlomo, Y., Hardy, J., Hu, M. T., Grosset, D. G., Shoai, M., Pihlstrom, L., Morris, H. R.
10.1101/2022.07.07.22277297 — Posted: 2023-06-09
Structural and functional landscape of α-synuclein fibril conformations amplified from cerebrospinal fluid
Sokratian, A., Zhou, Y., Xu, E., Viverette, E., Dillard, L., Yuan, Y., Li, J., Matarangas, A., Bouvette, J., Borgnia, M. J., Bartesaghi, A., West, A.
10.1101/2022.07.13.499896 — Posted: 2022-07-13
Nicotine-mediated rescue of α-synuclein toxicity requires synaptic vesicle glycoprotein 2
Olsen, A. L., Clemens, S. G., Feany, M. B.
10.1101/2022.07.26.501592 — Posted: 2022-07-28
DOPA pheomelanin is increased in nigral neuromelanin of Parkinson's disease and it exacerbates alpha-synuclein neurotoxicity
Cai, W., Wakamatsu, K., Zucca, F., Yang, K., Mohamadzadehhonarvar, N., Srivastava, P., Holly, G., Casella, L., Ito, S., Zecca, L., Chen, X.
10.1101/2022.06.30.22277063 — Posted: 2022-07-03
In vivo reduction of age-dependent neuromelanin accumulation mitigates features of Parkinson's disease
Gonzalez-Sepulveda, M., Compte, J., Cuadros, T., Nicolau, A., Guillard-Sirieix, C., Penuelas, N., Lorente-Picon, M., Parent, A., Romero-Gimenez, J., Cladera-Sastre, J. M., Laguna, A., Vila, M.
10.1101/2022.08.08.503142 — Posted: 2022-08-11
Unconventional Initiation of PINK1/Parkin Mitophagy by Optineurin
Nguyen, T. N., Sawa-makarska, J., Khuu, G., Lam, W. K., Adriaenssens, E., Fracchiolla, D., Shoebridge, S., Padman, B. S., Skulsuppaisarn, M., Lindblom, R. S. J., Martens, S., Lazarou, M.
10.1101/2022.08.14.503930 — Posted: 2023-05-02

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