Channel: Vanderbilt University

This collection includes bioRxiv and medRxiv papers from authors at Vanderbilt University.

3069 Articles

Genetic drivers and clinical consequences of mosaic chromosomal alterations in 1 million individuals

Zhao, K., Pershad, Y., Poisner, H. M., Ma, X., Quade, K., Vlasschaert, C., Mack, T., Khankari, N. K., von Beck, K., Brogan, J., Kishtagari, A., Corty, R., Li, Y., Xu, Y., Reiner, A. P., Scheet, P., Auer, P., Bick, A. G.

10.1101/2025.03.05.25323443 — Posted: 2025-03-06

A Broad Survey and Functional Analysis of Immunoglobulin Loci Variation in Rhesus Macaques

Peres, A., Upadhyay, A. A., Klein, V. H., Saha, S., Rodriguez, O. L., Vanwinkle, Z. M., Karunakaran, K., Metz, A., Lauer, W., Lin, M. C., Melton, T., Granholm, L., Polak, P., Peterson, S. M., Peterson, E. J., Raju, N., Shields, K., Schultze, S., Ton, T., Ericsen, A., Lapp, S. A., Villinger, F. J., Ohlin, M., Cottrell, C., Amara, R. R., Derdeyn, C. A., Crotty, S., Schief, W., Karlsson Hedestam, G. B., Smith, M., Lees, W., Watson, C. T., Yaari, G., Bosinger, S. E.

10.1101/2025.01.07.631319 — Posted: 2025-03-06

Dynamic responses to rejection in the transplanted human heart revealed through spatial transcriptomics

Amancherla, K., Taravella Oill, A. M., Bledsoe, X., Williams, A. L., Chow, N., Zhao, S., Sheng, Q., Bearl, D. W., Hoffman, R. D., Menachem, J. N., Siddiqi, H. K., Brinkley, D. M., Mee, E. D., Hadad, N., Agrawal, V., Schmeckpepper, J., Rali, A. S., Tsai, S., Farber-Eger, E. H., Wells, Q. S., Freedman, J. E., Tucker, N. R., Schlendorf, K. H., Gamazon, E. R., Shah, R. V., Banovich, N.

10.1101/2025.02.28.640852 — Posted: 2025-03-06

irAE-GPT: Leveraging large language models to identify immune-related adverse events in electronic health records and clinical trial datasets

Bejan, C. A., Wang, M., Venkateswaran, S., Bergmann, E. A., Hiles, L., Xu, Y., Chandler, G. S., Brondfield, S., Silverstein, J., Wright, F., de Dios, K., Kim, D., Mukherjee, E., Krantz, M. S., Yao, L., Johnson, D. B., Phillips, E. J., Balko, J. M., Mohindra, R., Quandt, Z.

10.1101/2025.03.05.25323445 — Posted: 2025-03-06

An Integrative Multi-Omics Random Forest Framework for Robust Biomarker Discovery

Zhang, W., Huang, H., Wang, L., Lehmann, B. D., Chen, S. X.

10.1101/2025.03.05.641533 — Posted: 2025-03-06

Lyme disease increases risk for multiple gynecological conditions

Hansen Colburn, P. S., Blacker, G., Galloway, S., Feng, Q., Padmanabham, P. S., Pisani, G., Lee, B. T., Loeser, G., Perez, M. W., Liu, K., Kuan, J., von Saltza, E., Strausz, S., Mattei, L., Nahass, G. R., Kitjasateanphun, A., Potula, H.-H. S., Shoham, M. A., Finngen, , Mascetti, V. L., Gars, E., Ollila, H. M., Bruner-Tran, K. L., Weissman, I. L., You, S., Pollack, B., Griffith, L., Sinnott-Armstrong, N., Tal, M. C.

10.1101/2025.03.03.25323258 — Posted: 2025-03-06

Gene discovery and pleiotropic architecture of Chronic Pain in a Genome-wide Association Study of >1.2 million Individuals

Toikumo, S., Davis, C. N., Jinwala, Z., Khan, Y., Jennings, M., Davis, L., Sanchez-Roige, S., Kember, R. L., Kranzler, H.

10.1101/2025.02.28.25323112 — Posted: 2025-03-05

Correlative In Situ Cryo-ET Reveals Cellular and Viral Remodeling Associated with Selective HIV-1 Core Nuclear Import

Hou, Z., Shen, Y., Fronik, S., Shen, J., Shi, J., Xu, J., Chen, L., Hardenbrook, N., Thompson, C., Neumann, S., Engelman, A. N., Aiken, C., zhang, p.

10.1101/2025.03.04.641496 — Posted: 2025-03-04

Load-based divergence in the dynamic allostery of two TCRs recognizing the same pMHC

Chang-Gonzalez, A. C., Akitsu, A., Mallis, R. J., Lang, M. J., Reinherz, E. L., Hwang, W.

10.1101/2024.10.16.618634 — Posted: 2025-03-03

Overlap of high-risk individuals predicted by family history, genetic and non-genetic breast cancer risk prediction models: An analysis of 180,398 women across European and Asian ancestry populations

Ho, P. J., Loo, C. K. Y., Goh, M. H., Abubakar, M., Ahearn, T. U., Andrulis, I. L., Antonenkova, N. N., Aronson, K. J., Augustinsson, A., Behrens, S., Bodelon, C., Bogdanova, N. V., Bolla, M. K., Brantley, K., Brenner, H., Byers, H., Camp, N. J., Castelao, J. E., Cessna, M. H., Chang-Claude, J., Chanock, S. J., Chenevix-Trench, G., Choi, J.-Y., Colonna, S. V., Czene, K., Daly, M. B., Derouane, F., Dork, T., Eliassen, A. H., Engel, C., Eriksson, M., Evans, D. G., Fletcher, O., Fritschi, L., Gago-Dominguez, M., Genkinger, J. M., Geurts-Giele, W. R. R., Glendon, G., Hall, P., Hamann, U., Ho, C. Y

10.1101/2025.02.27.25323002 — Posted: 2025-03-03

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