COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,301 Articles (22,772 medRxiv, 8,529 bioRxiv)

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Improved binding affinity of the Omicron's spike protein with hACE2 receptor is the key factor behind its increased virulence
Kumar, R., Arul, M. N., Srivastava, V.
10.1101/2021.12.28.474338 — Posted: 2021-12-28
Intranasal inhibitor blocks Omicron and other variants of SARS-CoV-2
Mäkelä, A. R., Ugurlu, H., Hannula, L., Salminen, P., Kant, R., Fagerlund, R., Haveri, A., Strandin, T., Kareinen, L., Hepojoki, J., Levanov, L., Pasternack, A., Naves, R. A., Ritvos, O., Österlund, P., Sironen, T., Vapalahti, O., Kipar, A., Huiskonen, J. T., Rissanen, I., Saksela, K.
10.1101/2021.12.28.474326 — Posted: 2021-12-28
Effect of nebulised BromAc(R) on rheology of artificial sputum: relevance to muco-obstructive respiratory diseases including COVID-19
Pillai, K., Mekkawy, A. H., Valle, S., Akhter, J., Morris, D. L.
10.1101/2021.12.28.474344 — Posted: 2021-12-28
Evaluation of maternal-infant dyad inflammatory cytokines in pregnancies affected by maternal SARS-CoV-2 infection in early and late gestation.
Taglauer, E., Dhole, Y., Boateng, J., Snyder-Cappione, J. E., Parker, S. E., Clarke, K., Juttukonda, L., Devera, J., Hunnewell, J., Barnett, E., Jia, H., Yarrington, C., Sabharwal, V., Wachman, E.
10.1101/2021.12.26.472655 — Posted: 2021-12-28
Vaccine-breakthrough infection by the SARS-CoV-2 Omicron variant elicits broadly cross-reactive immune responses
Zhou, R., To, K. K.-W., Peng, Q., Chan, J. M.-C., Huang, H., Yang, D., Lam, B. H.-S., Chuang, V. W.-M., Cai, J.-P., Liu, N., Au, K.-K., Tsang, O. T.-Y., Yuen, K.-Y., Chen, Z.
10.1101/2021.12.27.474218 — Posted: 2021-12-28
Structural analysis of the Spike of the Omicron SARS-COV-2 variant by Cryo-EM and implications for immune evasion
Ni, D., Lau, K., Turelli, P., Raclot, C., Beckert, B., Nazarov, S., Pojer, F., Myasnikov, A., Stahlberg, H., Trono, D.
10.1101/2021.12.27.474250 — Posted: 2021-12-28
Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529
Zhou, T., Wang, L., Misasi, J., Pegu, A., Zhang, Y., Harris, D. R., Olia, A. S., Talana, C. A., Yang, E. S., Chen, M., Choe, M., Shi, W., Teng, I.-T., Creanga, A., Jenkins, C., Leung, K., Liu, T., Stancofski, E.-S. D., Stephens, T., Zhang, B., Tsybovsky, Y., Graham, B., Mascola, J. R., Sullivan, N., Kwong, P. D.
10.1101/2021.12.27.474307 — Posted: 2021-12-28
Booster vaccines protect hamsters with waning immunity from Delta VOC infection, disease, and transmission
Potts, K. G., Noyce, R. S., Gafuik, C., John, C. M., Todesco, H. M., De Heuvel, E., Favis, N., Kelly, M. M., Evans, D. H., Mahoney, D. J.
10.1101/2021.12.27.474282 — Posted: 2021-12-28
Deciphering the quality of SARS-CoV-2 specific T-cell response associated with disease severity, immune memory and heterologous response
Perez-Gomez, A., Gasca-Capote, M. C., Vitalle, J., Ostos, F. J., Serna-Gallego, A., Trujillo-Rodriguez, M., Munoz-Muela, E., Giraldez-Perez, T., Praena-Segovia, J., Navarro-Amuedo, M. D., Paniagua-Garcia, M., Garcia-Gutierrez, M., Aguilar-Guisado, M., Rivas-Jeremias, I., Jimenez-Leon, M. R., Bachiller, S., Fernandez-Villar, A., Perez-Gonzalez, A., Gutierrez-Valencia, A., Rafii-El-Idrissi Benhnia, M., Weiskopf, D., Sette, A., Lopez-Cortes, L. F., Poveda, E., Ruiz-Mateos, E.
10.1101/2021.12.28.474325 — Posted: 2021-12-28
SARS-CoV-2 vaccination induces immunological memory able to cross-recognize variants from Alpha to Omicron
Tarke, A., Coelho, C. H., Zhang, Z., Dan, J. M., Yu, E. D., Methot, N., Bloom, N. I., Goodwin, B., Phillips, E., Mallal, S., Sidney, J., Filaci, G., Weiskopf, D., da Silva Antunes, R., Crotty, S., Grifoni, A., Sette, A.
10.1101/2021.12.28.474333 — Posted: 2021-12-28

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).