Channel: Vanderbilt University

This collection includes bioRxiv and medRxiv papers from authors at Vanderbilt University.

3236 Articles

Metformin reduces SARS-CoV-2 in a Phase 3 Randomized Placebo Controlled Clinical Trial

Bramante, C. T., Beckman, K. B., Mehta, T., Krager, A. B., Odde, D. J., Tignanelli, C. J., Buse, J. B., Johnson, D. M., Watson, R. H. B., Daniel, J. J., Liebovitz, D. M., Nicklas, J. M., Cohen, K., Puskarich, M. A., Belani, H. K., Siegel, L. K., Klatt, N. R., Anderson, B., Hartman, K. M., Rao, V., Hagan, A. A., Patel, B., Fenno, S. L., Avula, N., Reddy, N. V., Erickson, S. M., Fricton, R. D., Lee, S., Griffiths, G., Pullen, M. F., Thompson, J. L., Sherwood, N., Murray, T. A., Rose, M. R., Boulware, D. R., Huling, J. D.

10.1101/2023.06.06.23290989 — Posted: 2023-06-07

Association of alpha-aminoadipic acid (2-AAA) with cardiometabolic risk factors in healthy and high-risk individuals

Desine, S., Gabriel, C. L., Smith, H. M., Antonetti, O. R., Wang, C., Calcutt, M. W., Doran, A. C., Silver, H. J., Nair, S., Terry, J. G., Carr, J. J., Linton, M. F., Brown, J. D., Koethe, J. R., Ferguson, J. F.

10.1101/2023.06.05.23290990 — Posted: 2023-06-06

Removing the Gβγ-SNAP25 brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity

Ceddia, R. P., Zurawski, Z., Thompson Gray, A., Adegboye, F., McDonald-Boyer, A., Shi, F., Liu, D., Maldonado, J., Feng, J., Li, Y., Alford, S., Ayala, J. E., McGuinness, O. P., Collins, S., Hamm, H. E.

10.1101/2020.04.29.069138 — Posted: 2023-06-06

Measuring Social Determinants of Health in the All of Us Research Program: Technical Document

Tesfaye, S., Cronin, R., Lopez-Class, M., Chen, Q., Foster, C. S., Gu, C., Guide, A., Hiatt, R. A., Johnson, A., Joseph, C. L., Khatri, P., Lim, S., Litwin, T. R., Munoz, F. A., Ramirez, A., Sansbury, H., Schlundt, D. G., Viera, E. N., Dede-Yildirim, E., Clark, C. R.

10.1101/2023.06.01.23290404 — Posted: 2023-06-05

DNA methylation signatures of early life adversity are exposure-dependent in wild baboons

Anderson, J. A., Lin, D., Lea, A. J., Johnston, R. A., Voyles, T., Akinyi, M. Y., Archie, E., Alberts, S. C., Tung, J.

10.1101/2023.06.05.542485 — Posted: 2023-06-05

Identifying modifiable comorbidities of schizophrenia by integrating electronic health records and polygenic risk

Vessels, T. J., Strayer, N. J., Choi, K. W., Lee, H., Zhang, S., Han, L., Morley, T. J., Smoller, J. W., Xu, Y., Ruderfer, D. M.

10.1101/2023.06.01.23290057 — Posted: 2023-06-05

Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease

Yang, H.-S., Teng, L., Kang, D., Menon, V., Ge, T., Finucane, H. K., Schultz, A. P., Properzi, M. J., Klein, H.-U., Chibnik, L. B., Schneider, J. A., Bennett, D. A., Hohman, T. J., Mayeux, R. P., Johnson, K. A., De Jager, P. L., Sperling, R. A.

10.1101/2023.06.01.23290850 — Posted: 2023-06-05

Selection, optimization, and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse populations

Lennon, N. J., Kottyan, L. C., Kachulis, C., Abul-Husn, N., Arias, J., Belbin, G., Below, J. E., Berndt, S., Chung, W., Cimino, J. J., Clayton, E. W., Connolly, J. J., Crosslin, D., Dikilitas, O., Edwards, D. R. V., Feng, Q., Fisher, M., Freimuth, R., Ge, T., Glessner, J. T., Gordon, A., Guiducci, C., Hakonarson, H., Harden, M., Harr, M., Hirschhorn, J., Hoggart, C., Hsu, L., Irvin, R., Jarvik, G. P., Karlson, E. W., Karlson, E. W., Khan, A., Khera, A., Kiryluk, K., Kullo, I., Larkin, K., Limdi, N., Linder, J. E., Loos, R., Luo, Y., Malolepsza, E., Manolio, T., Martin, L. J., McCarthy, L., Mei

10.1101/2023.05.25.23290535 — Posted: 2023-06-05

Eosinophils exert direct and indirect anti-tumorigenic effects in the development of esophageal squamous cell carcinoma

Jacobse, J., Aziz, Z., Sun, L., Chaparro, J., Pilat, J. M., Kwag, A., Buendia, M., Wimbiscus, M., Nasu, M., Saito, T., Mine, S., Orita, H., Revetta, F., Short, S., Washington, M. K., Hiremath, G., Gibson, M., Coburn, L. A., Koyama, T., Goettel, J., Williams, C., Choksi, Y. A.

10.1101/2023.06.01.543287 — Posted: 2023-06-05

Comparison of the Multivariate Genetic Architecture of Eight Major Psychiatric Disorders Across Sex

Schwaba, T., Mallard, T. T., Maihofer, A. X., Rhemtulla, M., Lee, P. H., Smoller, J. W., Davis, L. K., Nivard, M. G., Grotzinger, A. D., Tucker-Drob, E. M.

10.1101/2023.05.25.23290545 — Posted: 2023-06-05

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