COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

30,553 Articles (22,400 medRxiv, 8,153 bioRxiv)

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Nirmatrelvir Resistant SARS-CoV-2 Variants with High Fitness in Vitro
Zhou, Y., Gammeltoft, K. A., Ryberg, L. A., Pham, L. V., Fahnoe, U., Binderup, A., Hernandez, C. R. D., Offersgaard, A., Fernandez-Antunez, C., Peters, G. H. J., Ramirez, S., Bukh, J., Gottwein, J. M.
10.1101/2022.06.06.494921 — Posted: 2022-06-07
The substitutions L50F, E166A and L167F in SARS-CoV-2 3CLpro are selected by a protease inhibitor in vitro and confer resistance to nirmatrelvir
Jochmans, D., Liu, C., Donckers, K., Stoycheva, A., Boland, S., Stevens, S. K., De Vita, C., Vanmechelen, B., Maes, P., Trüeb, B. S., Ebert, N., Thiel, V., De Jonghe, S., Vangeel, L., Bardiot, D., Jekle, A., Blatt, L. M., Beigelman, L., Symons, J. A., Raboisson, P., Chaltin, P., Marchand, A., Neyts, J., Deval, J., Vandyck, K.
10.1101/2022.06.07.495116 — Posted: 2022-06-07
Development of an Escape-resistant SARS CoV-2 Neutralizing Synthetic Nanobody
Dormeshkin, D., Shapira, M., Dubovik, S., Kavaleuski, A., Katsin, M., Migas, A., Meleshko, A., Semyonov, S.
10.1101/2022.06.07.495065 — Posted: 2022-06-07
Within-host diversity improves phylogenetic and transmission reconstruction of SARS-CoV-2 outbreaks
Ortiz, A. T., Kendall, M., Storey, N., Hatcher, J., Dunn, H., Roy, S., Williams, R., Williams, C., Goldstein, R. A., Didelot, X., Harris, K., Breuer, J., Grandjean, L.
10.1101/2022.06.07.495142 — Posted: 2022-06-07
GABA-receptors are a new druggable target for limiting disease severity, lung viral load, and death in SARS-CoV-2 infected mice
Tian, J., Dillion, B., Henley, J., Comai, L., Kaufman, D.
10.1101/2022.06.07.494579 — Posted: 2022-06-07
Predicting clinical outcomes of SARS-CoV-2 drug treatments with a high throughput human airway on chip platform
Fisher, C. R., Medie, F. M., Luu, R. J., Quezada, L. L., Gaibler, R. B., Mulhern, T. J., Rubio, L. D., Marr, E. E., Gabriel, E. P., Borenstein, J. T., Gard, A. L.
10.1101/2022.06.07.495101 — Posted: 2022-06-07
Neutralization of Omicron sublineages and Deltacron SARS-CoV-2 by 3 doses of BNT162b2 vaccine or BA.1 infection
Kurhade, C., Zou, j., Xia, H., Liu, M., Yang, Q., Cutler, M., Cooper, D., Muik, A., Sahin, U., Jansen, K. U., Ren, P., Xie, X., Shi, P.-Y.
10.1101/2022.06.05.494889 — Posted: 2022-06-07
Post-acute COVID-19 cognitive impairment and decline uniquely associate with kynurenine pathway activation: a longitudinal observational study
Cysique, L. A., Jakabek, D., Bracken, S. G., Allen-Davidian, Y., Heng, B., Chow, S., Dehhaghi, M., Staats-Pires, A., Darley, D. R., Byrne, A., Phetsouphanh, C., Kelleher, A., Dore, G., Matthews, G. V., Guillemin, G., Brew, B. J.
10.1101/2022.06.07.22276020 — Posted: 2022-06-07
Non-pharmacological therapies for post-viral syndromes, including Long COVID: A systematic review
Chandan, J. S., Brown, K. R., Simms-Williams, N., Bashir, N. Z., Camaradou, J., Heining, D., Turner, G. M., Rivera, S. C., Hotham, R., Minhas, S., Niratharakumar, K., Sivan, M., Khunti, K., Raindi, D., Marwaha, S., Hughes, S. E., McMullan, C., Marshall, T., Calvert, M. J., Haroon, S., Aiyegbusi, O. L.
10.1101/2022.06.07.22276080 — Posted: 2022-06-07
Precarious employment and associations with health during COVID-19: a nationally representative survey in Wales, UK
Gray, B. J., Kyle, R. G., Isherwood, K. R., Humphreys, C., Griffiths, M. L., Davies, A. R.
10.1101/2022.06.07.22275493 — Posted: 2022-06-07

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).