COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,300 Articles (22,772 medRxiv, 8,528 bioRxiv)

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Positive selection within the genomes of SARS-CoV-2 and other Coronaviruses independent of impact on protein function
Berrio, A., Gartner, V., Wray, G. A.
10.1101/2020.09.16.300038 — Posted: 2020-09-16
Lopinavir-ritonavir is not an effective inhibitor of the main protease activity of SARS-CoV-2 in vitro
Jang, M., Park, Y.-I., Park, R., Cha, Y.-E., Namkoong, S., Lee, J. I., Park, J.
10.1101/2020.09.16.299800 — Posted: 2020-09-16 Discussion: Onsite
Ebselen, disulfiram, carmofur, PX-12, tideglusib, and shikonin are non-specific promiscuous SARS-CoV-2 main protease inhibitors
Ma, C., Hu, Y., Townsend, J. A., Lagarias, P., Marty, M. T., Kolocouris, A., Wang, J.
10.1101/2020.09.15.299164 — Posted: 2020-09-16
Evaluation of nafamostat mesylate safety and inhibition of SARS-CoV-2 replication using a 3-dimensional human airway epithelia model
Kirkpatrick, L., Millard, J.
10.1101/2020.09.16.300483 — Posted: 2020-09-16
Bromelain Inhibits SARS-CoV-2 Infection in VeroE6 Cells
Sagar, S., Rathinavel, A. K., Lutz, W. E., Struble, L. R., Khurana, S., Schnaubelt, A. T., Mishra, N. K., Guda, C., Broadhurst, M. J., Reid, S. P., Bayles, K. W., Borgstahl, G. E. O., Radhakrishnan, P.
10.1101/2020.09.16.297366 — Posted: 2020-09-16
Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques
Hoang, T. N., Pino, M., Boddapati, A. K., Viox, E. G., Starke, C. E., Upadhyay, A. A., Gumber, S., Busman-Sahay, K., Strongin, Z., Harper, J. L., Tharp, G. K., Pellegrini, K. L., Kirejczyk, S., Zandi, K., Tao, S., Horton, T. R., Beagle, E. N., Mahar, E. A., Lee, M. Y., Cohen, J., Jean, S., Wood, J. S., Connor-Stroud, F., Stammen, R. L., Delmas, O. M., Wang, S., Cooney, K. A., Sayegh, M. N., Wang, L., Weiskopf, D., Filev, P. D., Waggoner, J., Piantadosi, A., Kasturi, S. P., Al-Shakhshir, H., Ribeiro, S. P., Sekaly, R. P., Levit, R. D., Estes, J. D., Vanderford, T. H., Schinazi, R. F., Bosinger, S. E., Paiardini, M.
10.1101/2020.09.16.300277 — Posted: 2020-09-16
Structure Model Analysis Of Phosphorylation Dependent Binding And Sequestration Of SARS-COV-2 Encoded Nucleocapsid Protein By Protein 14-3-3
Tung, H. Y. L., Limtung, P.
10.1101/2020.09.16.299362 — Posted: 2020-09-16
Efficient production of Moloney murine leukemia virus-like particles pseudotyped with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike protein
Caruso, M., Roy, S., Ghani, K., de Campos-Lima, P. O.
10.1101/2020.09.16.298992 — Posted: 2020-09-16
Characterisation of protease activity during SARS-CoV-2 infection identifies novel viral cleavage sites and cellular targets for drug repurposing
Meyer, B., Chiaravalli, J., Brownridge, P., Bryne, D. P., Daly, L. A., Agou, F., Eyers, C. E., Eyers, P. A., Vignuzzi, M., Emmott, E.
10.1101/2020.09.16.297945 — Posted: 2020-09-16 Discussion: Onsite
Mouse model for testing SARS-CoV-2 antivirals: Pharmacokinetics
Scherf-Clavel, O., Kinzig, M., Friedl, B., Kaczmarek, E., Feja, M., Gernert, M., Richter, F., Hoehl, R., Nau, R., Holzgrabe, U., Soergel, F.
10.1101/2020.09.16.299537 — Posted: 2020-09-16

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).