Channel: Johns Hopkins University

This collection includes bioRxiv and medRxiv papers from authors at Johns Hopkins University.

6775 Articles

Defining and rescuing pathomechanisms of myotubularin and autophagy disruption in a novel human cell model of Charcot-Marie-Tooth Type 4B3

Sharma, M., Mao, X. S., Stumpf, S. C., Wang, L., Chua, J.

10.64898/2026.02.03.703518 — Posted: 2026-02-05

Comparing modelled HIV incidence estimates with empirical HIV incidence observations in high-burden HIV African epidemic settings: systematic review and meta-regression

Stevens, O., Moffa, M., Hunt, J. H., Patel, K., Aytenfisu, T., Akullian, A., Anderson, R. L., Bock, P., Gregson, S., Hayes, R., Iwuji, C., Kasamba, I., Larmarange, J., Lockman, S., Michael, D., Moorhouse, L. R., Mugisha, J., Okongo, E., Petersen, M., Ssempijja, V., Slaymaker, E., Tanser, F., Van Schalwyk, C., Grabowski, M. K., Imai-Eaton, J. W.

10.64898/2026.02.05.26345548 — Posted: 2026-02-05

SCOPE: AI-Assisted Early Detection of Potentially Curable Pancreatic Neoplasms on CT from Local and Global Information

Oviedo, F., Lopez Ramirez, F., Blanco, A., Facciola, J., Kwak, S., Zhao, J. M., Syailendra, E. A., Tixier, F., Dodhia, R., Hruban, R. H., Weeks, W. B., Lavista Ferres, J. M., Chu, L. C., Fishman, E. K.

10.64898/2026.02.04.26345495 — Posted: 2026-02-05

Trans-eQTLs reveal the architecture of human gene regulatory networks

Warmerdam, C. A. R., Westra, H.-J., van der Graaf, A., Bonder, M. J., Deelen, P., van Lieshout, T., Landman, A. J., Jesse, M., Strober, B. J., Boltz, T., Lapinska, S., Nagpal, S., Xie, M., Tay, D., Kirsten, H., Naeem, H., Raghavan, V., Farzeen, A., Teumer, A., Fave, M.-J., Persyn, E., Tokolyi, A., Pool, R., Hottenga, J. J., Rodriguez, R. D., Rivas-Torrubia, M., Hamal Mishra, B., Pierce, B., Tong, L., Wang, Q. S., Hasegawa, T., Chhetri, S. B., Dutta, D., Weiss, S., Dupuis, T., Lyytikäinen, L.-P., Mishra, P. P., Wood, A. R., Burnham, K. L., Wen, J., Cheruiyot, E., Boahen, C. K., Jansen, R., Kro

10.64898/2026.02.04.26343575 — Posted: 2026-02-05

Tissue Injury and Biomaterial Treatment Modulate Tumor Growth and Response to Immunotherapy

Ruta, A., Gray-Gaillard, E. F., Garcia, J. A., Davenport Huyer, L., Mathkour, Y., Cherry, C., Patatanian, M., Mejias, J. C., Maestas, D. R., Krishnan, K., Abraham, P., Wolf, M. T., Smith, K. N., Pardoll, D. M., Elisseeff, J. H.

10.64898/2026.02.02.703323 — Posted: 2026-02-04

Multi-Objective Bayesian Optimization for Data-Efficient Bioprocess Development

Ma, E., Morrissey, J., Duan, S., Lu, Z., Ranpura, S., Arora, S., Dabek, A., Liu, C., Gheorghe, A.-G., Fong, L. K. W., Sani, M., Vrljicak, P., Demirhan, D., Betenbaugh, M.

10.64898/2026.02.02.703372 — Posted: 2026-02-04

APOE ε4 defines a systemic immune endophenotype independent of clinical trajectory in amyotrophic lateral sclerosis

Shvetcov, A., Thomson, S., Kwan, S., Thompson, T. G., Rothstein, J. D., Finney, C. A.

10.64898/2026.02.02.703399 — Posted: 2026-02-04

Effort-Based Decision-Making in Post-Stroke Gait: A Feasibility Study

Sulzer, J., Lorenz, D., Killen, B., Stahl, J., Farrell, A., Osada, S., Waschak, M., Chib, V., Lewek, M.

10.64898/2026.01.28.26344556 — Posted: 2026-02-04

Detection of Endothelial Plaque in Microbial Keratitis using Anterior Segment Optical Coherence Tomography

Ibukun, F., Reddy, K. N., Jain, E., Kuyyadiyil, S., Parmar, G. S., Shekhawat, N. S.

10.64898/2026.02.03.26345494 — Posted: 2026-02-04

Vaccine-Elicited Antibody Responses to Influenza H3N2 Subclade K

Wang, L., Nangle, S., Waller-Pulido, A., McMahan, K., Pereira, J., Chaudhari, J., Barrett, L., Bhowmik, R., Ferrugia, K., Ramsamooj, R., Sordillo, E., Simon, V., van Bakel, H., Mostafa, H., Pekosz, A., Collier, A.-r., Barouch, D.

10.64898/2026.02.02.26345378 — Posted: 2026-02-04

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