COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,187 Articles (22,713 medRxiv, 8,474 bioRxiv)

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The mRNA-LNP platform's lipid nanoparticle component used in preclinical vaccine studies is highly inflammatory
Ndeupen, S., Qin, Z., Jacobsen, S., Gibb, M., Estanbouli, H., Bouteau, A., Cardenas, J., Uthra, B., Wang, Y., Gu, J., Igyarto, B. Z.
10.1101/2021.03.04.430128 — Posted: 2021-03-04 Discussion: Onsite
SARS-CoV-2 variant with higher affinity to ACE2 shows reduced sera neutralization susceptibility
Vogel, M., Chang, X., Sousa Augusto, G., Mohsen, M. O., Speiser, D. E., Bachmann, M. F.
10.1101/2021.03.04.433887 — Posted: 2021-03-04
Optimization of an LNP-mRNA vaccine candidate targeting SARS-CoV-2 receptor-binding domain
Kobiyama, K., Imai, M., Jounai, N., Nakayama, M., Hioki, K., Iwatsuki-Horimoto, K., Yamayoshi, S., Tsuchida, J., Niwa, T., Suzuki, T., Ito, M., Yamada, S., Watanabe, T., Kiso, M., Negishi, H., Temizoz, B., Ishigaki, H., Kitagawa, Y., Nguyen, C. T., Itoh, Y., Takeshita, F., Kawaoka, Y., Ishii, K. J.
10.1101/2021.03.04.433852 — Posted: 2021-03-04
Comparing SARS-CoV-2 case rates between pupils, teachers and the general population: results from Ger-many
Koestner, C., Letzel, S., Eggert, V., Beutel, T., Dietz, P.
10.1101/2021.03.04.21252877 — Posted: 2021-03-04
Saliva testing is accurate for early-stage and presymptomatic COVID-19
Johnson, A. J., Zhou, S., Hoops, S. L., Hillmann, B., Schomaker, M., Kincaid, R., Daniel, J., Beckman, K., Yohe, S., Nelson, A. C.
10.1101/2021.03.03.21252830 — Posted: 2021-03-04
Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters
Dalvie, N. C., Rodriguez-Aponte, S. A., Hartwell, B. L., Tostanoski, L. H., Biedermann, A. M., Crowell, L. E., Kaur, K., Kumru, O., Carter, L., Yu, J., Chang, A., McMahan, K., Courant, T., Lebas, C., Lemnios, A. A., Rodrigues, K. A., Silva, M., Johnston, R. S., Naranjo, C. A., Tracey, M. K., Brady, J. R., Whittaker, C. A., Yun, D., Kar, S., Porto, M., Lok, M., Andersen, H., Lewis, M. G., Love, K. R., Camp, D. L., Silverman, J. M., Kleanthous, H., Joshi, S. B., Volkin, D. B., Dubois, P. M., Collin, N., King, N. P., Barouch, D. H., Irvine, D. J., Love, J. C.
10.1101/2021.03.03.433558 — Posted: 2021-03-04
Ribosome-profiling reveals restricted post transcriptional ex-pression of antiviral cytokines and transcription factors during SARS-CoV-2 infection
Alexander, M. R., Brice, A. M., Jansen Van Vuren, P., Rootes, C., Tribolet, L., Cowled, C., Bean, A. G. D., Stewart, C. R.
10.1101/2021.03.03.433675 — Posted: 2021-03-04
Ethnicity and COVID-19 outcomes among healthcare workers in the United Kingdom: UK-REACH ethico-legal research, qualitative research on healthcare workers' experiences, and stakeholder engagement protocol
Gogoi, M., Reed-Berendt, R., Al-Oraibi, A., Hassan, O., Wobi, F., Gupta, A., Abubakar, I., Dove, E., Nellums, L., Pareek, M.
10.1101/2021.03.03.21252737 — Posted: 2021-03-03
Upper respiratory tract SARS-CoV-2 RNA loads in symptomatic and asymptomatic children and adults
Costa, R., Bueno, F., Albert, E., Torres, I., Carbonell-Sahuquillo, S., Barres-Fernandez, A., Sanchez, D., Padron, C., Colomina, J., Lazaro-Carreno, M. I., Breton-Martinez, J. R., Martinez-Costa, C., Navarro, D.
10.1101/2021.03.03.21252814 — Posted: 2021-03-03
SARS-CoV-2 Sequence Characteristics of COVID-19 Persistence and Reinfection
Choudhary, M. C., Crain, C. R., Qiu, X., Hanage, W., Li, J. Z.
10.1101/2021.03.02.21252750 — Posted: 2021-03-03

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).