Channel: Johns Hopkins University

This collection includes bioRxiv and medRxiv papers from authors at Johns Hopkins University.

6934 Articles

Study design and the sampling of deleterious rare variants in biobank-scale datasets

Steiner, M. C., Rice, D. P., Biddanda, A., Ianni-Ravn, M. K., Porras, C., Novembre, J.

10.1101/2024.12.02.626424 — Posted: 2025-01-29

mRNA lipid nanoparticle-incorporated nanofiber-hydrogel composite generates a local immunostimulatory niche for cancer immunotherapy

Zhu, Y., Yao, Z.-C., Li, S., Ma, J., Wei, C., Yu, D., Stelzel, J. L., Ni, B. Y. X., Miao, Y., Van Batavia, K., Lu, X., Lin, J., Dai, Y., Kong, J., Shen, R., Goodier, K. D., Liu, X., Cheng, L., Vuong, I., Howard, G. P., Livingston, N. K., Choy, J., Schneck, J. P., Doloff, J. C., Reddy, S. K., Hickey, J. W., Mao, H.-Q.

10.1101/2025.01.27.633179 — Posted: 2025-01-29

Paradoxical mTORC1-Dependent microRNA-mediated Translation Repression in the Nucleus Accumbens of Mice Consuming Alcohol Attenuates Glycolysis

Ehinger, Y., Laguesse, S., Phamluong, K., Salvi, A., Hoisington, Z. W., Soneja, D., Gunasekaran, S., Sei, Y. J., Nakamura, K., Ron, D.

10.1101/2023.11.29.569312 — Posted: 2025-01-28

An anti-amyloidogenic approach to specifically block memory consolidation in mice for therapeutic intervention

Lopez-Garcia, P., McGreevy, K. R., Vaquero, M. E., Ramirez de Mingo, D., Palle, A., Popiel, H. A., Santi, A., Nagai, Y., Trejo, J. L., Carrion-Vazquez, M.

10.1101/2025.01.27.635080 — Posted: 2025-01-28

Cigarette smoke and biological age induce degenerative heterogeneity in retinalpigment epithelium

Singh, K., jin, y., Hu, M., Pallazo, I., Cano,, M., Hoang, T., Bhutto, I., Wang, S., Sinha, D., Blackshaw, S., Qian, J., Handa, J. T.

10.1101/2025.01.27.635096 — Posted: 2025-01-28

Attenuated adenosine mediated immune-dampening increases natural killer cell activity in early age-related macular degeneration

Nair, A. P., Ghosh, S., Babu, V. S., Praveen, M., Xin, Y., Sahu, G. R., Vaidya, T. A., Debnath, J., Raja, K., Gadde, S. G. K., MB, T., Shetty, N., Saxena, A., Shetty, R., Hose, S., Deshpande, V., Chakrabarthy, K., Handa, J. T., Qian, J., Sethu, S., Sinha, D., Ghosh, A.

10.1101/2025.01.22.634301 — Posted: 2025-01-27

Implementation of enhanced 99DOTS for TB treatment supervision in Uganda: An interrupted time series analysis

Crowder, R., Nakasendwa, S., Kityamuwesi, A., Musoke, M., Nannozi, J., Waswa, J., Nakate, A. S., Lamunu, M., Twinamasiko, A., Kunihira Tinka, L., Oyuku, D., Babirye, D., Berger, C., Thompson, R., Turyahabwe, S., Dowdy, D., Katamba, A., Cattamanchi, A., Kiwanuka, N.

10.1101/2024.01.22.24300949 — Posted: 2025-01-27

Improving risk analysis of the environmental drivers of the spillover, emergence/reemergence, and spread of Crimean-Congo haemorrhagic fever virus, Marburg virus, and Middle East respiratory syndrome coronavirus in the East Africa Region

Ajumobi, O., Davis, M., George, C. M., Rosman, L., von DobSchuetz, S., Watson, C., Nuzzo, J.

10.1101/2024.11.07.24316934 — Posted: 2025-01-26

The Heterogeneous Effect of High PEEP strategies on Survival in Acute Respiratory Distress Syndrome: preliminary results of a data-driven analysis of randomized trials

Smit, J. M., Krijthe, J. H., van Bommel, J., Sulemanji, D. S., Villar, J., Suarez-Sipmann, F., Fernandez, R. L., Zampieri, F. G., Maia, I. S., Cavalcanti, A. B., Briel, M., Meade, M. O., Zhou, Q., Brower, R. B., Sinha, P., Bartek, B., Calfee, C. S., Mercat, A., Richard, J.-C., Brochard, L., Serpa Neto, A., Hodgson, C., Baedorf-Kassis, E. N., Talmor, D., Gommers, D., van Genderen, M. E., Reinders, M. J. T., Jonkman, A. H.

10.1101/2025.01.23.25320649 — Posted: 2025-01-26

Retinal optical coherence tomography angiography imaging in population studies

Kashani, A. H., Berendschot, T. T., Bonnin, S., Sobrin, L., Andrade de Jesus, D., Sanchez Brea, L., Collazo Martinez, A., Raman, R., de Vries, V. A., Huang, H., E3 consortium, , Macgillivray, T., Ramdas, W., Webers, C., van Asten, F., Baiser, A., Klaver, C., Breteler, M., Finger, R., Khan, R., Liu, R., Susarla, G., Rizza, A., Li, A., Han, S., Chan, W., Lains, I., Yang, J., Brustoki, K., Khetan, V., Iyengar, S., Benchek, P., Sinnakaruppan, M., Chan, R., van der Heide, F. C.

10.1101/2025.01.22.25320610 — Posted: 2025-01-26

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