Channel: Vanderbilt University

This collection includes bioRxiv and medRxiv papers from authors at Vanderbilt University.

3072 Articles

The C99 domain of the amyloid precursor protein is a disordered membrane phase-preferring protein

Capone, R. F., Tiwari, A., Hadziselimovic, A., Peskova, Y., Hutchinson, J. M., Sanders, C. R., Kenworthy, A. K.

10.1101/2020.11.25.397893 — Posted: 2020-11-25

Actionable druggable genome-wide Mendelian randomization identifies repurposingopportunities for COVID-19

Gaziano, L., Giambartolomei, C., Pereira, A. C., Gaulton, A., Posner, D. C., Swanson, S. A., Ho, Y. L., Iyengar, S. K., Kosik, N. M., Vujkovic, M., Gagnon, D. R., Bento, A. P., Beltrao, P., Barrio Hernandez, I., Ronnblom, L., Hagberg, N., Lundtoft, C., Langenberg, C., Pietzner, M., Valentine, D., Allara, E., Surendran, P., Burgess, S., Zhao, J. H., Peters, J. E., Prins, B. P., Danesh, J., Devineni, P., Shi, Y., Lynch, K. E., DuVall, S. L., Garcon, H., Thomann, L., Zhou, J. J., Gorman, B. R., Huffman, J. E., O'Donnell, C. J., Tsao, P. S., Beckham, J. C., Pyarajan, S., Muralidhar, S., Huang, G.

10.1101/2020.11.19.20234120 — Posted: 2020-11-23

Largest GWAS (N=1,126,563) of Alzheimer's Disease Implicates Microglia and Immune Cells

Wightman, D. P., Jansen, I. E., Savage, J. E., Shadrin, A. A., Bahrami, S., Rongve, A., Borte, S., Winsvold, B. S., Drange, O. K., Martinsen, A. E., Skogholt, A. H., Willer, C., Brathen, G., Bosnes, I., Nielsen, J. B., Fritsche, L., Thomas, L. F., Pedersen, L. M., Gabrielsen, M. E., Johnsen, M. B., Meisingset, T. W., Zhou, W., Proitsi, P., Hodges, A., Dobson, R., Velayudhan, L., 23andMe Research Team, , Sealock, J. M., Davis, L. K., Pedersen, N. L., Reynolds, C. A., Karlsson, I. K., Magnusson, S., Stefansson, H., Thordardottir, S., Jonsson, P. V., Snaedal, J., Zettergren, A., Skoog, I., Kern

10.1101/2020.11.20.20235275 — Posted: 2020-11-23

IBEX: A versatile multi-plex optical imaging approach for deep phenotyping and spatial analysis of cells in complex tissues

Radtke, A. J., Kandov, E., Lowekamp, B., Speranza, E., Chu, C. J., Gola, A., Thakur, N., Shih, R., Yao, L., Yaniv, Z. R., Beuschel, R. T., Kabat, J., Croteau, J., Davis, J., Hernandez, J. M., Germain, R. N.

10.1101/2020.11.20.390690 — Posted: 2020-11-21

Rooting the animal tree of life

Li, Y., Shen, X.-X., Evans, B., Dunn, C. W., Rokas, A.

10.1101/2020.10.27.357798 — Posted: 2020-11-20

Disentangling genetic feature selection and aggregation in transcriptome-wide association studies

Cao, C., Kwok, D., Li, Q., He, J., Guo, X., Zhang, Q., Long, Q.

10.1101/2020.11.19.390617 — Posted: 2020-11-20

Polygenic transcriptome risk scores improve portability of polygenic risk scores across ancestries

Liang, Y., Pividori, M., Manichaikul, A., Palmer, A. A., Cox, N. J., Wheeler, H. E., Im, H. K.

10.1101/2020.11.12.373647 — Posted: 2020-11-18

Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the unfolded protein response (UPR) in models of neurodegeneration

Vidal, R. L., Sepulveda, D., Troncoso-Escudero, P., Garcia-Huerta, P., Gonzalez, C., Plate, L., Jerez, C., Canovas, J., Rivera, C., Castillo, V., Cisternas, M., Leal, S., Martinez, A., Grandjean, J., Lashuel, H., Martin, A. J. M., Latapiat, V., Matus, S., Sardi, S. P., Wiseman, L., Hetz, C.

10.1101/2020.11.17.387480 — Posted: 2020-11-18

Rare Non-coding Variation Identified by Large Scale Whole Genome Sequencing Reveals Unexplained Heritability of Type 2 Diabetes: Trans-Omics for Precision Medicine (TOPMed) Program

Wessel, J., Majarian, T. D., Highland, H. M., Raghavan, S., Szeto, M. D., Hasbani, N. R., de Vries, P. S., Brody, J. A., Sarnowski, C., DiCorpo, D., Yin, X., Hidalgo, B., Guo, X., Perry, J., O'Connell, J. R., Lent, S., Montasser, M. E., Cade, B. E., Jain, D., Wang, H., Wu, P., Bonas-Guarch, S., D'Oliveira Albanus, R., Leong, A., Miguel-Escalada, I., Varshney, A., NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, , TOPMed Anthropometry, , DIAMANTE, , Kinney, G. L., Yanek, L. R., Lange, L., Almeida, M., Peralta, J., Aslibekyan, S., Baldridge, A. S., Bertoni, A. G., Bielak, L. F.

10.1101/2020.11.13.20221812 — Posted: 2020-11-16

Prevalence of IgG antibodies against the severe acute respiratory syndrome coronavirus-2 among healthcare workers in Tennessee during May and June, 2020

Rebeiro, P. F., Levinson, K. J., Jolly, L., Kassens, E., Dizikes, G. J., Steece, R. S., Metzger, D. C., Loos, M., Buchheit, R., Duncan, L. D., Rolando, L. A., Schmitz, J., Hart, H. A., Aronoff, D. M., Tennessee COVID-19 Serology Study Team

10.1101/2020.11.12.20230912 — Posted: 2020-11-16

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