Channel: Fred Hutchinson Cancer Center

This collection includes bioRxiv and medRxiv papers from authors at Fred Hutchinson Cancer Center.

1054 Articles

Cytomegaloviral determinants of CD8+ T cell programming and RhCMV/SIV vaccine efficacy

Malouli, D., Hansen, S. G., Hancock, M. H., Hughes, C. M., Ford, J. C., Gilbride, R. M., Ventura, A. B., Morrow, D., Taher, H., Uebelhoer, L. S., McArdle, M. R., Papen, C. R., Espinosa Trethewy, R., Oswald, K., Shoemaker, R., Berkemeier, B., Bosche, W., Hull, M., Green, J., Axthelm, M. K., Shao, J., Edlefsen, P., Grey, F., Nelson, J. A., Lifson, J. D., Streblow, D. N., Sacha, J., Früh, K., Picker, L. J.

10.1101/2020.09.30.321349 — Posted: 2020-10-01

Viral genomes reveal patterns of the SARS-CoV-2 outbreak in Washington State

Mueller, N. F., Wagner, C., Frazar, C. D., Roychoudhury, P., Lee, J., Moncla, L. H., Pelle, B., Richardson, M., Ryke, E., Xie, H., Shrestha, L., Addetia, A., Rachleff, V. M., Lieberman, N., Huang, M.-L., Gautom, R., Melly, G., Hiatt, B., Dykema, P., Adler, A., Brandstetter, E., Han, P. D., Fay, K., Ilcisin, M., Lacombe, K., Sibley, T. R., Truong, M., Wolf, C. R., Boeckh, M., Englund, J. A., Famulare, M., Lutz, B. R., Rieder, M. J., Thompson, M., Duchin, J. S., Starita, L. M., Chu, H. Y., Shendure, J., Jerome, K. R., Lindquist, S., Greninger, A., Nickerson, D. A., Bedford, T.

10.1101/2020.09.30.20204230 — Posted: 2020-09-30

An optimal set of inhibitors for Reverse Engineering via Kinase Regularization.

Rata, S., Gruver, J. S., Trikoz, N., Lukyanov, A., Vultaggio, J., Ceribelli, M., Thomas, C., Gujral, T. S., Kirschner, M. W., Peshkin, L.

10.1101/2020.09.26.312348 — Posted: 2020-09-28

A rapidly evolving actin mediates fertility and developmental tradeoffs in Drosophila

Schroeder, C. M., Tomlin, S. A., Valenzuela, J. R., Malik, H. S.

10.1101/2020.09.28.317503 — Posted: 2020-09-28

Wrong person, place and time: viral load and contact network structure predict SARS-CoV-2 transmission and super-spreading events

Goyal, A., Reeves, D. B., Cardozo-Ojeda, E. F., Schiffer, J. T., Mayer, B. T.

10.1101/2020.08.07.20169920 — Posted: 2020-09-28

Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition

Greaney, A. J., Starr, T. N., Gilchuk, P., Zost, S. J., Binshtein, E., Loes, A. N., Hilton, S. K., Huddleston, J., Eguia, R., Crawford, K. H., Dingens, A. S., Nargi, R. S., Sutton, R. E., Suryadevara, N., Rothlauf, P. W., Liu, Z., Whelan, S. P., Carnahan, R. H., Crowe, J. E., Bloom, J. D.

10.1101/2020.09.10.292078 — Posted: 2020-09-28

Outcomes associated with SARS-CoV-2 viral clades in COVID-19

Nakamichi, K., Shen, J. Z., Lee, C. S., Lee, A. Y., Roberts, E. A., Simonson, P. D., Roychoudhury, P., Andriesen, J. G., Randhawa, A. K., Mathias, P. C., Greninger, A., Jerome, K. R., Van Gelder, R. N.

10.1101/2020.09.24.20201228 — Posted: 2020-09-25

Development of antibody-dependent cell cytotoxicity function in HIV-1 antibodies

Doepker, L. E., Danon, S., Harkins, E., Ralph, D., Yaffe, Z., Dhar, A., Wagner, C., Stumpf, M., Arenz, D., Williams, J. A., Jaoko, W., Mandaliya, K., Lee, K. K., Matsen, F. A., Overbaugh, J.

10.1101/2020.09.24.312066 — Posted: 2020-09-25

Safety and immunogenicity of the Ad26.COV2.S COVID-19 vaccine candidate: interim results of a phase 1/2a, double-blind, randomized, placebo-controlled trial

Sadoff, J., Le Gars, M., Shukarev, G., Heerwegh, D., Truyers, C., de Groot, A. M., Stoop, J., Tete, S., Van Damme, W., Leroux-Roels, I., Berghmans, P.-J., Kimmel, M., Van Damme, P., De Hoon, J., Smith, W., Stephenson, K., Barouch, D., De Rosa, S., Cohen, K., McElrath, J., Cormier, E., Scheper, G., Hendriks, J., Struyf, F., Douoguih, M., Van Hoof, J., Schuitemaker, H.

10.1101/2020.09.23.20199604 — Posted: 2020-09-25

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Mahajan, A., Spracklen, C. N., Zhang, W., Ng, M. C., Petty, L. E., Kitajima, H., Yu, G. Z., Rueger, S., Speidel, L., Kim, Y. J., Horikoshi, M., Mercader, J. M., Taliun, D., Moon, S., Kwak, S.-H., Robertson, N. R., Rayner, N. W., Loh, M., Kim, B.-J., Chiou, J., Miguel-Escalada, I., della Briotta Parolo, P., Lin, K., Bragg, F., Preuss, M. H., Takeuchi, F., Nano, J., Guo, X., Lamri, A., Nakatochi, M., Scott, R. A., Lee, J.-J., Huerta-Chagoya, A., Graff, M., Chai, J.-F., Parra, E. J., Yao, J., Bielak, L. F., Tabara, Y., Hai, Y., Steinthorsdottir, V., Cook, J. P., Kals, M., Grarup, N., Schmidt, E.

10.1101/2020.09.22.20198937 — Posted: 2020-09-23

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