COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

29,117 Articles (21,576 medRxiv, 7,541 bioRxiv)

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The method utilized to purify the SARS-CoV-2 N protein can affect its molecular properties
Tarczewska, A., Kolonko-Adamska, M., Zarebski, M., Dobrucki, J. W., Ozyhar, A., Greb-Markiewicz, B.
10.1101/2021.05.03.442392 — Posted: 2021-05-04
Possible role of accessory proteins in the viral replication for the 20I/501Y.V1 (B.1.1.7) SARS-CoV-2 variant
Nyayanit, D. A., Sarkale, P., Shete-Aich, A., Kumar, A., Patil, S., Majumdar, T., Baradkar, S., Gawande, P., Mohandas, S., Yadav, P. D.
10.1101/2021.04.30.442222 — Posted: 2021-05-04
The Immunological Factors Predisposing To Severe COVID-19 Are Already Present In Healthy Elderly And Men
Kilic, G., Bulut, O., Jaeger, M., ter Horst, R., Koeken, V., Moorlag, S. J. C. F. M., Mourits, V., de Bree, C., Dominguez-Andres, J., Joosten, L. A. B., Netea, M.
10.1101/2021.04.30.442229 — Posted: 2021-05-04
Vitamin C inhibits SARS coronavirus-2 main protease essential for viral replication
Malla, T. N., Pandey, S., Poudyal, I., Aldama, L., Feliz, D., Noda, M., Phillips, G. N., Stojkovic, E. A., Schmidt, M.
10.1101/2021.05.02.442358 — Posted: 2021-05-03
ACE2 expression in rat brain: implications for COVID-19 associated neurological manifestations
Hernandez, V. S., Zetter, M. A., Guerra, E. C., Hernandez-Araiza, I., Karuzin, N., Hernandez-Perez, O. R., Eiden, L. E., Zhang, L.
10.1101/2021.05.01.442293 — Posted: 2021-05-03
In silico and in vitro Demonstration of Homoharrintonine Antagonism of RBD-ACE2 Binding and its Anti-inflammatory and anti-thrombogenic Properties in a 3D human vascular lung model
Saxena, S., Meher, K., Rotella, M., Vangala, S., Chandran, S., Malhotra, N., Palakodeti, R., Voleti, S., Saxena, U.
10.1101/2021.05.02.442384 — Posted: 2021-05-03
The temperature-dependent conformational ensemble of SARS-CoV-2 main protease (Mpro)
Ebrahim, A., Riley, B. T., Kumaran, D., Andi, B., Fuchs, M. R., McSweeney, S., Keedy, D. A.
10.1101/2021.05.03.437411 — Posted: 2021-05-03
SARS-CoV-2 Genome Sequencing Methods Differ In Their Ability To Detect Variants From Low Viral Load Samples
Lam, C., Gray, K.-A., Gall, M., Sadsad, R., Arnott, A., Johnson-Mackinnon, J., Fong, W., Basile, K., Kok, J., Dwyer, D. E., Sintchenko, V., Rockett, R. J.
10.1101/2021.05.01.442304 — Posted: 2021-05-03
Human organoid systems reveal in vitro correlates of fitness for SARS-CoV-2 B.1.1.7
Lamers, M. M., Breugem, T. I., Mykytyn, A. Z., Wang, Y., Groen, N., Knoops, K., Schipper, D., van der Vaart, J., Koopman, C. D., Zhang, J., Wu, D. C., van den Doel, P. B., Bestebroer, T., GeurtsvanKessel, C. C., Peters, P. J., Muraro, M. J., Clevers, H., Wu, N. C., Haagmans, B. L.
10.1101/2021.05.03.441080 — Posted: 2021-05-03
Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19
Apostolidis, S. A., Sarkar, A., Giannini, H. M., Goel, R. R., Mathew, D., Suzuki, A., Baxter, A. E., Greenplate, A. R., Alanio, C., Abdel-Hakeem, M., Oldridge, D. A., Giles, J. R., Wu, J. E., Chen, Z., Huang, Y. J., Pattekar, A., Manne, S., Kuthuru, O., Dougherty, J., Weiderhold, B., Weisman, A. R., Ittner, C. A. G., Gouma, S., Dunbar, D., Frank, I., Huang, A. C., Vella, L. A., The UPenn COVID Processing Unit, , Reilly, J. P., Hensley, S. E., Rauova, L., Zhao, L., Meyer, N. J., Poncz, M., Abrams, C. S., Wherry, E. J.
10.1101/2021.05.01.442279 — Posted: 2021-05-03

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Subject Areas
* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).