Channel: University of California, San Diego

This collection includes bioRxiv and medRxiv papers from authors at University of California, San Diego.

4599 Articles

T cell responses towards PINK1 and α-synuclein are elevated in prodromal Parkinson's disease

Johansson, E., Freuchet, A., Williams, G. P., Michealis, T., Frazier, A., Litvan, I., Goldman, J. G., Alcalay, R. N., Standaert, D. G., Amara, A. W., Stover, N., Fon, E. A., Postuma, R. B., Sidney, J., Sulzer, D., Lindestam Arlehamn, C. S., Sette, A.

10.1101/2025.04.21.649871 — Posted: 2025-04-24

A Lipid Prodrug Strategy Enhances Targeted Protein Degrader CNS Pharmacokinetics

Leconte, G., Gadbois, G. E., Sepulveda, Y., Schwarz, A., Chang, E., Suhandynata, R. T., Momper, J. D., Ferguson, F.

10.1101/2025.04.18.649560 — Posted: 2025-04-24

WITHDRAWN: SARS-CoV-2 invades cognitive centers of the brain and induces Alzheimer's-like neuropathology

Shen, W.-B., Elahi, M., Logue, J., Yang, P., Baracco, L., Reece, E. A., Wang, B., Li, L., Blanchard, T., Han, Z., Frieman, M., Rissman, R. A., Yang, P.

10.1101/2022.01.31.478476 — Posted: 2025-04-23

Synaptic Spine Head Morphodynamics from Graph Grammar Rules for Actin Dynamics

Hur, M., Bartol, T., Rangamani, P., Sejnowski, T., Mjolsness, E.

10.1101/2025.04.18.649558 — Posted: 2025-04-21

Cell-type-specific transposable element demethylation and TAD remodeling in the aging mouse brain

Zeng, Q., Tian, W., Klein, A., Bartlett, A., Liu, H., Nery, J. R., Castanon, R. G., Osteen, J., Johnson, N., Wang, W., Ding, W., Chen, H., Altshul, J., Kenworthy, M., Valadon, C., Owens, W., Wu, Z., Amaral, M. L., Song, Y., Baez-Becerra, C. T., Cho, S., Chen, C., Willier, J., Cao, S., Rink, J., Lee, J., Barcoma, A., Arzavala, J., Emerson, N., Lu, Y. R., Ren, B., Behrens, M. M., Ecker, J. R.

10.1101/2025.04.21.648266 — Posted: 2025-04-21

Human CCR4 deadenylase homolog Angel1 is a Non-Stop mRNA Decay factor

Nicholson-Shaw, T., Dowdle, M. E., Ajaj, Y., Perelis, M., Fulzele, A., Yeo, G. W., Bennett, E. J., Lykke-Anderson, J.

10.1101/2022.04.28.489582 — Posted: 2025-04-21

The 4th GPCR Dock: assessment of blind predictions for GPCR-ligand complexes in the era of AlphaFold

Chitsazi, R., Wu, Y., GPCR Dock 2021 participants, , Stevens, R. C., Zhao, S., Kufareva, I.

10.1101/2025.04.18.647407 — Posted: 2025-04-20

Higher Ventilation Rate is Associated with Increased Return of Spontaneous Circulation in In-Hospital Cardiac Arrest Patients with Advanced Airways

Jaffe, I. S., Ren, Y., Tran, L., Yuriditsky, E., Gonzales, A. M., Patel, J. K., Shahnawaz, S., Howoritz, J., Bloom, B. M., Pradhan, D., Kulstad, E., Jarman, H., Tong, N., Thomas, M., Chan, L., Page, V., Deakin, C. D., Perkins, G. D., Yu, C., Parnia, S.

10.1101/2025.04.17.25326045 — Posted: 2025-04-20

Profiling the human luminal small intestinal microbiome using a novel ingestible medical device

Tronel, A., Roger-Margueritat, M., Plazy, C., Biennier, S., Craspay, A., Mohanty, I., Cools-Portier, S., Laiola, M., Roeselers, G., Mathieu, N., Hupe, M., Dorrestein, P. C., Alcaraz, J. P., Martin, D., CINQUIN, P., Silvent, A. S., Giai, J., Proust, M., Soranzo, T., Buelow, E., Le Gouellec, A.

10.1101/2025.04.18.25326056 — Posted: 2025-04-20

Fast and accessible morphology-free functional fluorescence imaging analysis

Estrada Berlanga, A. A., Kang, G., Kwok, A., Broggini, T., Lawlor, J., Kuchibhotla, K., Kleninfeld, D., Mishne, G., Charles, A.

10.1101/2025.04.15.648462 — Posted: 2025-04-20

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