Channel: Albert Einstein College of Medicine

This collection includes bioRxiv and medRxiv papers from authors at Albert Einstein College of Medicine.

998 Articles

A single-cell transposable element atlas of human cell identity

Reyes-Gopar, H., Marston, J. L., Singh, B., Greenig, M., Lin, J., Ostrowski, M. A., Randall, K. N., Sandoval-Motta, S., Dopkins, N., Lawrence, E., O'Mara, M. M., Fei, T., Duarte, R. R. R., Powell, T. R., Hernandez-Lemus, E., Iniguez, L. P., Nixon, D. F., Bendall, M. L.

10.1101/2023.12.28.573568 — Posted: 2023-12-28

Synergistic insulation of regulatory domains by developmental genes and clusters of CTCF sites

Ealo, T., Sanchez-Gaya, V., Respuela, P., Munoz-San Martin, M., Martin-Batista, E., Haro, E., Rada-Iglesias, A.

10.1101/2023.12.15.571760 — Posted: 2023-12-16

Cryo-EM Unveils the Processivity Mechanism of Kinesin KIF1A and the Impact of its Pathogenic Variant P305L

Benoit, M. P. M. H., Rao, L., Asenjo, A. B., Gennerich, A., Sosa, H. J.

10.1101/2023.02.02.526913 — Posted: 2023-12-15

Metacell-based differential expression analysis identifies cell type specific temporal gene response programs in COVID-19 patient PBMCs

O'Leary, K., Zheng, D.

10.1101/2023.12.14.571774 — Posted: 2023-12-15

A CAG repeat threshold for therapeutics targeting somatic instability in Huntington's disease

Aldous, S. G., Smith, E. J., Landles, C., Osborne, G. F., Canibano-Pico, M., Nita, I. M., Phillips, J., Zhang, Y., Jin, B., Hirst, M. B., Benn, C. L., Bond, B. C., Edelmann, W., Greene, J. R., Bates, G. P.

10.1101/2023.12.15.571088 — Posted: 2023-12-15

Targetable leukemia dependency on noncanonical PI3Kγ signaling

Luo, Q., Raulston, E. G., Prado, M. A., Wu, X., Gritsman, K., Booth, C. A. G., Xu, R., van Galen, P., Doench, J. G., Shimony, S., Long, H. W., Neuberg, D. S., Paulo, J. A., Lane, A. A.

10.1101/2023.12.15.571909 — Posted: 2023-12-15

Boosting bactericidal immunity of a recombinant Mycobacterium smegmatis strain via zinc-dependent ribosomal proteins

Singh, S., Kanzin, D., Chavez, S., Saavedra-Avila, N. A., Ng, T., Lukos, R., Mayer, O., Kim, J., Chen, B., Chen, M., Porcelli, S., Jacobs, W. R., Tiwari, S.

10.1101/2023.12.11.571163 — Posted: 2023-12-12

Polygenic prediction of human longevity on the supposition of pervasive pleiotropy

Jabalameli, M. R., Lin, J.-R., Zhang, Q., Wang, Z., Mitra, J., Nguyen, N., Gao, T., Khusidman, M., Atzmon, G., Milman, S., Vijg, J., Barzilai, N., Zhang, Z.

10.1101/2023.12.10.23299795 — Posted: 2023-12-11

Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL

Zhao, Y., Short, N. J., Kantarjian, H. M., Chang, T.-C., Ghate, P. S., Qu, C., Macaron, W., Jain, N., Thakral, B., Phillips, A. H., Khoury, J., Garcia-Manero, G., Zhang, W., Fan, Y., Yang, H., Garris, R. S., Nasr, L. F., Kriwacki, R. W., Roberts, K. G., Konopleva, M., Jabbour, E. J., Mullighan, C. G.

10.1101/2023.12.06.23299616 — Posted: 2023-12-09

Machine-learning-based Structural Analysis of Interactions between Antibodies and Antigens

Zhang, G., Su, Z., Zhang, T., Wu, Y.

10.1101/2023.12.06.570397 — Posted: 2023-12-08

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