Channel: Vanderbilt University

This collection includes bioRxiv and medRxiv papers from authors at Vanderbilt University.

2602 Articles

The C99 domain of the amyloid precursor protein is a disordered membrane phase-preferring protein

Capone, R. F., Tiwari, A., Hadziselimovic, A., Peskova, Y., Hutchinson, J. M., Sanders, C. R., Kenworthy, A. K.

10.1101/2020.11.25.397893 — Posted: 2020-11-25

Actionable druggable genome-wide Mendelian randomization identifies repurposingopportunities for COVID-19

Gaziano, L., Giambartolomei, C., Pereira, A. C., Gaulton, A., Posner, D. C., Swanson, S. A., Ho, Y. L., Iyengar, S. K., Kosik, N. M., Vujkovic, M., Gagnon, D. R., Bento, A. P., Beltrao, P., Barrio Hernandez, I., Ronnblom, L., Hagberg, N., Lundtoft, C., Langenberg, C., Pietzner, M., Valentine, D., Allara, E., Surendran, P., Burgess, S., Zhao, J. H., Peters, J. E., Prins, B. P., Danesh, J., Devineni, P., Shi, Y., Lynch, K. E., DuVall, S. L., Garcon, H., Thomann, L., Zhou, J. J., Gorman, B. R., Huffman, J. E., O'Donnell, C. J., Tsao, P. S., Beckham, J. C., Pyarajan, S., Muralidhar, S., Huang, G.

10.1101/2020.11.19.20234120 — Posted: 2020-11-23

Largest GWAS (N=1,126,563) of Alzheimer's Disease Implicates Microglia and Immune Cells

Wightman, D. P., Jansen, I. E., Savage, J. E., Shadrin, A. A., Bahrami, S., Rongve, A., Borte, S., Winsvold, B. S., Drange, O. K., Martinsen, A. E., Skogholt, A. H., Willer, C., Brathen, G., Bosnes, I., Nielsen, J. B., Fritsche, L., Thomas, L. F., Pedersen, L. M., Gabrielsen, M. E., Johnsen, M. B., Meisingset, T. W., Zhou, W., Proitsi, P., Hodges, A., Dobson, R., Velayudhan, L., 23andMe Research Team, , Sealock, J. M., Davis, L. K., Pedersen, N. L., Reynolds, C. A., Karlsson, I. K., Magnusson, S., Stefansson, H., Thordardottir, S., Jonsson, P. V., Snaedal, J., Zettergren, A., Skoog, I., Kern

10.1101/2020.11.20.20235275 — Posted: 2020-11-23

IBEX: A versatile multi-plex optical imaging approach for deep phenotyping and spatial analysis of cells in complex tissues

Radtke, A. J., Kandov, E., Lowekamp, B., Speranza, E., Chu, C. J., Gola, A., Thakur, N., Shih, R., Yao, L., Yaniv, Z. R., Beuschel, R. T., Kabat, J., Croteau, J., Davis, J., Hernandez, J. M., Germain, R. N.

10.1101/2020.11.20.390690 — Posted: 2020-11-21

Rooting the animal tree of life

Li, Y., Shen, X.-X., Evans, B., Dunn, C. W., Rokas, A.

10.1101/2020.10.27.357798 — Posted: 2020-11-20

Disentangling genetic feature selection and aggregation in transcriptome-wide association studies

Cao, C., Kwok, D., Li, Q., He, J., Guo, X., Zhang, Q., Long, Q.

10.1101/2020.11.19.390617 — Posted: 2020-11-20

Polygenic transcriptome risk scores improve portability of polygenic risk scores across ancestries

Liang, Y., Pividori, M., Manichaikul, A., Palmer, A. A., Cox, N. J., Wheeler, H. E., Im, H. K.

10.1101/2020.11.12.373647 — Posted: 2020-11-18

Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the unfolded protein response (UPR) in models of neurodegeneration

Vidal, R. L., Sepulveda, D., Troncoso-Escudero, P., Garcia-Huerta, P., Gonzalez, C., Plate, L., Jerez, C., Canovas, J., Rivera, C., Castillo, V., Cisternas, M., Leal, S., Martinez, A., Grandjean, J., Lashuel, H., Martin, A. J. M., Latapiat, V., Matus, S., Sardi, S. P., Wiseman, L., Hetz, C.

10.1101/2020.11.17.387480 — Posted: 2020-11-18

Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer

Zekavat, S. M., Lin, S.-H., Bick, A. G., Liu, A., Paruchuri, K., Uddin, M. M., Ye, Y., Yu, Z., Liu, X., Kamatani, Y., Pirruccello, J. P., Pampana, A., Loh, P.-R., Kohli, P., McCarroll, S. A., Neale, B., Engels, E. E., Brown, D. W., Smoller, J. W., Green, R., Karlson, E. W., Lebo, M., Ellinor, P., Weiss, S. T., Daly, M. J., The BioBank Japan Project, , FinnGen Consortium, , Terao, C., Zhao, H., Ebert, B. L., COVID-19 Host Genetics Initiative, , Ganna, A., Machiela, M. J., Genovese, G., Natarajan, P.

10.1101/2020.11.12.20230821 — Posted: 2020-11-16

Empirical field mapping for gradient nonlinearity correction of multi-site diffusion weighted MRI

Hansen, C. B., Rogers, B. P., Schilling, K. G., Nath, V., Blaber, J. A., Irfanoglu, O., Barnett, A., Pierpaoli, C., Anderson, A. W., Landman, B. A.

10.1101/2020.05.18.102558 — Posted: 2020-11-16

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