Channel: Johns Hopkins University

This collection includes bioRxiv and medRxiv papers from authors at Johns Hopkins University.

6105 Articles

Progression of biological markers in spinocerebellar ataxia type 3: analysis of longitudinal data from the ESMI cohort

Berger, M., Garcia-Moreno, H., Ferreira, M., Hubener-Schmid, J., Schaprian, T., Wegner, P., Elter, T., Teichmann, K. M., Santana, M. M., Grobe-Einsler, M., Onder, D., Koyak, B. S. C., Bernsen, S., Pereira de Almeida, L., Silva, P., Ribeiro, J. A., Cunha, I., Gonzalez-Robles, C., Khan, S., Heslegrave, A., Zetterberg, H., Lima, M., Raposo, M., Ferreira, A. F., Vasconcelos, J., van de Warrenburg, B. P., van Gaalen, J., van Prooije, T. H., de Vries, J., Schols, L., Riess, O., Matthis, S., Timmann, D., Andreas, T., Friedrich, E., Infante, J., Manrique, L., Pelayo, A. L., Reetz, K., Dogan, I., Gulin

10.1101/2025.01.30.25321426 — Posted: 2025-01-31

Bivalent interaction through an intrinsically disordered linker promotes transcription activation complex assembly in Notch signaling

Cook, C., Ramsey, K. M., Barrick, D.

10.1101/2024.11.09.622674 — Posted: 2025-01-30

What has AlphaFold3 learned about antibody and nanobody docking, and what remains unsolved?

Hitawala, F. N., Gray, J. J.

10.1101/2024.09.21.614257 — Posted: 2025-01-29

Study design and the sampling of deleterious rare variants in biobank-scale datasets

Steiner, M. C., Rice, D. P., Biddanda, A., Ianni-Ravn, M. K., Porras, C., Novembre, J.

10.1101/2024.12.02.626424 — Posted: 2025-01-29

mRNA lipid nanoparticle-incorporated nanofiber-hydrogel composite generates a local immunostimulatory niche for cancer immunotherapy

Zhu, Y., Yao, Z.-C., Li, S., Ma, J., Wei, C., Yu, D., Stelzel, J. L., Ni, B. Y. X., Miao, Y., Van Batavia, K., Lu, X., Lin, J., Dai, Y., Kong, J., Shen, R., Goodier, K. D., Liu, X., Cheng, L., Vuong, I., Howard, G. P., Livingston, N. K., Choy, J., Schneck, J. P., Doloff, J. C., Reddy, S. K., Hickey, J. W., Mao, H.-Q.

10.1101/2025.01.27.633179 — Posted: 2025-01-29

Paradoxical mTORC1-Dependent microRNA-mediated Translation Repression in the Nucleus Accumbens of Mice Consuming Alcohol Attenuates Glycolysis

Ehinger, Y., Laguesse, S., Phamluong, K., Salvi, A., Hoisington, Z. W., Soneja, D., Gunasekaran, S., Sei, Y. J., Nakamura, K., Ron, D.

10.1101/2023.11.29.569312 — Posted: 2025-01-28

An anti-amyloidogenic approach to specifically block memory consolidation in mice for therapeutic intervention

Lopez-Garcia, P., McGreevy, K. R., Vaquero, M. E., Ramirez de Mingo, D., Palle, A., Popiel, H. A., Santi, A., Nagai, Y., Trejo, J. L., Carrion-Vazquez, M.

10.1101/2025.01.27.635080 — Posted: 2025-01-28

Cigarette smoke and biological age induce degenerative heterogeneity in retinalpigment epithelium

Singh, K., jin, y., Hu, M., Pallazo, I., Cano,, M., Hoang, T., Bhutto, I., Wang, S., Sinha, D., Blackshaw, S., Qian, J., Handa, J. T.

10.1101/2025.01.27.635096 — Posted: 2025-01-28

Attenuated adenosine mediated immune-dampening increases natural killer cell activity in early age-related macular degeneration

Nair, A. P., Ghosh, S., Babu, V. S., Praveen, M., Xin, Y., Sahu, G. R., Vaidya, T. A., Debnath, J., Raja, K., Gadde, S. G. K., MB, T., Shetty, N., Saxena, A., Shetty, R., Hose, S., Deshpande, V., Chakrabarthy, K., Handa, J. T., Qian, J., Sethu, S., Sinha, D., Ghosh, A.

10.1101/2025.01.22.634301 — Posted: 2025-01-27

Implementation of enhanced 99DOTS for TB treatment supervision in Uganda: An interrupted time series analysis

Crowder, R., Nakasendwa, S., Kityamuwesi, A., Musoke, M., Nannozi, J., Waswa, J., Nakate, A. S., Lamunu, M., Twinamasiko, A., Kunihira Tinka, L., Oyuku, D., Babirye, D., Berger, C., Thompson, R., Turyahabwe, S., Dowdy, D., Katamba, A., Cattamanchi, A., Kiwanuka, N.

10.1101/2024.01.22.24300949 — Posted: 2025-01-27

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