Channel: University of Massachusetts Chan Medical School

This collection includes bioRxiv and medRxiv papers from authors at University of Massachusetts Chan Medical School .

1006 Articles

Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST

Sprenger, H.-G., Mittenbuehler, M. J., Sun, Y., Van Vranken, J. G., Schindler, S., Jayaraj, A., Khetarpal, S. A., Vargas-Castillo, A., Puszynska, A. M., Spinelli, J. B., Armani, A., Kunchok, T., Ryback, B., Seo, H.-S., Song, K., Sebastian, L., O Young, C., Braithwaite, C., Dhe-Paganon, S., Burger, N., Mills, E. L., Gygi, S. P., Arthanari, H., Chouchani, E. T., Sabatini, D. M., Spiegelman, B. M.

10.1101/2024.04.10.588849 — Posted: 2024-04-10

Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability

Abbott, K. L., Ali, A., Reinfeld, B. I., Deik, A. A. I., Subudhi, S., Landis, M. D., Hongo, R. A., Young, K. L., Kunchok, T., Nabel, C. S., Crowder, K. D., Kent, J. R., Madariaga, M. L. L., Jain, R. K., Beckermann, K. E., Lewis, C. A., Clish, C. B., Muir, A., Rathmell, W. K., Rathmell, J. C., Vander Heiden, M. G.

10.1101/2023.12.24.573250 — Posted: 2024-04-08

Combinatorial expression of neurexin genes regulates glomerular targeting by olfactory sensory neurons

Park, S. J., Wang, I.-H., Lee, N., Jiang, H.-C., Uemura, T., Futai, K., Kim, D., Macosko, E., Greer, P.

10.1101/2024.04.01.587570 — Posted: 2024-04-02

The mex-3 3' untranslated region is essential for reproduction during temperature stress

Brown, H. E., Varderesian, H. V., Keane, S. A., Ryder, S. P.

10.1101/2024.04.01.587367 — Posted: 2024-04-01

Nucleic Acid Aptamers Protect Against Lead (Pb(II)) Toxicity

Anwar, A., Ramis De Ayreflor Reyes, S., John, A. A., Breiling, E., O'Connor, A. M., Reis, S., Shim, J.-H., Shah, A. A., Srinivasan, J., Farny, N. G.

10.1101/2024.03.28.587288 — Posted: 2024-03-31

Single-cell genomics and regulatory networks for 388 human brains

Emani, P. S., Liu, J. J., Clarke, D., Jensen, M., Warrell, J., Gupta, C., Meng, R., Lee, C. Y., Xu, S., Dursun, C., Lou, S., Chen, Y., Chu, Z., Galeev, T., Hwang, A., Li, Y., Ni, P., Zhou, X., PsychENCODE Consortium, , Bakken, T. E., Bendl, J., Bicks, L., Chatterjee, T., Cheng, L., Cheng, Y., Dai, Y., Duan, Z., Flaherty, M., Fullard, J. F., Gancz, M., Garrido-Martin, D., Gaynor-Gillett, S., Grundman, J., Hawken, N., Henry, E., Hoffman, G. E., Huang, A., Jiang, Y., Jin, T., Jorstad, N. L., Kawaguchi, R., Khullar, S., Liu, J., Liu, J., Liu, S., Ma, S., Margolis, M., Mazariegos, S., Moore, J., M

10.1101/2024.03.18.585576 — Posted: 2024-03-30

Reprogramming of host energy metabolism mediated by the TNF-iNOS-HIF-1alpha axis plays a key role in host resistance to Plasmodium infection

Matteucci, K. C., Assis, P. A., Hirako, I. C., Leite, N. P. S., Pioto, F., OJELABI, O., E. TOLLER-KAWAHISA, J., Costa, D. L., S. Silva, J., Alves-Filho, J. C., Gazzinelli, R.

10.1101/2024.03.26.586751 — Posted: 2024-03-29

Traumatic injury causes selective degeneration and TDP-43 mislocalization in human iPSC-derived C9orf72-associated ALS/FTD motor neurons

Martin, E. J., Santacruz, C., Mitevska, A., Jones, I. E., Krishnan, G., Gao, F.-B., Finan, J. D., Kiskinis, E.

10.1101/2024.03.21.586073 — Posted: 2024-03-26

The oligogenic structure of amyotrophic lateral sclerosis has genetic testing, counselling, and therapeutic implications

Iacoangeli, A., Dilliott, A. A., Al Khleifat, A., Andersen, P. M., Basak, N. A., Cooper-Knock, J., Corcia, P., de Carvalho, M., Drory, V., Glass, J. D., Gotkine, M., Lerner, Y. M., Hardiman, O., Landers, J., McLaughlin, R., Mora Pardina, J. S., Morrison, K. E., Pinto, S., Povedano, M., Shaw, C. E., Shaw, P. J., Silani, V., Ticozzi, N., van Damme, P., den Berg, L., Vourc'h, P., Weber, M., Veldink, J., Project MinE ALS Sequencing, , Dobson, R., Rouleau, G., Al-Chalabi, A., Farhan, S.

10.1101/2024.03.21.24304693 — Posted: 2024-03-26

Calcineurin promotes adaptation to chronic stress through two distinct mechanisms

Flynn, M. J., Harper, N. W., Li, R., Zhu, L. J., Lee, M. J., Benanti, J. A.

10.1101/2024.03.19.585797 — Posted: 2024-03-20

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