Channel: Johns Hopkins University

This collection includes bioRxiv and medRxiv papers from authors at Johns Hopkins University.

5999 Articles

Aberrant Molecular Myelin Architecture in Charcot-Marie-Tooth Disease Type 1A and Hereditary Neuropathy with Liability to Pressure Palsies

Moss, K. R., Arowolo, M. A., Gutierrez, D. R., Hoke, A.

10.1101/2024.05.10.592618 — Posted: 2025-08-15

In vivo bioreactor matures iPSC-CMs for MLP disease modeling

Murphy, S., Cho, G., Limphong, P., Lee, D., Kwon, C.

10.1101/2025.08.11.669708 — Posted: 2025-08-15

Novel Predictive Spatial Biomarker in Non-Small Cell Lung Carcinoma: The Diversity of Niches Unlocking Treatment Sensitivity (DONUTS)

Cottrell, T. R., Roskes, J. S., Fotheringham, M., Cohen, E., Zhang, B., Engle, L. L., Wang, D., Will, E., Sunshine, J. C., Jimenez-Sanchez, D., Zheng, Z., Caushi, J. X., Zhang, J., D'Amiano, N., Stein-Deutsch, J., Uttam, S., Pirie, K., Vlaminck, D., Mataj, M., Fiorante, A., Espinosa, N., Popa, T., Ogurtsova, A., Soto-Diaz, S., Eminizer, M., Tabrisky, S., Jorquera, A., Skidmore, J., Medvedev, D., Chaft, J. E., Brahmer, J. R., Conroy, M., Reuss, J. E., Danilova, L., Ji, H., Forde, P. M., Pardoll, D. M., Smith, K. N., Green, B. F., Szalay, A. S., Taube, J. M.

10.1101/2025.08.13.665980 — Posted: 2025-08-15

Group Response Analysis: Clinically Interpretable Longitudinal Responder Analysis Methods Developed Using FDA Data

DeLorey, I., Bilker, W., Chudnovskaya, D., Conroy, A., McWilliams, T., Miller, C., Argoff, C. E., Barnett, I., Bell, R., Haythornthwaite, J., Gewandter, J., Gilron, I., Katz, N. P., Theken, K. N., Farrar, J. T.

10.1101/2025.08.13.25333581 — Posted: 2025-08-15

Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment

Tolman, N., Li, T., Balasubramanian, R., Li, G., Pfeiffer, R. L., Bupp-Chickering, V., Kelly, R. A., Simon, M., Peregrin, J., Montgomery, C., Jones, B., Stamer, W. D., Qian, J., John, S. W. M.

10.1101/2024.11.01.621152 — Posted: 2025-08-14

A population-scale atlas of blood and tissue in lupus nephritis

Gurajala, S., Sugiarto, N. W., Curtis, M., Eisenhaure, T. M., Arazi, A., Fava, A., Xiao, Q., Mears, J., Rovin, B., Berthier, C. C., Izmirly, P. M., Barnas, J. L., Hoover, P. J., Peters, M., Raychowdhury, R., Horisberger, A., Sakaue, S., Zhao, Y., Furie, R. A., Belmont, H. M., Hildeman, D. A., Woodle, E. S., Dall'Era, M., Putterman, C., Kamen, D. L., McMahon, M. A., Grossman, J., Kalunian, K. C., Hodgin, J. B., Payan-Schober, F., Apruzzese, W., Perlman, H., Cuda, C. M., Wofsy, D., Guthridge, J. M., Anolik, J. H., James, J. A., Accelerating Medicines Partnerships Rheumatoid Arthritis/Systemic Lu

10.1101/2025.08.11.669754 — Posted: 2025-08-14

Survey of benzimidazole resistance in ascarid parasites of poultry

Collins, J., Choo, R., Shaver, A. O., Schaye, E. S., Volpe, T., Nunn, L., Lighty, M. E., Niel, K. R., Frye, E. M., Zamanian, M., Andersen, E. C.

10.1101/2025.08.12.669876 — Posted: 2025-08-13

Paracrine Bone-Derived Senescent Secretome Induces Spatially Patterned ECM and Biomechanical Vulnerability in Human Brain Organoids

Kim, C., Ofria, L. D., Kshirsagar, A., Gomez Flores, E., Kulkarni, S., Liu, A. Y., Kirkland, J. L., Kathuria, A., Tilton, M.

10.1101/2025.08.11.669674 — Posted: 2025-08-13

ClpA- and ClpAP-Catalyzed Unfolding and Translocation are Differentially Coupled to ATP Binding

Islam, L., Banwait, J. K., Lucius, A. L.

10.1101/2025.08.12.669770 — Posted: 2025-08-13

Country-Specific Estimates of Misclassification Rates of Computer-Coded Verbal Autopsy Algorithms

Pramanik, S., Wilson, E. B., Kalter, H. D., Akelo, V., Amouzou, A., Black, R. E., Blau, D., Macicame, I., Muir, J. A., Lee, K. H., Liu, L., Whitney, C. G., Zeger, S., Datta, A.

10.1101/2025.07.02.25329250 — Posted: 2025-08-13

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