Channel: University of California, San Diego

This collection includes bioRxiv and medRxiv papers from authors at University of California, San Diego.

4705 Articles

3D organoids containing endothelial and neural cells generation by serial inductions of differentiation on human iPSC-derived embryoid bodies

Wang, T., Bagnell, A., McDonald, V., Gastfriend, B. D., Steiner, J. P., Elkahloun, A. G., Johnson, K., Langston, R. G., Cookson, M. R., Nath, A.

10.1101/2025.05.20.653559 — Posted: 2025-05-21

Joint linear modeling of transcriptomics and proteomics reveals molecular coordination in cancer metastasis

Sharma, R., Meimetis, N., Begzati, A., Nagar, S. D., Kellman, B., Baghdassarian, H. M.

10.1101/2025.02.15.638428 — Posted: 2025-05-20

Single-Cell Epigenomics Uncovers Heterochromatin Instability and Transcription Factor Dysfunction during Mouse Brain Aging

Amaral, M. L., Mamde, S., Miller, M., Hou, X., Arzavala, J., Osteen, J., Walker Smoot, E., Yang, Q., Eisner, E., Zeng, Q., Baez-Becerra, C. T., Olness, J., Kern, J. C., Rink, J., Johnson, N., Barcoma, A., Cho, S., Cao, S., Emerson, N., Lee, J., Willier, J., Loe, T., Jiao, H., Zu, S., Zhu, Q., Preissl, S., Wang, A., Ecker, J., Behrens, M. M., Ren, B.

10.1101/2025.04.21.649585 — Posted: 2025-05-20

Break-induced replication is activated to repair R-loop-associated double-strand breaks in SETX-deficient cells

Wu, T., Li, Y., Shi, L. Z., Wu, X.

10.1101/2024.06.29.601361 — Posted: 2025-05-19

Reconstructing the three-dimensional architecture of extrachromosomal DNA with ec3D

Chowdhury, B., Zhu, K., Li, C., Luebeck, J., Chapman, O. S., Kraft, K., Zhang, S., Chavez, L., Henssen, A. G., Mischel, P. S., Chang, H., Bafna, V.

10.1101/2025.02.01.636064 — Posted: 2025-05-19

Redirecting cytomegalovirus immunity against pancreas cancer for immunotherapy

Marrocco, R., Patel, J., Medari, R., Salu, P., Lucero-Meza, E., Brunel, S., Martsinkovskiy, A., Sun, S., Gulay, K., Jaljuli, M., Mose, E., Lowy, A., Benedict, C. A., Hurtado de Mendoza, T.

10.1101/2025.05.15.654308 — Posted: 2025-05-19

1-Deoxysphingolipids dysregulate membrane properties and cargo trafficking in the early secretory pathway

Tsai, Y.-T., Frederic-Lipp, N., Varma, R., Seidel, O., Laguerre, A., Solorio-Kirpichyan, K., Wong, A., Brea, R. J., McGregor, G. H., Cordes, T., Devaraj, N. K., Kuerschner, L., Neal, S. E., Metallo, C., Budin, I.

10.1101/2025.05.13.652513 — Posted: 2025-05-18

A cold-inducible phospholipid--protein interaction in brown fat mitochondria optimizes thermogenic capacity

Shimanaka, Y., Tol, M. J., Rocha-Roa, C., Jellinek, M. J., Cui, L., Bender, A., Bedard, A. H., Milner, M. G., Melillo, B., Shoucri, B. M., Wong, A., Williams, K. J., Stiles, L., Shum, M., Weston, T. A., Cohn, W., Whitelegge, J. P., Budin, I., Bertholet, A. M., Cravatt, B. F., Young, S. G., Houten, S. M., Argmann, C., Ford, D. A., Liesa, M., Shirihai, O. S., Vanni, S., Tontonoz, P.

10.1101/2025.05.15.654206 — Posted: 2025-05-18

VADEr: Vision Transformer-Inspired Framework for Polygenic Risk Reveals Underlying Genetic Heterogeneity in Prostate Cancer

Talwar, J. V., Klie, A., Pagadala, M. S., Pasternak, G., Rose, B., Seibert, T. M., Gymrek, M., Carter, H.

10.1101/2025.05.16.25327672 — Posted: 2025-05-18

Inhibition of phosphodiesterase 4B as a novel therapeutic strategy for the treatment of refractory epilepsy

Kinch, C. D., Kesler, M., Dogra, D. D., Morin, K., Ibhazehiebo, K., Noschang, C. G., Rho, J. M., Kurrasch, D.

10.1101/2025.05.13.653835 — Posted: 2025-05-17

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