Channel: Johns Hopkins University

This collection includes bioRxiv and medRxiv papers from authors at Johns Hopkins University.

5892 Articles

Improving polygenic risk prediction in admixed populations by explicitly modeling ancestral-specific effects via GAUDI

Sun, Q., Rowland, B. T., Chen, J., Mikhaylova, A. V., Avery, C., Peters, U., Lundin, J., Matise, T., Buyske, S., Tao, R., Mathias, R. A., Reiner, A. P., Auer, P. L., Cox, N. J., Kooperberg, C., Thornton, T., Raffield, L. M., Li, Y.

10.1101/2022.10.06.511219 — Posted: 2022-10-08

Pantr2, a trans-acting lncRNA, modulates the differentiation potential of neural progenitors in vivo

Augustin, J. J., Takayangi, S., Hoang, T., Winer, B., Blackshaw, S., Goff, L. A.

10.1101/2022.10.07.511381 — Posted: 2022-10-08

The START domain potentiates HD-ZIPIII transcriptional activity

Husbands, A. Y., Feller, A., Aggarwal, V., Dresden, C. E., Holub, A. S., Ha, T., Timmermans, M. C. P.

10.1101/2022.10.08.511209 — Posted: 2022-10-08

Second-generation dual-channel visible light optical coherence tomography enables wide-field, full-range, and shot-noise limited retinal imaging

Wang, J., Nolen, S., Song, W., Shao, W., Yi, W., Yi, J.

10.1101/2022.10.05.511048 — Posted: 2022-10-07

Inhibition of the proton-activated chloride channel PAC by PIP2

Mihaljevic, L., Zheng, R., Osei-Owusu, J., Lü, W., Qiu, Z.

10.1101/2022.10.06.511171 — Posted: 2022-10-07

Machine Learning Optimization of Candidate Antibodies Yields Highly Diverse Sub-nanomolar Affinity Antibody Libraries

Li, L., Gupta, E., Spaeth, J., Shing, L., Jaimes, R., Caceres, R. S., Bepler, T., Walsh, M. E.

10.1101/2022.10.07.502662 — Posted: 2022-10-07

Long COVID Risk and Pre-COVID Vaccination: An EHR-Based Cohort Study from the RECOVER Program

Brannock, M. D., Chew, R. F., Preiss, A. J., Hadley, E. C., McMurry, J. A., Leese, P. J., Girvin, A. T., Crosskey, M., Zhou, A. G., Moffitt, R. A., Jonsson Funk, M., Pfaff, E., Haendel, M., Chute, C. G., N3C Consortium, , RECOVER Consortium

10.1101/2022.10.06.22280795 — Posted: 2022-10-07

Enhanced mTORC1 signaling and Protein Synthesis in Parkinson Disease Pathogenesis

Khan, M. R., Yin, X., Kang, S.-u., Mitra, J., Wang, H., Brahmachari, S., Karuppagounder, S. S., Kimura, Y., Jhaldiyal, A., Kim, H. H., Gu, H., Chen, R., Redding-Ochoa, J., Troncoso, J., Ha, T., Dawson, V. L., Dawson, T. M.

10.1101/2022.10.03.510455 — Posted: 2022-10-06

Single-cell allele-specific expression analysis reveals dynamic and cell-type-specific regulatory effects

Qi, G., Strober, B. J., Popp, J. M., Ji, H., Battle, A.

10.1101/2022.10.06.511215 — Posted: 2022-10-06

A reference induced pluripotent stem cell line for large-scale collaborative studies

Pantazis, C. B., Yang, A., Lara, E., McDonough, J. A., Blauwendraat, C., Peng, L., Oguro, H., Kanaujiya, J., Zou, J., Sebesta, D., Pratt, G., Cross, E., Blockwick, J., Buxton, P., Kinner-Bibeau, L., Medura, C., Tompkins, C., Hughes, S., Santiana, M., Faghri, F., Nalls, M. A., Vitale, D., Ballard, S., Qi, Y. A., Ramos, D. M., Anderson, K. M., Stadler, J., Narayan, P., Papademetriou, J., Reilly, L., Nelson, M. P., Aggarwal, S., Rosen, L. U., Kirwan, P., Pisupati, V., Coon, S. L., Scholz, S. W., Priebe, T., Öttl, M., Dong, J., Meijer, M., Janssen, L. J. M., Lourenco, V. S., van der Kant, R., Cru

10.1101/2021.12.15.472643 — Posted: 2022-10-05

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