Channel: Johns Hopkins University

This collection includes bioRxiv and medRxiv papers from authors at Johns Hopkins University.

5650 Articles

Local epigenomic state cannot discriminate interacting and non-interacting enhancer-promoter pairs with high accuracy

Xi, W., Beer, M. A.

10.1101/420372 — Posted: 2018-10-25

TADs pair homologous chromosomes to promote interchromosomal gene regulation

Viets, K., Sauria, M., Chernoff, C., Anderson, C., Tran, S., Dove, A., Goyal, R., Voortman, L., Gordus, A., Taylor, J., Johnston, R. J.

10.1101/445627 — Posted: 2018-10-25

Activation of SEDS-PBP cell wall synthases by an essential regulator of bacterial division

Lariviere, P. J., Mahone, C. R., Santiago-Collazo, G., Howell, M., Daitch, A. K., Zeinert, R., Chien, P., Brown, P. J., Goley, E. D.

10.1101/453415 — Posted: 2018-10-25

Comparative validation of breast cancer risk prediction models and projections for future risk stratification

Pal Choudhury, P., Wilcox, A., Brook, M., Zhang, Y., Ahearn, T., Orr, N., Coulson, P., Schoemaker, M. J., Jones, M. E., Gail, M. H., Swerdlow, A. J., Chatterjee, N., Garcia-Closas, M.

10.1101/440347 — Posted: 2018-10-19

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

Vosa, U., Claringbould, A., Westra, H.-J., Bonder, M. J., Deelen, P., Zeng, B., Kirsten, H., Saha, A., Kreuzhuber, R., Kasela, S., Pervjakova, N., Alvaes, I., Fave, M.-J., Agbessi, M., Christiansen, M., Jansen, R., Seppälä, I., Tong, L., Teumer, A., Schramm, K., Hemani, G., Verlouw, J., Yaghootkar, H., Sönmez, R., Andrew, A. A., Kukushkina, V., Kalnapenkis, A., Rüeger, S., Porcu, E., Kronberg-Guzman, J., Kettunen, J., Powell, J., Lee, B., Zhang, F., Arindrarto, W., Beutner, F., BIOS Consortium, , Brugge, H., i2QTL Consortium, , Dmitrieva, J., Elansary, M., Fairfax, B. P., Georges, M., He

10.1101/447367 — Posted: 2018-10-19

Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization

Ward-Caviness, C. K., de Vries, P. S., Wiggins, K. L., Huffman, J. E., Yanek, L. R., Bielak, L. F., Giulianini, F., Guo, X., Kleber, M. E., Kacprowski, T., Gross, S., Petersman, A., Davey Smith, G., Hartwig, F. P., Bowden, J., Hemani, G., Muller-Nuraysid, M., Strauch, K., Koenig, W., Waldenberger, M., Meitinger, T., Pankratz, N., Boerwinkle, E., Tang, W., Fu, Y.-P., Johnson, A. D., Song, C., de Maat, M. P., Uitterlinden, A. G., Franco, O. H., Brody, J. A., McKnight, B., Chen, Y.-D. I., Psaty, B. M., Mathias, R. A., Becker, D. M., Peyser, P. A., Smith, J. A., Bielinski, S. J., Ridker, P. M., Ta

10.1101/448381 — Posted: 2018-10-19

The PAGE Study: How Genetic Diversity Improves Our Understanding of the Architecture of Complex Traits

Wojcik, G., Graff, M., Nishimura, K. K., Tao, R., Haessler, J., Gignoux, C. R., Highland, H. M., Patel, Y. M., Sorokin, E. P., Avery, C. L., Belbin, G. M., Bien, S. A., Cheng, I., Cullina, S., Hodonsky, C. J., Hu, Y., Huckins, L. M., Jeff, J., Justice, A. E., Kocarnik, J. M., Lim, U., Lin, B. M., Lu, Y., Nelson, S. C., Park, S.-S. L., Poisner, H., Preuss, M. H., Richard, M. A., Schurmann, C., Setiawan, V. W., Sockell, A., Vahi, K., Vishnu, A., Verbanck, M., Walker, R., Young, K. L., Zubair, N., Acuna-Alonso, V., Ambite, J. L., Barnes, K. C., Boerwinkle, E., Bottinger, E., Bustamante, C. D., Ca

10.1101/188094 — Posted: 2018-10-17

Unsupervised deconvolution of molecular heterogeneity uncovers novel signatures and glia-neuron ratio

Chen, L., Wang, N., Liu, C., Herrington, D., Clarke, R., Zhang, Z., Wang, Y.

10.1101/435677 — Posted: 2018-10-17

The glutathione cycle shapes synaptic glutamate activity

Sedlak, T., Paul, B. D., Parker, G. M., Hester, L. D., Y, T., Kamiya, A., Snyder, S. H., Sawa, A.

10.1101/325530 — Posted: 2018-10-17

On statistical tests of functional connectome fingerprinting

Wang, Z., Sair, H., Crainiceanu, C., Lindquist, M., Landman, B. A., Resnick, S., Vogelstein, J. T., Caffo, B. S.

10.1101/443556 — Posted: 2018-10-15

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