Channel: Vanderbilt University

This collection includes bioRxiv and medRxiv papers from authors at Vanderbilt University.

3069 Articles

Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder

Strom, N. I., Gerring, Z. F., Galimberti, M., Yu, D., Halvorsen, M. W., Abdellaoui, A., Rodriguez-Fontenla, C., Sealock, J. M., Bigdeli, T., Coleman, J. R. I., Mahjani, B., Thorp, J. G., Bey, K., Burton, C. L., Luykx, J. J., Zai, G., Alemany, S., Andre, C., Askland, K. D., Banaj, N., Barlassina, C., Becker Nissen, J., Bienvenu, O. J., Black, D., Bloch, M. H., Bäckman, J., Borte, S., Bosch, R., Breen, M., Brennan, B. P., Brentani, H., Buxbaum, J. D., Bybjerg-Grauholm, J., Byrne, E. M., Cabana-Dominguez, J., Camarena, B., Camarena, A., Cappi, C., Carracedo, A., Casas, M., Cavallini, M. C., Ciul

10.1101/2024.03.13.24304161 — Posted: 2025-04-08

Transmembrane Serine Protease TMPRSS11B promotes an acidified tumor microenvironment and immune suppression in lung squamous cell carcinoma

Sunil, H. S., Clemenceau, J., Barnfather, I., Nakkireddy, S. R., Grichuk, A., Izzo, L. T., Evers, B. M., Thomas, L., Subramaniyan, I., Li, L., Putnam, W. T., Zhu, J., Updegraff, B., Minna, J. D., DeBerardinis, R. J., Gao, J., Hwang, T. H., Oliver, T. G., O'Donnell, K. A.

10.1101/2025.04.01.646727 — Posted: 2025-04-03

Current Limitations of Electronic Health Record Systems in Supporting Pragmatic Clinical Trials: Insights from the eMERGE Consortium

Wagholikar, K. B., Pacheco, J. A., Gordon, A. S., Khan, A., Khales, B. N., Benoit, B., Kerman, B. J., Weng, C., Ta, C., Prows, C. A., Johnson, R., Roden, D. M., Crosslin, D., McNally, E. M., Karlson, E. W., Mentch, F., Jarvik, G. P., Wiesner, G. L., Hakonarson, H., Cimino, J. J., Thayer, J. G., Smoller, J. W., Linder, J. E., Connolly, J., Peterson, J. F., Cortopassi, J., Kiryluk, K., Hamed, M., Maradik, M., Puckelwartz, M. J., Naderian, M., Walton, N., Limdi, N., Maripuri, D. P., Walunas, T., Gainer, V., Luo, Y., Liu, C., Kenny, E. E., Espinoza, A., Rowley, R., Wei, W.-Q., Murphy, S.

10.1101/2025.04.01.25325049 — Posted: 2025-04-03

Development and validation of a harmonized memory score for multicenter Alzheimer's disease and related dementia research

Sanderson-Cimino, M., Gross, A. L., Gaynor, L. S., Paolillo, E. W., Saloner, R., Albert, M. S., Apostolova, L. G., Boersema, B., Boxer, A. L., Boeve, B. F., Casaletto, K. B., Hallgarth, S. R., Diaz, V. E., Clark, L. R., Maillard, P., Eloyan, A., Tomaszewski Farias, S., Gonzales, M. M., Hammers, D. B., La Joie, R., Cobigo, Y., Wolf, A., Hampstead, B. M., Mechanic-Hamilton, D., Miller, B. L., Rabinovici, G. D., Ringman, J. M., Rosen, H. J., Ryman, S. G., Prestopnik, J. L., Salmon, D. P., Smith, G. E., DeCarli, C., Rajan, K. B., Jin, L.-W., Hinman, J., Johnson, D. K., Harvey, D., Fornage, M., Kra

10.1101/2025.03.31.25324964 — Posted: 2025-04-03

Pcdh20 is a POU2F3 target gene required for proper tuft cell microvillus formation

Ankenbauer, K. E., Yang, Y., Chung, C.-Y., Andrade, L. R., Weiser Novak, S., Jarvis, B., Ali Hanel, W. H., Liu, J., Sarkisian, V., Dani, N., Krystofiak, E., Hu, G., Ebrahim, S., Kachar, B., Gong, Q., Wahl, G., Manor, U., Lau, K., DelGiorno, K. E.

10.1101/2025.03.18.644042 — Posted: 2025-04-02

Substrate stiffness and shear stress collectively regulate the inflammatory phenotype in cultured human brain microvascular endothelial cells

Yates, A., Murray, H., Kjar, A., Chavarria, D., Masters, H., Kim, H., Ligocki, A., Jefferson, A., Lippmann, E.

10.1101/2025.03.31.646228 — Posted: 2025-04-02

Functional profiling of KCNE1 variants informs population carrier frequency of Jervell and Lange-Nielsen syndrome type 2

Vanoye, C. G., Desai, R. R., John, J., Hoffman, S., Fink, N., Zhang, Y., Venkatesh, O., Roe, J., Adusumilli, S., Jairam, N., Sanders, C., Gordon, A., George, A. L.

10.1101/2025.03.28.646046 — Posted: 2025-04-01

Photoperiodic Regulation of SK Channels in Dorsal Raphe Serotonin Neurons

Giannoni Guzman, M. A., Zepeda, J. C., Kamitakahara, A., Magalong, V., Levitt, P., Grueter, B., McMahon, D. G.

10.1101/2025.03.29.646123 — Posted: 2025-04-01

Contrastive Learning Enables Epitope Overlap Predictions for Targeted Antibody Discovery

Holt, C. M., Janke, A. K., Amlashi, P. B., Marinov, T. M., Georgiev, I. S.

10.1101/2025.02.25.640114 — Posted: 2025-04-01

Polygenic Associations between Motor Behaviour, Neuromotor Traits, and Active Music Engagement in Four Cohorts

Henechowicz, T. L., Coleman, P. L., Gustavson, D. E., Mekki, Y. N., Nayak, S., Nitin, R., Scartozzi, A. C., Tio, E. S., van Klei, R., Felsky, D., Thaut, M. H., Gordon, R. L.

10.1101/2025.03.27.645667 — Posted: 2025-03-30

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