COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

30,557 Articles (22,400 medRxiv, 8,157 bioRxiv)

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Biophysical modeling of the SARS-CoV-2 viral cycle reveals ideal antiviral targets
Castle, B. T., Dock, C., Hemmat, M., Kline, S., Tignanelli, C., Rajasingham, R., Masopust, D., Provenzano, P., Langlois, R., Schacker, T., Haase, A., Odde, D. J.
10.1101/2020.05.22.111237 — Posted: 2020-05-23
Intestinal inflammation modulates the expression of ACE2 and TMPRSS2 and potentially overlaps with the pathogenesis of SARS-CoV-2 related disease
Suarez-Farinas, M., Tokuyama, M., Wei, G., Huang, R., Livanos, A., Jha, D., Levescot, A., Kosoy, R., Irizar, H., Cording, S., Wang, W., Ungaro, R., Di Narzo, A., Martinez, G., Suprun, M., Corley, M. J., Stojmirovic, A., Houten, S., Curran, M., Brodmerkel, C., Perrigoue, J., Friedman, J. R., Hao, K., Schadt, E. E., Zhu, J., Ko, H. M., Cho, J., Dubinsky, M. C., Sands, B. E., Ndhlovu, L., Cerf-Bensusan, N., Kasarskis, A., Colombel, J.-F., Harpaz, N., Argmann, C., Mehandru, S.
10.1101/2020.05.21.109124 — Posted: 2020-05-23 Discussion: Onsite | Offsite
Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions
Mathew, D., Giles, J. R., Baxter, A. E., Greenplate, A. R., Wu, J. E., Alanio, C., Oldridge, D. A., Kuri-Cervantes, L., Pampena, M. B., D'Andrea, K., Manne, S., Chen, Z., Huang, Y. J., Reilly, J. P., Weisman, A. R., Ittner, C. A. G., Kuthuru, O., Dougherty, J., Nzingha, K., Han, N., Kim, J., Pattekar, A., Goodwin, E. C., Anderson, E. M., Weirick, M. E., Gouma, S., Arevalo, C. P., Bolton, M. J., Chen, F., Lacey, S. F., Hensley, S. E., Apostolidis, S., Huang, A. C., Vella, L. A., UPenn COVID Processing Unit, , Betts, M. R., Meyer, N. J., Wherry, E. J.
10.1101/2020.05.20.106401 — Posted: 2020-05-23 Discussion: Onsite | Offsite
The emergence of SARS-CoV-2 in Europe and the US
Worobey, M., Pekar, J., Larsen, B. B., Nelson, M. I., Hill, V., Joy, J. B., Rambaut, A., Suchard, M. A., Wertheim, J. O., Lemey, P.
10.1101/2020.05.21.109322 — Posted: 2020-05-23 Discussion: Onsite
Lung epithelial stem cells express SARS-CoV-2 entry factors: implications for COVID-19
Valyaeva, A. A., Zharikova, A. A., Kasianov, A. S., Vassetzky, Y. S., Sheval, E. V.
10.1101/2020.05.23.107334 — Posted: 2020-05-23
In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19
Phan, I. Q., Subramanian, S., Kim, D., Carter, L., King, N., Anishchenko, I., Barrett, L. K., Craig, J. K., Tillery, L., Shek, R., Harrington, W. E., Koelle, D. M., Wald, A., Boonyaratanakornkit, J., Isoherranen, N., Greninger, A. L., Jerome, K. R., Chu, H., Staker, B., Myler, P. J., Van Voorhis, W. C.
10.1101/2020.05.22.111526 — Posted: 2020-05-23
Targeting the SARS-CoV-2 Main Protease to Repurpose Drugs for COVID-19
Vatansever, E. C., Yang, K., Kratch, K. C., Drelich, A., Cho, C.-C., Mellot, D. M., Xu, S., Tseng, C.-T. K., Liu, W. R.
10.1101/2020.05.23.112235 — Posted: 2020-05-23
A Modular Microarray Imaging System for Highly Specific COVID-19 Antibody Testing
Hedde, P. N., Abram, T. J., Jain, A., Nakajima, R., Ramiro de Assis, R., Pearce, T., Jasinskas, A., Toosky, M. N., Khan, S., Felgner, P. L., Gratton, E., Zhao, W.
10.1101/2020.05.22.111518 — Posted: 2020-05-23
Predicting wildlife hosts of betacoronaviruses for SARS-CoV-2 sampling prioritization
Becker, D., Albery, G. F., Sjodin, A. R., Poisot, T., Dallas, T., Eskew, E. A., Farrell, M. J., Guth, S., Han, B. A., Simmons, N. B., Carlson, C. J.
10.1101/2020.05.22.111344 — Posted: 2020-05-23 Discussion: Offsite
Age-related expression of SARS-CoV-2 priming protease TMPRSS2 in the developing lung
Schuler, B. A., Habermann, A. C., Plosa, E. J., Taylor, C. J., Jetter, C. S., Kapp, M. E., Benjamin, J., Gulleman, P., Nichols, D. S., Braunstein, L. Z., Koval, M. H., Guttentag, S. H., Blackwell, T. S., Vanderbilt COVID-19 Consortium Cohort, , Webber, S. A., Banovich, N., Kropski, J. A., Sucre, J. M., HCA Lung Biological Network
10.1101/2020.05.22.111187 — Posted: 2020-05-23

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).