Channel: Vanderbilt University

This collection includes bioRxiv and medRxiv papers from authors at Vanderbilt University.

2789 Articles

No evidence for whole-chromosome dosage compensation or global transcriptomic expression differences in spontaneously-aneuploid mutation accumulation lines of Saccharomyces cerevisiae

McQueary, H. C., Behringer, M. G., Chamberlin, J., Tsfoni, A., Canas, A., Demario, S., Johnson, B. S., Hall, D. W.

10.1101/2020.12.01.404830 — Posted: 2020-12-02

Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor

Godsel, L. M., Roth-Carter, Q. R., Koetsier, J. L., Tsoi, L. C., Broussard, J. A., Fitz, G. N., Lloyd, S. M., Kweon, J., Huffine, A. L., Burks, H. E., Hegazy, M., Amagai, S., Harms, P. W., Johnson, J. L., Urciuoli, G., Doglio, L. T., Swindell, W. R., Awatramani, R., Sprecher, E., Bao, X., Cohen-Barak, E., Missero, C., Gudjonsson, J. E., Green, K. J.

10.1101/2020.12.01.406587 — Posted: 2020-12-02

Polygenic Risk Modelling for Prediction of Epithelial Ovarian Cancer Risk

Dareng, E. O., Tyrer, J., Barnes, D. R., Jones, M. R., Yang, X., Aben, K. K. H., Adank, M. A., Agata, S. A., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Aravantinos, G., Arun, B. K., Augustinsson, A., Balmana, J., Bandera, E. V., Barkardottir, R. B., Barrowdale, D., Beckmann, M. W., Beeghly-Fadiel, A., Benitez, J., Bermisheva, M., Bernardini, M. Q., Bjorge, L., Black, A., Bogdanova, N. V., Bonanni, B., Borg, A., Brenton, J., Budzilowska, A., Butzow, R., Buys, S. S., Cai, H., Caligo, M. A., Campbell, I., Cannioto, R., Cassingham, H., Chang-Claude, J., Chanock, S. J., Chen, K., Chiew

10.1101/2020.11.30.20219220 — Posted: 2020-12-02

The Erythropoietin Receptor Stimulates Rapid Cycling and Formation of Larger Red Cells During Mouse and Human Erythropoiesis

Hidalgo, D., Bejder, J., Pop, R., Gellatly, K., Scalf, S. M., Eastman, A. E., Chen, J.-J., Zhu, L. J., Heuberger, J. A. A. C., Guo, S., Koury, M. J., Nordsborg, N. B., Socolovsky, M.

10.1101/2020.11.30.404780 — Posted: 2020-12-01

Use of dialysis, tracheostomy, and extracorporeal membrane oxygenation among 240,392 patients hospitalized with COVID-19 in the United States

Burn, E., Sena, A. G., Prats-Uribe, A., Spotnitz, M., DuVall, S., Lynch, K. E., Matheny, M. E., Nyberg, F., Ahmed, W.-U.-R., Alser, O., Alghoul, H., Alshammari, T., Zhang, L., Casajust, P., Areia, C., Shah, K., Reich, C., Blacketer, C., Andryc, A., Fortin, S., Natarajan, K., Gong, M., Golozar, A., Morales, D., Rijnbeek, P., Subbian, V., Roel, E., Recalde, M., Lane, J. C. E., Vizcaya, D., Posada, J. D., Shah, N. H., Jonnagaddala, J., Lai, L. Y. H., Aviles-Jurado, F. X., Hripcsak, G., Suchard, M. A., Ranzani, O. T., Ryan, P., Prieto-Alhambra, D., Kostka, K., Duarte-Salles, T.

10.1101/2020.11.25.20229088 — Posted: 2020-11-27

Characteristics, outcomes, and mortality amongst 133,589 patients with prevalent autoimmune diseases diagnosed with, and 48,418 hospitalised for COVID-19: a multinational distributed network cohort analysis

Tan, E. H., Sena, A. G., Prats-Uribe, A., You, S. C., Ahmed, W.-U.-R., Kostka, K., Reich, C., Duvall, S. L., Lynch, K. E., Matheny, M. E., Duarte-Salles, T., Bertolin, S. F., Hripcsak, G., Natarajan, K., Falconer, T., Spotnitz, M., Ostropolets, A., Blacketer, C., Alshammari, T. M., Alghoul, H., Alser, O., Lane, J. C. E., Dawoud, D. M., Shah, K., Yang, Y., Zhang, L., Areia, C., Golozar, A., Recalde, M., Casajust, P., Jonnagaddala, J., Subbian, V., Vizcaya, D., Lai, L. Y., Nyberg, F., Morales, D. R., Posada, J. D., Shah, N. H., Gong, M., Vivekanantham, A., Abend, A., Minty, E. P., Suchard, M. A.

10.1101/2020.11.24.20236802 — Posted: 2020-11-27

Cyto-nuclear linkage disequilibrium resulting from admixture

Fields, P., McCauley, D. E., Taylor, D.

10.1101/2020.11.24.396903 — Posted: 2020-11-26

The C99 domain of the amyloid precursor protein is a disordered membrane phase-preferring protein

Capone, R. F., Tiwari, A., Hadziselimovic, A., Peskova, Y., Hutchinson, J. M., Sanders, C. R., Kenworthy, A. K.

10.1101/2020.11.25.397893 — Posted: 2020-11-25

Actionable druggable genome-wide Mendelian randomization identifies repurposingopportunities for COVID-19

Gaziano, L., Giambartolomei, C., Pereira, A. C., Gaulton, A., Posner, D. C., Swanson, S. A., Ho, Y. L., Iyengar, S. K., Kosik, N. M., Vujkovic, M., Gagnon, D. R., Bento, A. P., Beltrao, P., Barrio Hernandez, I., Ronnblom, L., Hagberg, N., Lundtoft, C., Langenberg, C., Pietzner, M., Valentine, D., Allara, E., Surendran, P., Burgess, S., Zhao, J. H., Peters, J. E., Prins, B. P., Danesh, J., Devineni, P., Shi, Y., Lynch, K. E., DuVall, S. L., Garcon, H., Thomann, L., Zhou, J. J., Gorman, B. R., Huffman, J. E., O'Donnell, C. J., Tsao, P. S., Beckham, J. C., Pyarajan, S., Muralidhar, S., Huang, G.

10.1101/2020.11.19.20234120 — Posted: 2020-11-23

Largest GWAS (N=1,126,563) of Alzheimer's Disease Implicates Microglia and Immune Cells

Wightman, D. P., Jansen, I. E., Savage, J. E., Shadrin, A. A., Bahrami, S., Rongve, A., Borte, S., Winsvold, B. S., Drange, O. K., Martinsen, A. E., Skogholt, A. H., Willer, C., Brathen, G., Bosnes, I., Nielsen, J. B., Fritsche, L., Thomas, L. F., Pedersen, L. M., Gabrielsen, M. E., Johnsen, M. B., Meisingset, T. W., Zhou, W., Proitsi, P., Hodges, A., Dobson, R., Velayudhan, L., 23andMe Research Team, , Sealock, J. M., Davis, L. K., Pedersen, N. L., Reynolds, C. A., Karlsson, I. K., Magnusson, S., Stefansson, H., Thordardottir, S., Jonsson, P. V., Snaedal, J., Zettergren, A., Skoog, I., Kern

10.1101/2020.11.20.20235275 — Posted: 2020-11-23

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