Channel: University of California, San Diego

This collection includes bioRxiv and medRxiv papers from authors at University of California, San Diego.

4658 Articles

The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection

Sandoval, D. R., Mandel Clausen, T., Nora, C., Magida, J. A., Cribbs, A. P., Denardo, A., Clark, A. E., Garretson, A. F., Coker, J. K. C., Narayanan, A., Majowicz, S. A., Philpott, M., Johansson, C., Dunford, J. E., Spliid, C. B., Golden, G. J., Payne, N. C., Tye, M. A., Nowell, C. J., Griffis, E. R., Piermatteo, A., Grunddal, K. V., Alle, T., Hauser, B. M., Feldman, J., Caradonna, T. M., Pu, Y., Yin, X., McVicar, R. N., Kwong, E. M., Tsimikas, S., Schmidt, A. G., Ballatore, C., Zengler, K., Chanda, S. K., Weiss, R. J., Downes, M., Evans, R. M., Croker, B. A., Leibel, S. L., Jose, J., Mazitsch

10.1101/2021.03.22.436522 — Posted: 2021-03-26

An empirical pipeline for personalized diagnosis of Lafora disease mutations

Brewer, M. K., Machio-Castello, M., Viana, R., Wayne, J. L., Kuchtova, A., Simmons, Z. R., Sternbach, S., Li, S., Garcia-Gimeno, M. A., Serratosa, J., Sanz, P., Vander Kooi, C. W., Gentry, M. S.

10.1101/2021.03.26.437206 — Posted: 2021-03-26

Genotype-phenotype correlations in SCN8A-related disorders reveal prognostic and therapeutic implications

Johannesen, K. M., Liu, Y., Tronhjem, C. E., Koko, M., Sonnenberg, L., Schubert, J., Fenger, C. D., Eltokhi, A., Rannap, M., Koch, N. A., Lauxmann, S., Krüger, J., Kegele, J., Canafoglia, L., Franceschetti, S., Mayer, T., Rebstock, J., Zacher, P., Ruf, S., Alber, M., Sterbova, K., Lassuthová, P., Vlckova, M., Lemke, J. R., Krey, I., Heine, C., Wieczorek, D., Kroell-Seger, J., Lund, C., Klein, K. M., Au, P. B., Rho, J. M., Ho, A. W., Masnada, S., Veggiotti, P., Giordano, L., Accorsi, P., Hoi-Hansen, C., Striano, P., Zara, F., Verhelst, H., Verhoeven, J. S., van der Zwaag, B., Harder, A.

10.1101/2021.03.22.21253711 — Posted: 2021-03-26

Saliva testing as a means to monitor therapeutic lithium levels in patients with psychiatric disorders: identification of clinical and environmental covariates, and their incorporation into a prediction model

Parkin, G. M., McCarthy, M. J., Thein, S. H., Piccerillo, H. L., Warikoo, N., Granger, D. A., Thomas, E. A.

10.1101/2021.03.23.21253841 — Posted: 2021-03-26

Parasitic nematode fatty acid- and retinol-binding proteins compromise host immunity by interfering with host lipid signaling pathways

Parks, S., Nguyen, C., Nasrolahi, S., Juncaj, D., Lu, D., Ramaswamy, R., Dhillon, H., Buchman, A., Akbari, O. S., Yamanaka, N., Boulanger, M. J., Dillman, A. R.

10.1101/2021.03.25.436866 — Posted: 2021-03-25

Gene-experience correlation during cognitive development: Evidence from the Adolescent Brain Cognitive Development (ABCD) StudySM

Loughnan, R., Palmer, C. E., Thompson, W. K., Dale, A. M., Jernigan, T. L., Fan, C. C.

10.1101/637512 — Posted: 2021-03-25

Independent Markov Decomposition: Towards modeling kinetics of biomolecular complexes

Hempel, T., del Razo, M. J., Lee, C. T., Taylor, B. C., Amaro, R. E., Noe, F.

10.1101/2021.03.24.436806 — Posted: 2021-03-25

Smoking methylation marks for prediction of urothelial cancer risk

Yu, C., Jordahl, K. M., Bassett, J. K., Joo, J. E., Wong, E. M., Brinkman, M., Schmidt, D. F., Bolton, D. M., Makalic, E., Brasky, T. M., Shadyab, A. H., Tinker, L., Longano, A., Hopper, J. L., English, D. R., Milne, R. L., Bhatti, P., Southey, M. C., Giles, G. G., Dugue, P.-A.

10.1101/2021.03.16.21253681 — Posted: 2021-03-24

Nicotine-mediated recruitment of GABAergic neurons to a dopaminergic phenotype attenuates motor deficits in alpha-synuclein Parkinson's model.

Lai, I.-C., Romoli, B., Keisler, M., Manfredsson, F., Powell, S. B., Dulcis, D.

10.1101/2021.02.15.431290 — Posted: 2021-03-23

Genes identified in rodent studies of alcohol intake are enriched for heritability of human substance use

Huggett, S. B., Johnson, E. C., Hatoum, A. S., Lai, D., Bubier, J. A., Chesler, E. C., Agrawal, A. A., Palmer, A., Edenberg, H. J., Palmer, R. H. C.

10.1101/2021.03.22.436527 — Posted: 2021-03-23

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